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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COPB2
Full Name:
Coatomer subunit beta'
Alias:
Beta'-coat protein; Beta'-COP; Betaprime-COP; Coatomer beta' subunit; Coatomer binding complex, beta prime subunit; Coatomer protein complex, subunit beta 2 (beta prime); P102
Type:
Vesicle protein
Mass (Da):
102487
Number AA:
906
UniProt ID:
P35606
International Prot ID:
IPI00220219
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030126
GO:0005829
GO:0005794
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005198
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0048205
GO:0006891
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
L
D
I
K
R
K
L
T
A
R
S
D
R
V
K
Site 2
S15
K
R
K
L
T
A
R
S
D
R
V
K
S
V
D
Site 3
S20
A
R
S
D
R
V
K
S
V
D
L
H
P
T
E
Site 4
T26
K
S
V
D
L
H
P
T
E
P
W
M
L
A
S
Site 5
T52
E
T
Q
T
L
V
K
T
F
E
V
C
D
L
P
Site 6
Y86
M
Q
I
R
V
F
N
Y
N
T
L
E
R
V
H
Site 7
Y101
M
F
E
A
H
S
D
Y
I
R
C
I
A
V
H
Site 8
S162
N
N
Q
F
A
S
A
S
L
D
R
T
I
K
V
Site 9
T166
A
S
A
S
L
D
R
T
I
K
V
W
Q
L
G
Site 10
S174
I
K
V
W
Q
L
G
S
S
S
P
N
F
T
L
Site 11
S175
K
V
W
Q
L
G
S
S
S
P
N
F
T
L
E
Site 12
S176
V
W
Q
L
G
S
S
S
P
N
F
T
L
E
G
Site 13
T180
G
S
S
S
P
N
F
T
L
E
G
H
E
K
G
Site 14
Y193
K
G
V
N
C
I
D
Y
Y
S
G
G
D
K
P
Site 15
Y194
G
V
N
C
I
D
Y
Y
S
G
G
D
K
P
Y
Site 16
Y201
Y
S
G
G
D
K
P
Y
L
I
S
G
A
D
D
Site 17
Y216
R
L
V
K
I
W
D
Y
Q
N
K
T
C
V
Q
Site 18
S233
E
G
H
A
Q
N
V
S
C
A
S
F
H
P
E
Site 19
T252
I
T
G
S
E
D
G
T
V
R
I
W
H
S
S
Site 20
S259
T
V
R
I
W
H
S
S
T
Y
R
L
E
S
T
Site 21
T260
V
R
I
W
H
S
S
T
Y
R
L
E
S
T
L
Site 22
S265
S
S
T
Y
R
L
E
S
T
L
N
Y
G
M
E
Site 23
T266
S
T
Y
R
L
E
S
T
L
N
Y
G
M
E
R
Site 24
Y269
R
L
E
S
T
L
N
Y
G
M
E
R
V
W
C
Site 25
S279
E
R
V
W
C
V
A
S
L
R
G
S
N
N
V
Site 26
S307
G
R
E
E
P
A
M
S
M
D
A
N
G
K
I
Site 27
S350
L
A
V
K
D
M
G
S
C
E
I
Y
P
Q
T
Site 28
Y354
D
M
G
S
C
E
I
Y
P
Q
T
I
Q
H
N
Site 29
Y378
G
D
G
E
Y
I
I
Y
T
A
M
A
L
R
N
Site 30
S387
A
M
A
L
R
N
K
S
F
G
S
A
Q
E
F
Site 31
S400
E
F
A
W
A
H
D
S
S
E
Y
A
I
R
E
Site 32
S401
F
A
W
A
H
D
S
S
E
Y
A
I
R
E
S
Site 33
S408
S
E
Y
A
I
R
E
S
N
S
I
V
K
I
F
Site 34
S423
K
N
F
K
E
K
K
S
F
K
P
D
F
G
A
Site 35
Y450
S
V
N
G
L
A
F
Y
D
W
D
N
T
E
L
Site 36
Y545
S
S
V
N
R
L
N
Y
Y
V
G
G
E
I
V
Site 37
Y546
S
V
N
R
L
N
Y
Y
V
G
G
E
I
V
T
Site 38
T560
T
I
A
H
L
D
R
T
M
Y
L
L
G
Y
I
Site 39
Y562
A
H
L
D
R
T
M
Y
L
L
G
Y
I
P
K
Site 40
Y566
R
T
M
Y
L
L
G
Y
I
P
K
D
N
R
L
Site 41
Y574
I
P
K
D
N
R
L
Y
L
G
D
K
E
L
N
Site 42
S604
A
V
M
R
R
D
F
S
M
A
D
K
V
L
P
Site 43
T612
M
A
D
K
V
L
P
T
I
P
K
E
Q
R
T
Site 44
T636
G
F
K
Q
Q
A
L
T
V
S
T
D
P
E
H
Site 45
S679
Q
L
A
E
L
A
I
S
K
C
Q
F
G
L
A
Site 46
Y732
N
N
V
A
F
M
S
Y
F
L
Q
G
K
V
D
Site 47
S764
L
A
R
T
Y
L
P
S
Q
V
S
R
V
V
K
Site 48
S767
T
Y
L
P
S
Q
V
S
R
V
V
K
L
W
R
Site 49
S787
V
N
Q
K
A
A
E
S
L
A
D
P
T
E
Y
Site 50
T792
A
E
S
L
A
D
P
T
E
Y
E
N
L
F
P
Site 51
Y794
S
L
A
D
P
T
E
Y
E
N
L
F
P
G
L
Site 52
Y824
D
L
W
P
A
K
Q
Y
P
L
V
T
P
N
E
Site 53
T828
A
K
Q
Y
P
L
V
T
P
N
E
E
R
N
V
Site 54
T848
D
F
Q
P
S
R
S
T
A
Q
Q
E
L
D
G
Site 55
S859
E
L
D
G
K
P
A
S
P
T
P
V
I
V
A
Site 56
T861
D
G
K
P
A
S
P
T
P
V
I
V
A
S
H
Site 57
S867
P
T
P
V
I
V
A
S
H
T
A
N
K
E
E
Site 58
T869
P
V
I
V
A
S
H
T
A
N
K
E
E
K
S
Site 59
S876
T
A
N
K
E
E
K
S
L
L
E
L
E
V
D
Site 60
T894
L
E
L
E
D
I
D
T
T
D
I
N
L
D
E
Site 61
T895
E
L
E
D
I
D
T
T
D
I
N
L
D
E
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation