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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Cx45
Full Name:
Gap junction gamma-1 protein
Alias:
Connexin-45; CXA7; CXG1; Gap junction alpha-7 protein; Gap junction protein, alpha 7, 45kD (connexin 45); Gap junction protein, alpha 7, 45kDa (connexin 45); GJA7
Type:
Adhesion protein
Mass (Da):
45470
Number AA:
396
UniProt ID:
P36383
International Prot ID:
IPI00002946
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005922
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0007043
GO:0006936
GO:0006810
PhosphoSite+
KinaseNET
Biological Process:
GO:0007043
GO:0006936
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y44
A
V
G
G
E
S
I
Y
Y
D
E
Q
S
K
F
Site 2
Y45
V
G
G
E
S
I
Y
Y
D
E
Q
S
K
F
V
Site 3
T130
Q
H
R
A
L
E
E
T
E
E
D
N
E
E
D
Site 4
Y141
N
E
E
D
P
M
M
Y
P
E
M
E
L
E
S
Site 5
S148
Y
P
E
M
E
L
E
S
D
K
E
N
K
E
Q
Site 6
S156
D
K
E
N
K
E
Q
S
Q
P
K
P
K
H
D
Site 7
S261
G
F
G
T
I
R
D
S
L
N
S
K
R
R
E
Site 8
S264
T
I
R
D
S
L
N
S
K
R
R
E
L
E
D
Site 9
Y275
E
L
E
D
P
G
A
Y
N
Y
P
F
T
W
N
Site 10
Y277
E
D
P
G
A
Y
N
Y
P
F
T
W
N
T
P
Site 11
T280
G
A
Y
N
Y
P
F
T
W
N
T
P
S
A
P
Site 12
T283
N
Y
P
F
T
W
N
T
P
S
A
P
P
G
Y
Site 13
Y290
T
P
S
A
P
P
G
Y
N
I
A
V
K
P
D
Site 14
Y301
V
K
P
D
Q
I
Q
Y
T
E
L
S
N
A
K
Site 15
S305
Q
I
Q
Y
T
E
L
S
N
A
K
I
A
Y
K
Site 16
Y324
N
T
A
Q
E
Q
Q
Y
G
S
H
E
E
N
L
Site 17
S326
A
Q
E
Q
Q
Y
G
S
H
E
E
N
L
P
A
Site 18
Y356
L
D
L
A
V
Q
A
Y
S
H
Q
N
N
P
H
Site 19
S374
E
K
K
A
K
V
G
S
K
A
G
S
N
K
S
Site 20
S378
K
V
G
S
K
A
G
S
N
K
S
T
A
S
S
Site 21
S381
S
K
A
G
S
N
K
S
T
A
S
S
K
S
G
Site 22
T382
K
A
G
S
N
K
S
T
A
S
S
K
S
G
D
Site 23
S384
G
S
N
K
S
T
A
S
S
K
S
G
D
G
K
Site 24
S385
S
N
K
S
T
A
S
S
K
S
G
D
G
K
T
Site 25
S387
K
S
T
A
S
S
K
S
G
D
G
K
T
S
V
Site 26
S393
K
S
G
D
G
K
T
S
V
W
I
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation