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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CHOP
Full Name:
DNA damage-inducible transcript 3 protein
Alias:
C/EBP-homologous protein;C/EBP-homologous protein 10;Growth arrest and DNA damage-inducible protein GADD153
Type:
Transcription protein
Mass (Da):
19175
Number AA:
169
UniProt ID:
P35638
International Prot ID:
IPI00019956
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0046983
GO:0043565
GO:0003714
PhosphoSite+
KinaseNET
Biological Process:
GO:0007050
GO:0045454
GO:0042789
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
S
L
P
F
S
F
G
T
L
S
S
W
E
L
E
Site 2
S14
P
F
S
F
G
T
L
S
S
W
E
L
E
A
W
Site 3
S15
F
S
F
G
T
L
S
S
W
E
L
E
A
W
Y
Site 4
Y22
S
W
E
L
E
A
W
Y
E
D
L
Q
E
V
L
Site 5
S30
E
D
L
Q
E
V
L
S
S
D
E
N
G
G
T
Site 6
S31
D
L
Q
E
V
L
S
S
D
E
N
G
G
T
Y
Site 7
T37
S
S
D
E
N
G
G
T
Y
V
S
P
P
G
N
Site 8
Y38
S
D
E
N
G
G
T
Y
V
S
P
P
G
N
E
Site 9
S40
E
N
G
G
T
Y
V
S
P
P
G
N
E
E
E
Site 10
S49
P
G
N
E
E
E
E
S
K
I
F
T
T
L
D
Site 11
T53
E
E
E
S
K
I
F
T
T
L
D
P
A
S
L
Site 12
T54
E
E
S
K
I
F
T
T
L
D
P
A
S
L
A
Site 13
T64
P
A
S
L
A
W
L
T
E
E
E
P
E
P
A
Site 14
S75
P
E
P
A
E
V
T
S
T
S
Q
S
P
H
S
Site 15
T76
E
P
A
E
V
T
S
T
S
Q
S
P
H
S
P
Site 16
S77
P
A
E
V
T
S
T
S
Q
S
P
H
S
P
D
Site 17
S79
E
V
T
S
T
S
Q
S
P
H
S
P
D
S
S
Site 18
S82
S
T
S
Q
S
P
H
S
P
D
S
S
Q
S
S
Site 19
S85
Q
S
P
H
S
P
D
S
S
Q
S
S
L
A
Q
Site 20
S86
S
P
H
S
P
D
S
S
Q
S
S
L
A
Q
E
Site 21
S89
S
P
D
S
S
Q
S
S
L
A
Q
E
E
E
E
Site 22
S108
R
T
R
K
R
K
Q
S
G
H
S
P
A
R
A
Site 23
S111
K
R
K
Q
S
G
H
S
P
A
R
A
G
K
Q
Site 24
T149
K
Q
E
I
E
R
L
T
R
E
V
E
A
T
R
Site 25
T155
L
T
R
E
V
E
A
T
R
R
A
L
I
D
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation