KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CPOX
Full Name:
Coproporphyrinogen-III oxidase, mitochondrial
Alias:
Coprogen oxidase; Coproporphyria; Coproporphyrinogen III oxidase, mitochondrial; Coproporphyrinogen oxidase; COX; CPO; CPX; HCP; HEM6
Type:
Oxidoreductase; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 1.3.3.3
Mass (Da):
50152
Number AA:
454
UniProt ID:
P36551
International Prot ID:
IPI00093057
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005758
Uniprot
OncoNet
Molecular Function:
GO:0004109
GO:0042803
PhosphoSite+
KinaseNET
Biological Process:
GO:0006783
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
C
G
G
P
R
A
W
S
Q
C
G
G
G
G
L
Site 2
S39
G
G
G
L
R
A
W
S
Q
R
S
A
A
G
R
Site 3
S66
S
R
G
L
G
H
G
S
T
S
R
G
G
P
W
Site 4
T67
R
G
L
G
H
G
S
T
S
R
G
G
P
W
V
Site 5
S68
G
L
G
H
G
S
T
S
R
G
G
P
W
V
G
Site 6
T105
R
A
E
M
L
P
K
T
S
G
T
R
A
T
S
Site 7
T108
M
L
P
K
T
S
G
T
R
A
T
S
L
G
R
Site 8
T111
K
T
S
G
T
R
A
T
S
L
G
R
P
E
E
Site 9
S112
T
S
G
T
R
A
T
S
L
G
R
P
E
E
E
Site 10
S128
D
E
L
A
H
R
C
S
S
F
M
A
P
P
V
Site 11
S129
E
L
A
H
R
C
S
S
F
M
A
P
P
V
T
Site 12
T136
S
F
M
A
P
P
V
T
D
L
G
E
L
R
R
Site 13
T150
R
R
P
G
D
M
K
T
K
M
E
L
L
I
L
Site 14
S177
V
D
G
G
A
N
F
S
V
D
R
W
E
R
K
Site 15
S191
K
E
G
G
G
G
I
S
C
V
L
Q
D
G
C
Site 16
S215
S
V
V
H
G
N
L
S
E
E
A
A
K
Q
M
Site 17
T231
S
R
G
K
V
L
K
T
K
D
G
K
L
P
F
Site 18
Y263
T
I
H
F
N
Y
R
Y
F
E
V
E
E
A
D
Site 19
T284
F
G
G
G
C
D
L
T
P
T
Y
L
N
Q
E
Site 20
Y287
G
C
D
L
T
P
T
Y
L
N
Q
E
D
A
V
Site 21
Y312
D
Q
H
G
P
D
L
Y
P
K
F
K
K
W
C
Site 22
S344
I
F
F
D
D
L
D
S
P
S
K
E
E
V
F
Site 23
S346
F
D
D
L
D
S
P
S
K
E
E
V
F
R
F
Site 24
S376
V
K
K
H
C
D
D
S
F
T
P
Q
E
K
L
Site 25
Y392
Q
Q
L
R
R
G
R
Y
V
E
F
N
L
L
Y
Site 26
Y399
Y
V
E
F
N
L
L
Y
D
R
G
T
K
F
G
Site 27
T403
N
L
L
Y
D
R
G
T
K
F
G
L
F
T
P
Site 28
T409
G
T
K
F
G
L
F
T
P
G
S
R
I
E
S
Site 29
T424
I
L
M
S
L
P
L
T
A
R
W
E
Y
M
H
Site 30
Y429
P
L
T
A
R
W
E
Y
M
H
S
P
S
E
N
Site 31
S432
A
R
W
E
Y
M
H
S
P
S
E
N
S
K
E
Site 32
S434
W
E
Y
M
H
S
P
S
E
N
S
K
E
A
E
Site 33
S437
M
H
S
P
S
E
N
S
K
E
A
E
I
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation