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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Cx40
Full Name:
Gap junction alpha-5 protein
Alias:
Connexin 40; CX40; CXA5; Gap junction protein, alpha 5, 40kDa; GJA5
Type:
Channel, misc.
Mass (Da):
40380
Number AA:
358
UniProt ID:
P36382
International Prot ID:
IPI00217262
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005922
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007043
GO:0006936
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T19
E
E
V
H
K
H
S
T
V
V
G
K
V
W
L
Site 2
Y66
P
G
C
Q
N
V
C
Y
D
Q
A
F
P
I
S
Site 3
S120
R
A
K
E
V
R
G
S
G
S
Y
E
Y
P
V
Site 4
S122
K
E
V
R
G
S
G
S
Y
E
Y
P
V
A
E
Site 5
Y123
E
V
R
G
S
G
S
Y
E
Y
P
V
A
E
K
Site 6
Y125
R
G
S
G
S
Y
E
Y
P
V
A
E
K
A
E
Site 7
S134
V
A
E
K
A
E
L
S
C
W
E
E
G
N
G
Site 8
S188
T
L
H
V
C
R
R
S
P
C
P
H
P
V
N
Site 9
Y197
C
P
H
P
V
N
C
Y
V
S
R
P
T
E
K
Site 10
T202
N
C
Y
V
S
R
P
T
E
K
N
V
F
I
V
Site 11
S260
P
S
V
G
I
V
Q
S
C
T
P
P
P
D
F
Site 12
T262
V
G
I
V
Q
S
C
T
P
P
P
D
F
N
Q
Site 13
S289
P
F
S
N
N
M
A
S
Q
Q
N
T
D
N
L
Site 14
T293
N
M
A
S
Q
Q
N
T
D
N
L
V
T
E
Q
Site 15
T307
Q
V
R
G
Q
E
Q
T
P
G
E
G
F
I
Q
Site 16
Y317
E
G
F
I
Q
V
R
Y
G
Q
K
P
E
V
P
Site 17
S328
P
E
V
P
N
G
V
S
P
G
H
R
L
P
H
Site 18
Y337
G
H
R
L
P
H
G
Y
H
S
D
K
R
R
L
Site 19
S339
R
L
P
H
G
Y
H
S
D
K
R
R
L
S
K
Site 20
S345
H
S
D
K
R
R
L
S
K
A
S
S
K
A
R
Site 21
S348
K
R
R
L
S
K
A
S
S
K
A
R
S
D
D
Site 22
S349
R
R
L
S
K
A
S
S
K
A
R
S
D
D
L
Site 23
S353
K
A
S
S
K
A
R
S
D
D
L
S
V
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation