PhosphoNET

           
Protein Info 
   
Short Name:  UGT2B10
Full Name:  UDP-glucuronosyltransferase 2B10
Alias:  EC 2.4.1.17; UDB10; UDP glucuronosyltransferase 2 family, polypeptide B10
Type:  Lipid Metabolism - androgen and estrogen; Cofactor and Vitamin Metabolism - retinol; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Xenobiotic Metabolism - metabolism by cytochrome P450; Carbohydrate Metabolism - ascorbate and aldarate; EC 2.4.1.17; Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - drug metabolism - other enzymes; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - pentose and glucuronate interconversions
Mass (Da):  60774
Number AA:  528
UniProt ID:  P36537
International Prot ID:  IPI00003836
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005783  GO:0016021  GO:0005792 Uniprot OncoNet
Molecular Function:  GO:0015020     PhosphoSite+ KinaseNET
Biological Process:  GO:0006629     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T53VQRGHEVTVLASSAS
Site 2S68ILFDPNDSSTLKLEV
Site 3S69LFDPNDSSTLKLEVY
Site 4T70FDPNDSSTLKLEVYP
Site 5Y76STLKLEVYPTSLTKT
Site 6T78LKLEVYPTSLTKTEF
Site 7S79KLEVYPTSLTKTEFE
Site 8T83YPTSLTKTEFENIIM
Site 9S97MQLVKRLSEIQKDTF
Site 10T103LSEIQKDTFWLPFSQ
Site 11S174FVYSHSFSPGYSFER
Site 12Y177SHSFSPGYSFERHSG
Site 13S178HSFSPGYSFERHSGG
Site 14S183GYSFERHSGGFIFPP
Site 15Y192GFIFPPSYVPVVMSK
Site 16T205SKLSDQMTFMERVKN
Site 17Y235MKKWDQFYSEVLGRP
Site 18S236KKWDQFYSEVLGRPT
Site 19T243SEVLGRPTTLSETMR
Site 20T244EVLGRPTTLSETMRK
Site 21S246LGRPTTLSETMRKAD
Site 22T248RPTTLSETMRKADIW
Site 23S297EMEEFVQSSGENGVV
Site 24S313FSLGSMVSNMTEERA
Site 25Y353LGLNTRLYKWIPQND
Site 26T367DLLGHPKTRAFITHG
Site 27Y380HGGANGIYEAIYHGI
Site 28S420RVDFNTMSSTDLLNA
Site 29T430DLLNALKTVINDPSY
Site 30S436KTVINDPSYKENIMK
Site 31Y437TVINDPSYKENIMKL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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