PhosphoNET

           
Protein Info 
   
Short Name:  SOX18
Full Name:  Transcription factor SOX-18
Alias:  HLTS; SRY (sex determining region Y)-box 18; SRY-box 18
Type:  Transcription factor
Mass (Da):  40891
Number AA:  384
UniProt ID:  P35713
International Prot ID:  IPI00020428
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0003702  GO:0010843   PhosphoSite+ KinaseNET
Biological Process:  GO:0001525  GO:0043534  GO:0001885 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y8MQRSPPGYGAQDDPP
Site 2S50AAPAAPASPPSPQRS
Site 3S53AAPASPPSPQRSPPR
Site 4S57SPPSPQRSPPRSPEP
Site 5S61PQRSPPRSPEPGRYG
Site 6Y67RSPEPGRYGLSPAGR
Site 7S70EPGRYGLSPAGRGER
Site 8S83ERQAADESRIRRPMN
Site 9Y152HLRDHPNYKYRPRRK
Site 10Y154RDHPNYKYRPRRKKQ
Site 11S191PEPFPAASGSARAFR
Site 12S193PFPAASGSARAFREL
Site 13T214FDGLGLPTPERSPLD
Site 14S218GLPTPERSPLDGLEP
Site 15Y249LRPFRAPYAPTELSR
Site 16S255PYAPTELSRDPGGCY
Site 17Y262SRDPGGCYGAPLAEA
Site 18T289LYYGTLGTPGPYPGP
Site 19Y293TLGTPGPYPGPLSPP
Site 20S298GPYPGPLSPPPEAPP
Site 21S308PEAPPLESAEPLGPA
Site 22T325LWADVDLTEFDQYLN
Site 23Y330DLTEFDQYLNCSRTR
Site 24S334FDQYLNCSRTRPDAP
Site 25T336QYLNCSRTRPDAPGL
Site 26S358KLGPRAMSCPEESSL
Site 27S364MSCPEESSLISALSD
Site 28S367PEESSLISALSDASS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation