PhosphoNET

           
Protein Info 
   
Short Name:  FUS
Full Name:  RNA-binding protein FUS
Alias:  16) in malignant liposarcoma); 75 kDa DNA-pairing protein; ALS6; FUS1; Fusion (involved in t (12; Fusion, derived from t(12;16) malignant liposarcoma; Heterogeneous nuclear ribonucleoprotein P2; Oncogene FUS; Oncogene TLS; POMp75; TLS; Translocated in liposarcoma; Translocated in liposarcoma protein
Type:  DNA binding protein; Nuclear receptor co-regulator; RNA binding protein
Mass (Da):  53426
Number AA:  526
UniProt ID:  P35637
International Prot ID:  IPI00260715
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0003723  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0008219  GO:0000398   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y17ATQSYGAYPTQPGQG
Site 2T19QSYGAYPTQPGQGYS
Site 3Y25PTQPGQGYSQQSSQP
Site 4S26TQPGQGYSQQSSQPY
Site 5S29GQGYSQQSSQPYGQQ
Site 6S30QGYSQQSSQPYGQQS
Site 7Y33SQQSSQPYGQQSYSG
Site 8S37SQPYGQQSYSGYSQS
Site 9S39PYGQQSYSGYSQSTD
Site 10S42QQSYSGYSQSTDTSG
Site 11S44SYSGYSQSTDTSGYG
Site 12S48YSQSTDTSGYGQSSY
Site 13Y50QSTDTSGYGQSSYSS
Site 14S53DTSGYGQSSYSSYGQ
Site 15S54TSGYGQSSYSSYGQS
Site 16Y55SGYGQSSYSSYGQSQ
Site 17S56GYGQSSYSSYGQSQN
Site 18S57YGQSSYSSYGQSQNT
Site 19Y58GQSSYSSYGQSQNTG
Site 20S61SYSSYGQSQNTGYGT
Site 21Y66GQSQNTGYGTQSTPQ
Site 22S70NTGYGTQSTPQGYGS
Site 23T71TGYGTQSTPQGYGST
Site 24Y75TQSTPQGYGSTGGYG
Site 25S77STPQGYGSTGGYGSS
Site 26Y81GYGSTGGYGSSQSSQ
Site 27S83GSTGGYGSSQSSQSS
Site 28S84STGGYGSSQSSQSSY
Site 29S86GGYGSSQSSQSSYGQ
Site 30S87GYGSSQSSQSSYGQQ
Site 31S89GSSQSSQSSYGQQSS
Site 32S90SSQSSQSSYGQQSSY
Site 33Y91SQSSQSSYGQQSSYP
Site 34S95QSSYGQQSSYPGYGQ
Site 35S96SSYGQQSSYPGYGQQ
Site 36Y97SYGQQSSYPGYGQQP
Site 37Y100QQSSYPGYGQQPAPS
Site 38S107YGQQPAPSSTSGSYG
Site 39S108GQQPAPSSTSGSYGS
Site 40S110QPAPSSTSGSYGSSS
Site 41S112APSSTSGSYGSSSQS
Site 42Y113PSSTSGSYGSSSQSS
Site 43S115STSGSYGSSSQSSSY
Site 44S116TSGSYGSSSQSSSYG
Site 45S117SGSYGSSSQSSSYGQ
Site 46S119SYGSSSQSSSYGQPQ
Site 47S120YGSSSQSSSYGQPQS
Site 48S121GSSSQSSSYGQPQSG
Site 49Y122SSSQSSSYGQPQSGS
Site 50S127SSYGQPQSGSYSQQP
Site 51S129YGQPQSGSYSQQPSY
Site 52S131QPQSGSYSQQPSYGG
Site 53S135GSYSQQPSYGGQQQS
Site 54Y136SYSQQPSYGGQQQSY
Site 55S142SYGGQQQSYGQQQSY
Site 56Y143YGGQQQSYGQQQSYN
Site 57S148QSYGQQQSYNPPQGY
Site 58Y149SYGQQQSYNPPQGYG
Site 59Y161GYGQQNQYNSSSGGG
Site 60S163GQQNQYNSSSGGGGG
Site 61S164QQNQYNSSSGGGGGG
Site 62S165QNQYNSSSGGGGGGG
Site 63Y177GGGGGGNYGQDQSSM
Site 64S182GNYGQDQSSMSSGGG
Site 65S183NYGQDQSSMSSGGGS
Site 66S185GQDQSSMSSGGGSGG
Site 67S186QDQSSMSSGGGSGGG
Site 68S190SMSSGGGSGGGYGNQ
Site 69Y194GGGSGGGYGNQDQSG
Site 70S200GYGNQDQSGGGGSGG
Site 71Y208GGGGSGGYGQQDRGG
Site 72S221GGRGRGGSGGGGGGG
Site 73Y232GGGGGGGYNRSSGGY
Site 74S235GGGGYNRSSGGYEPR
Site 75S236GGGYNRSSGGYEPRG
Site 76Y239YNRSSGGYEPRGRGG
Site 77S257GRGGMGGSDRGGFNK
Site 78S273GGPRDQGSRHDSEQD
Site 79S277DQGSRHDSEQDNSDN
Site 80S282HDSEQDNSDNNTIFV
Site 81T286QDNSDNNTIFVQGLG
Site 82Y304TIESVADYFKQIGII
Site 83T313KQIGIIKTNKKTGQP
Site 84T317IIKTNKKTGQPMINL
Site 85Y325GQPMINLYTDRETGK
Site 86T326QPMINLYTDRETGKL
Site 87T330NLYTDRETGKLKGEA
Site 88T338GKLKGEATVSFDDPP
Site 89S340LKGEATVSFDDPPSA
Site 90S346VSFDDPPSAKAAIDW
Site 91S360WFDGKEFSGNPIKVS
Site 92S367SGNPIKVSFATRRAD
Site 93Y397GPMGRGGYGGGGSGG
Site 94S402GGYGGGGSGGGGRGG
Site 95S412GGRGGFPSGGGGGGG
Site 96S462PGGGPGGSHMGGNYG
Site 97Y468GSHMGGNYGDDRRGG
Site 98Y479RRGGRGGYDRGGYRG
Site 99Y484GGYDRGGYRGRGGDR
Site 100S513FGPGKMDSRGEHRQD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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