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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSMC2
Full Name:
26S protease regulatory subunit 7
Alias:
Mammalian suppressor of sgv-1 of yeast; MGC3004; MSS1; MSS1 protein; Nbla10058; Protease 26S subunit 7; Proteasome (prosome, macropain) 26S subunit, ATPase, 2; Proteasome 26S ATPase subunit 2; Proteasome 26S subunit ATPase 2; Proteasome 26S subunit, ATPase, 2; Protein MSS1; PRS7; Putative protein product of Nbla10058; S7
Type:
Protease complex protein, 26S protease
Mass (Da):
48634
Number AA:
433
UniProt ID:
P35998
International Prot ID:
IPI00021435
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0000502
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0044419
GO:0051436
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y4
M
P
D
Y
L
G
A
D
Q
R
K
T
K
E
D
Site 2
T12
L
G
A
D
Q
R
K
T
K
E
D
E
K
D
D
Site 3
T35
G
D
I
A
L
L
K
T
Y
G
Q
S
T
Y
S
Site 4
Y41
K
T
Y
G
Q
S
T
Y
S
R
Q
I
K
Q
V
Site 5
T63
L
K
K
I
N
E
L
T
G
I
K
E
S
D
T
Site 6
T70
T
G
I
K
E
S
D
T
G
L
A
P
P
A
L
Site 7
T99
P
L
Q
V
A
R
C
T
K
I
I
N
A
D
S
Site 8
S106
T
K
I
I
N
A
D
S
E
D
P
K
Y
I
I
Site 9
Y111
A
D
S
E
D
P
K
Y
I
I
N
V
K
Q
F
Site 10
Y147
V
G
V
D
R
N
K
Y
Q
I
H
I
P
L
P
Site 11
T160
L
P
P
K
I
D
P
T
V
T
M
M
Q
V
E
Site 12
T173
V
E
E
K
P
D
V
T
Y
S
D
V
G
G
C
Site 13
Y174
E
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
Site 14
S175
E
K
P
D
V
T
Y
S
D
V
G
G
C
K
E
Site 15
T193
K
L
R
E
V
V
E
T
P
L
L
H
P
E
R
Site 16
Y249
G
S
E
L
V
Q
K
Y
V
G
E
G
A
R
M
Site 17
T298
G
D
N
E
V
Q
R
T
M
L
E
L
I
N
Q
Site 18
T321
N
I
K
V
L
M
A
T
N
R
P
D
T
L
D
Site 19
T326
M
A
T
N
R
P
D
T
L
D
P
A
L
M
R
Site 20
S344
L
D
R
K
I
E
F
S
L
P
D
L
E
G
R
Site 21
S361
I
F
K
I
H
A
R
S
M
S
V
E
R
D
I
Site 22
S363
K
I
H
A
R
S
M
S
V
E
R
D
I
R
F
Site 23
S380
L
A
R
L
C
P
N
S
T
G
A
E
I
R
S
Site 24
S387
S
T
G
A
E
I
R
S
V
C
T
E
A
G
M
Site 25
T405
R
A
R
R
K
I
A
T
E
K
D
F
L
E
A
Site 26
T426
S
Y
A
K
F
S
A
T
P
R
Y
M
T
Y
N
Site 27
Y429
K
F
S
A
T
P
R
Y
M
T
Y
N
_
_
_
Site 28
Y432
A
T
P
R
Y
M
T
Y
N
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation