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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SOX5
Full Name:
Transcription factor SOX-5
Alias:
L-SOX5; MGC35153; SRY (sex determining region Y)-box 5
Type:
Transcription factor
Mass (Da):
84026
Number AA:
763
UniProt ID:
P35711
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006366
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
P
Q
E
F
E
R
M
S
S
K
R
P
A
S
P
Site 2
S16
Q
E
F
E
R
M
S
S
K
R
P
A
S
P
Y
Site 3
S21
M
S
S
K
R
P
A
S
P
Y
G
E
A
D
G
Site 4
Y23
S
K
R
P
A
S
P
Y
G
E
A
D
G
E
V
Site 5
S44
Q
K
V
E
E
E
E
S
D
G
L
P
A
F
H
Site 6
S57
F
H
L
P
L
H
V
S
F
P
N
K
P
H
S
Site 7
S64
S
F
P
N
K
P
H
S
E
E
F
Q
P
V
S
Site 8
S71
S
E
E
F
Q
P
V
S
L
L
T
Q
E
T
C
Site 9
T74
F
Q
P
V
S
L
L
T
Q
E
T
C
G
H
R
Site 10
T82
Q
E
T
C
G
H
R
T
P
T
S
Q
H
N
T
Site 11
T84
T
C
G
H
R
T
P
T
S
Q
H
N
T
M
E
Site 12
T89
T
P
T
S
Q
H
N
T
M
E
V
D
G
N
K
Site 13
S100
D
G
N
K
V
M
S
S
F
A
P
H
N
S
S
Site 14
S106
S
S
F
A
P
H
N
S
S
T
S
P
Q
K
A
Site 15
S107
S
F
A
P
H
N
S
S
T
S
P
Q
K
A
E
Site 16
S109
A
P
H
N
S
S
T
S
P
Q
K
A
E
E
G
Site 17
S120
A
E
E
G
G
R
Q
S
G
E
S
L
S
S
T
Site 18
S123
G
G
R
Q
S
G
E
S
L
S
S
T
A
L
G
Site 19
S125
R
Q
S
G
E
S
L
S
S
T
A
L
G
T
P
Site 20
S126
Q
S
G
E
S
L
S
S
T
A
L
G
T
P
E
Site 21
T127
S
G
E
S
L
S
S
T
A
L
G
T
P
E
R
Site 22
T131
L
S
S
T
A
L
G
T
P
E
R
R
K
G
S
Site 23
S138
T
P
E
R
R
K
G
S
L
A
D
V
V
D
T
Site 24
T145
S
L
A
D
V
V
D
T
L
K
Q
R
K
M
E
Site 25
T162
I
K
N
E
P
E
E
T
P
S
I
E
K
L
L
Site 26
S164
N
E
P
E
E
T
P
S
I
E
K
L
L
S
K
Site 27
S170
P
S
I
E
K
L
L
S
K
D
W
K
D
K
L
Site 28
S182
D
K
L
L
A
M
G
S
G
N
F
G
E
I
K
Site 29
T191
N
F
G
E
I
K
G
T
P
E
S
L
A
E
K
Site 30
S194
E
I
K
G
T
P
E
S
L
A
E
K
E
R
Q
Site 31
S229
E
Q
K
K
L
A
A
S
Q
I
E
K
Q
R
Q
Site 32
Y314
K
A
G
C
S
D
P
Y
P
V
Q
L
I
P
T
Site 33
S352
Q
L
A
A
M
Q
V
S
P
G
G
K
L
P
G
Site 34
S370
G
N
L
G
A
A
V
S
P
T
S
I
H
T
D
Site 35
S373
G
A
A
V
S
P
T
S
I
H
T
D
K
S
T
Site 36
S379
T
S
I
H
T
D
K
S
T
N
S
P
P
P
K
Site 37
T380
S
I
H
T
D
K
S
T
N
S
P
P
P
K
S
Site 38
S382
H
T
D
K
S
T
N
S
P
P
P
K
S
K
D
Site 39
S387
T
N
S
P
P
P
K
S
K
D
E
V
A
Q
P
Site 40
S398
V
A
Q
P
L
N
L
S
A
K
P
K
T
S
D
Site 41
T403
N
L
S
A
K
P
K
T
S
D
G
K
S
P
T
Site 42
S404
L
S
A
K
P
K
T
S
D
G
K
S
P
T
S
Site 43
S408
P
K
T
S
D
G
K
S
P
T
S
P
T
S
P
Site 44
T410
T
S
D
G
K
S
P
T
S
P
T
S
P
H
M
Site 45
S411
S
D
G
K
S
P
T
S
P
T
S
P
H
M
P
Site 46
T413
G
K
S
P
T
S
P
T
S
P
H
M
P
A
L
Site 47
S414
K
S
P
T
S
P
T
S
P
H
M
P
A
L
R
Site 48
S445
A
S
P
S
A
R
V
S
T
I
G
Y
L
N
D
Site 49
T446
S
P
S
A
R
V
S
T
I
G
Y
L
N
D
H
Site 50
Y449
A
R
V
S
T
I
G
Y
L
N
D
H
D
A
V
Site 51
T494
L
G
L
N
N
C
R
T
E
K
E
K
T
T
L
Site 52
T499
C
R
T
E
K
E
K
T
T
L
E
S
L
T
Q
Site 53
S503
K
E
K
T
T
L
E
S
L
T
Q
Q
L
A
V
Site 54
S519
Q
N
E
E
G
K
F
S
H
A
M
M
D
F
N
Site 55
S528
A
M
M
D
F
N
L
S
G
D
S
D
G
S
A
Site 56
S531
D
F
N
L
S
G
D
S
D
G
S
A
G
V
S
Site 57
S534
L
S
G
D
S
D
G
S
A
G
V
S
E
S
R
Site 58
S538
S
D
G
S
A
G
V
S
E
S
R
I
Y
R
E
Site 59
S540
G
S
A
G
V
S
E
S
R
I
Y
R
E
S
R
Site 60
Y543
G
V
S
E
S
R
I
Y
R
E
S
R
G
R
G
Site 61
S546
E
S
R
I
Y
R
E
S
R
G
R
G
S
N
E
Site 62
S551
R
E
S
R
G
R
G
S
N
E
P
H
I
K
R
Site 63
S584
A
F
P
D
M
H
N
S
N
I
S
K
I
L
G
Site 64
T598
G
S
R
W
K
A
M
T
N
L
E
K
Q
P
Y
Site 65
Y605
T
N
L
E
K
Q
P
Y
Y
E
E
Q
A
R
L
Site 66
Y606
N
L
E
K
Q
P
Y
Y
E
E
Q
A
R
L
S
Site 67
S613
Y
E
E
Q
A
R
L
S
K
Q
H
L
E
K
Y
Site 68
Y620
S
K
Q
H
L
E
K
Y
P
D
Y
K
Y
K
P
Site 69
Y623
H
L
E
K
Y
P
D
Y
K
Y
K
P
R
P
K
Site 70
Y625
E
K
Y
P
D
Y
K
Y
K
P
R
P
K
R
T
Site 71
Y645
K
K
L
R
I
G
E
Y
K
A
I
M
R
N
R
Site 72
Y659
R
R
Q
E
M
R
Q
Y
F
N
V
G
Q
Q
A
Site 73
S688
I
A
M
A
G
M
P
S
P
H
L
P
S
E
H
Site 74
S693
M
P
S
P
H
L
P
S
E
H
S
S
V
S
S
Site 75
S696
P
H
L
P
S
E
H
S
S
V
S
S
S
P
E
Site 76
S697
H
L
P
S
E
H
S
S
V
S
S
S
P
E
P
Site 77
S699
P
S
E
H
S
S
V
S
S
S
P
E
P
G
M
Site 78
S700
S
E
H
S
S
V
S
S
S
P
E
P
G
M
P
Site 79
S701
E
H
S
S
V
S
S
S
P
E
P
G
M
P
V
Site 80
S711
P
G
M
P
V
I
Q
S
T
Y
G
V
K
G
E
Site 81
Y736
E
D
I
N
G
E
I
Y
D
E
Y
D
E
E
E
Site 82
Y739
N
G
E
I
Y
D
E
Y
D
E
E
E
D
D
P
Site 83
Y750
E
D
D
P
D
V
D
Y
G
S
D
S
E
N
H
Site 84
S752
D
P
D
V
D
Y
G
S
D
S
E
N
H
I
A
Site 85
S754
D
V
D
Y
G
S
D
S
E
N
H
I
A
G
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation