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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MSX2
Full Name:
Homeobox protein MSX-2
Alias:
CRS2; FPP; Homeobox MSX-2; HOX8; Hox-8; MSH; Msh homeo box 2; Msh homeobox 2; PFM; PFM1
Type:
Transcription, coactivator/corepressor
Mass (Da):
28870
Number AA:
267
UniProt ID:
P35548
International Prot ID:
IPI00292686
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0001501
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
S
K
G
N
D
L
F
S
P
D
E
E
G
P
A
Site 2
S43
E
E
R
R
V
K
V
S
S
L
P
F
S
V
E
Site 3
S44
E
R
R
V
K
V
S
S
L
P
F
S
V
E
A
Site 4
S54
F
S
V
E
A
L
M
S
D
K
K
P
P
K
E
Site 5
S63
K
K
P
P
K
E
A
S
P
L
P
A
E
S
A
Site 6
S82
T
L
R
P
L
L
L
S
G
H
G
A
R
E
A
Site 7
S91
H
G
A
R
E
A
H
S
P
G
P
L
V
K
P
Site 8
T101
P
L
V
K
P
F
E
T
A
S
V
K
S
E
N
Site 9
S103
V
K
P
F
E
T
A
S
V
K
S
E
N
S
E
Site 10
Y122
W
M
Q
E
P
G
R
Y
S
P
P
P
R
H
T
Site 11
S123
M
Q
E
P
G
R
Y
S
P
P
P
R
H
T
S
Site 12
T129
Y
S
P
P
P
R
H
T
S
P
T
T
C
T
L
Site 13
S130
S
P
P
P
R
H
T
S
P
T
T
C
T
L
R
Site 14
T132
P
P
R
H
T
S
P
T
T
C
T
L
R
K
H
Site 15
T133
P
R
H
T
S
P
T
T
C
T
L
R
K
H
K
Site 16
T135
H
T
S
P
T
T
C
T
L
R
K
H
K
T
N
Site 17
T141
C
T
L
R
K
H
K
T
N
R
K
P
R
T
P
Site 18
T147
K
T
N
R
K
P
R
T
P
F
T
T
S
Q
L
Site 19
T150
R
K
P
R
T
P
F
T
T
S
Q
L
L
A
L
Site 20
S152
P
R
T
P
F
T
T
S
Q
L
L
A
L
E
R
Site 21
Y166
R
K
F
R
Q
K
Q
Y
L
S
I
A
E
R
A
Site 22
S168
F
R
Q
K
Q
Y
L
S
I
A
E
R
A
E
F
Site 23
S177
A
E
R
A
E
F
S
S
S
L
N
L
T
E
T
Site 24
S178
E
R
A
E
F
S
S
S
L
N
L
T
E
T
Q
Site 25
T182
F
S
S
S
L
N
L
T
E
T
Q
V
K
I
W
Site 26
T184
S
S
L
N
L
T
E
T
Q
V
K
I
W
F
Q
Site 27
S234
S
S
P
L
Q
A
A
S
I
Y
G
A
S
Y
P
Site 28
Y236
P
L
Q
A
A
S
I
Y
G
A
S
Y
P
F
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation