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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPP1CC
Full Name:
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Alias:
EC 3.1.3.16; PP1G; PP-1G; PPP1G
Type:
Protein-serine phosphatase
Mass (Da):
36984
Number AA:
323
UniProt ID:
P36873
International Prot ID:
IPI00005705
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070688
GO:0005737
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0005506
GO:0030145
GO:0019901
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0051301
GO:0005977
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
R
L
L
E
V
R
G
S
K
P
G
K
N
V
Q
Site 2
S42
I
R
G
L
C
L
K
S
R
E
I
F
L
S
Q
Site 3
S48
K
S
R
E
I
F
L
S
Q
P
I
L
L
E
L
Site 4
Y69
C
G
D
I
H
G
Q
Y
Y
D
L
L
R
L
F
Site 5
Y70
G
D
I
H
G
Q
Y
Y
D
L
L
R
L
F
E
Site 6
Y78
D
L
L
R
L
F
E
Y
G
G
F
P
P
E
S
Site 7
S85
Y
G
G
F
P
P
E
S
N
Y
L
F
L
G
D
Site 8
Y87
G
F
P
P
E
S
N
Y
L
F
L
G
D
Y
V
Site 9
Y93
N
Y
L
F
L
G
D
Y
V
D
R
G
K
Q
S
Site 10
S100
Y
V
D
R
G
K
Q
S
L
E
T
I
C
L
L
Site 11
Y134
C
A
S
I
N
R
I
Y
G
F
Y
D
E
C
K
Site 12
Y137
I
N
R
I
Y
G
F
Y
D
E
C
K
R
R
Y
Site 13
Y144
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Site 14
S177
F
C
C
H
G
G
L
S
P
D
L
Q
S
M
E
Site 15
S182
G
L
S
P
D
L
Q
S
M
E
Q
I
R
R
I
Site 16
T193
I
R
R
I
M
R
P
T
D
V
P
D
Q
G
L
Site 17
S224
G
E
N
D
R
G
V
S
F
T
F
G
A
E
V
Site 18
Y255
H
Q
V
V
E
D
G
Y
E
F
F
A
K
R
Q
Site 19
T265
F
A
K
R
Q
L
V
T
L
F
S
A
P
N
Y
Site 20
S268
R
Q
L
V
T
L
F
S
A
P
N
Y
C
G
E
Site 21
Y272
T
L
F
S
A
P
N
Y
C
G
E
F
D
N
A
Site 22
T307
E
K
K
K
P
N
A
T
R
P
V
T
P
P
R
Site 23
T311
P
N
A
T
R
P
V
T
P
P
R
G
M
I
T
Site 24
T318
T
P
P
R
G
M
I
T
K
Q
A
K
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation