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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM23
Full Name:
E3 ubiquitin-protein ligase TRIM23
Alias:
ADP-ribosylation factor domain protein 1; ARD1; ARF domain protein 1; ARFD1; RING finger protein 46; RNF46; tripartite motif protein 23; tripartite motif-containing 23
Type:
G protein, monomeric (non-Rab); G protein
Mass (Da):
64070
Number AA:
UniProt ID:
P36406
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000139
GO:0005765
Uniprot
OncoNet
Molecular Function:
GO:0019003
GO:0005525
GO:0003924
PhosphoSite+
KinaseNET
Biological Process:
GO:0016567
GO:0007264
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
K
L
G
A
G
V
D
S
G
R
Q
G
S
R
G
Site 2
S20
V
D
S
G
R
Q
G
S
R
G
T
A
V
V
K
Site 3
T23
G
R
Q
G
S
R
G
T
A
V
V
K
V
L
E
Site 4
S39
G
V
C
E
D
V
F
S
L
Q
G
D
K
V
P
Site 5
T79
C
P
F
D
R
Q
V
T
D
L
G
D
S
G
V
Site 6
S84
Q
V
T
D
L
G
D
S
G
V
W
G
L
K
K
Site 7
S151
T
H
L
C
S
E
C
S
Q
V
T
H
S
T
K
Site 8
T176
A
D
K
P
H
E
K
T
M
C
S
Q
H
Q
V
Site 9
S217
K
H
Q
G
H
K
H
S
V
L
E
P
E
A
N
Site 10
T239
D
M
A
H
C
I
R
T
F
T
E
E
I
S
D
Site 11
T241
A
H
C
I
R
T
F
T
E
E
I
S
D
Y
S
Site 12
S245
R
T
F
T
E
E
I
S
D
Y
S
R
K
L
V
Site 13
Y247
F
T
E
E
I
S
D
Y
S
R
K
L
V
G
I
Site 14
T274
D
G
I
G
M
A
H
T
E
H
V
P
G
T
A
Site 15
Y291
A
R
S
C
I
R
A
Y
F
Y
D
L
H
E
T
Site 16
S308
R
Q
E
E
M
A
L
S
V
V
D
A
H
V
R
Site 17
T329
R
Q
Q
Q
E
D
M
T
I
L
L
S
E
V
S
Site 18
S386
D
H
I
Q
L
D
A
S
I
P
V
T
F
T
K
Site 19
T390
L
D
A
S
I
P
V
T
F
T
K
D
N
R
V
Site 20
T442
T
I
G
F
N
V
E
T
V
E
Y
K
N
L
K
Site 21
Y445
F
N
V
E
T
V
E
Y
K
N
L
K
F
T
I
Site 22
Y468
L
R
P
L
W
K
H
Y
Y
L
N
T
Q
A
V
Site 23
Y469
R
P
L
W
K
H
Y
Y
L
N
T
Q
A
V
V
Site 24
S482
V
V
F
V
V
D
S
S
H
R
D
R
I
S
E
Site 25
S488
S
S
H
R
D
R
I
S
E
A
H
S
E
L
A
Site 26
S492
D
R
I
S
E
A
H
S
E
L
A
K
L
L
T
Site 27
S550
I
Q
G
C
D
A
R
S
G
M
G
L
Y
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation