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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KRT20
Full Name:
Keratin, type I cytoskeletal 20
Alias:
CK 20; CK20; Cytokeratin 20; Cytokeratin-20; K1C20; Keratin 20; Keratin-20; KRT21; MGC35423; Protein IT
Type:
Cytoskeletal protein
Mass (Da):
48487
Number AA:
424
UniProt ID:
P35900
International Prot ID:
IPI00021298
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005882
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005200
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0045109
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
D
F
S
R
R
S
F
H
R
S
L
S
S
Site 2
S11
S
R
R
S
F
H
R
S
L
S
S
S
L
Q
A
Site 3
S13
R
S
F
H
R
S
L
S
S
S
L
Q
A
P
V
Site 4
S14
S
F
H
R
S
L
S
S
S
L
Q
A
P
V
V
Site 5
S15
F
H
R
S
L
S
S
S
L
Q
A
P
V
V
S
Site 6
T31
V
G
M
Q
R
L
G
T
T
P
S
V
Y
G
G
Site 7
T32
G
M
Q
R
L
G
T
T
P
S
V
Y
G
G
A
Site 8
S34
Q
R
L
G
T
T
P
S
V
Y
G
G
A
G
G
Site 9
Y36
L
G
T
T
P
S
V
Y
G
G
A
G
G
R
G
Site 10
S47
G
G
R
G
I
R
I
S
N
S
R
H
T
V
N
Site 11
S49
R
G
I
R
I
S
N
S
R
H
T
V
N
Y
G
Site 12
T52
R
I
S
N
S
R
H
T
V
N
Y
G
S
D
L
Site 13
Y55
N
S
R
H
T
V
N
Y
G
S
D
L
T
G
G
Site 14
S57
R
H
T
V
N
Y
G
S
D
L
T
G
G
G
D
Site 15
S83
N
L
N
D
R
L
A
S
Y
L
E
K
V
R
T
Site 16
Y84
L
N
D
R
L
A
S
Y
L
E
K
V
R
T
L
Site 17
T90
S
Y
L
E
K
V
R
T
L
E
Q
S
N
S
K
Site 18
S94
K
V
R
T
L
E
Q
S
N
S
K
L
E
V
Q
Site 19
S96
R
T
L
E
Q
S
N
S
K
L
E
V
Q
I
K
Site 20
Y106
E
V
Q
I
K
Q
W
Y
E
T
N
A
P
R
A
Site 21
T108
Q
I
K
Q
W
Y
E
T
N
A
P
R
A
G
R
Site 22
Y117
A
P
R
A
G
R
D
Y
S
A
Y
Y
R
Q
I
Site 23
S118
P
R
A
G
R
D
Y
S
A
Y
Y
R
Q
I
E
Site 24
Y120
A
G
R
D
Y
S
A
Y
Y
R
Q
I
E
E
L
Site 25
Y121
G
R
D
Y
S
A
Y
Y
R
Q
I
E
E
L
R
Site 26
S129
R
Q
I
E
E
L
R
S
Q
I
K
D
A
Q
L
Site 27
Y159
A
E
D
F
R
L
K
Y
E
T
E
R
G
I
R
Site 28
T161
D
F
R
L
K
Y
E
T
E
R
G
I
R
L
T
Site 29
T168
T
E
R
G
I
R
L
T
V
E
A
D
L
Q
G
Site 30
T184
N
K
V
F
D
D
L
T
L
H
K
T
D
L
E
Site 31
T188
D
D
L
T
L
H
K
T
D
L
E
I
Q
I
E
Site 32
T222
L
H
K
H
L
G
N
T
V
N
V
E
V
D
A
Site 33
Y246
M
N
E
M
R
Q
K
Y
E
V
M
A
Q
K
N
Site 34
T265
K
E
Q
F
E
R
Q
T
A
V
L
Q
Q
Q
V
Site 35
T273
A
V
L
Q
Q
Q
V
T
V
N
T
E
E
L
K
Site 36
T282
N
T
E
E
L
K
G
T
E
V
Q
L
T
E
L
Site 37
T287
K
G
T
E
V
Q
L
T
E
L
R
R
T
S
Q
Site 38
T292
Q
L
T
E
L
R
R
T
S
Q
S
L
E
I
E
Site 39
S293
L
T
E
L
R
R
T
S
Q
S
L
E
I
E
L
Site 40
S295
E
L
R
R
T
S
Q
S
L
E
I
E
L
Q
S
Site 41
S302
S
L
E
I
E
L
Q
S
H
L
S
M
K
E
S
Site 42
S305
I
E
L
Q
S
H
L
S
M
K
E
S
L
E
H
Site 43
S309
S
H
L
S
M
K
E
S
L
E
H
T
L
E
E
Site 44
T313
M
K
E
S
L
E
H
T
L
E
E
T
K
A
R
Site 45
S322
E
E
T
K
A
R
Y
S
S
Q
L
A
N
L
Q
Site 46
S323
E
T
K
A
R
Y
S
S
Q
L
A
N
L
Q
S
Site 47
S334
N
L
Q
S
L
L
S
S
L
E
A
Q
L
M
Q
Site 48
Y353
M
E
R
Q
N
N
E
Y
H
I
L
L
D
I
K
Site 49
T361
H
I
L
L
D
I
K
T
R
L
E
Q
E
I
A
Site 50
T369
R
L
E
Q
E
I
A
T
Y
R
R
L
L
E
G
Site 51
Y370
L
E
Q
E
I
A
T
Y
R
R
L
L
E
G
E
Site 52
T381
L
E
G
E
D
V
K
T
T
E
Y
Q
L
S
T
Site 53
Y384
E
D
V
K
T
T
E
Y
Q
L
S
T
L
E
E
Site 54
S387
K
T
T
E
Y
Q
L
S
T
L
E
E
R
D
I
Site 55
T397
E
E
R
D
I
K
K
T
R
K
I
K
T
V
V
Site 56
T402
K
K
T
R
K
I
K
T
V
V
Q
E
V
V
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation