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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GNL1
Full Name:
Guanine nucleotide-binding protein-like 1
Alias:
GTP-binding protein HSR1; Guanine nucleotide binding protein-like 1; HSR1; HSR1 GTP-binding protein
Type:
Unknown function
Mass (Da):
68661
Number AA:
607
UniProt ID:
P36915
International Prot ID:
IPI00006056
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0002456
GO:0006974
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
P
R
K
K
P
F
S
V
K
Q
K
K
K
Q
Site 2
S32
G
L
Q
D
G
L
R
S
S
S
N
S
R
S
G
Site 3
S33
L
Q
D
G
L
R
S
S
S
N
S
R
S
G
S
Site 4
S34
Q
D
G
L
R
S
S
S
N
S
R
S
G
S
R
Site 5
S36
G
L
R
S
S
S
N
S
R
S
G
S
R
E
R
Site 6
S38
R
S
S
S
N
S
R
S
G
S
R
E
R
R
E
Site 7
S40
S
S
N
S
R
S
G
S
R
E
R
R
E
E
Q
Site 8
T48
R
E
R
R
E
E
Q
T
D
T
S
D
G
E
S
Site 9
T50
R
R
E
E
Q
T
D
T
S
D
G
E
S
V
T
Site 10
S51
R
E
E
Q
T
D
T
S
D
G
E
S
V
T
H
Site 11
S55
T
D
T
S
D
G
E
S
V
T
H
H
I
R
R
Site 12
T57
T
S
D
G
E
S
V
T
H
H
I
R
R
L
N
Site 13
S68
R
R
L
N
Q
Q
P
S
Q
G
L
G
P
R
G
Site 14
Y76
Q
G
L
G
P
R
G
Y
D
P
N
R
Y
R
L
Site 15
Y81
R
G
Y
D
P
N
R
Y
R
L
H
F
E
R
D
Site 16
S89
R
L
H
F
E
R
D
S
R
E
E
V
E
R
R
Site 17
Y121
E
L
D
I
R
E
V
Y
Q
P
G
S
V
L
D
Site 18
S125
R
E
V
Y
Q
P
G
S
V
L
D
F
P
R
R
Site 19
S136
F
P
R
R
P
P
W
S
Y
E
M
S
K
E
Q
Site 20
Y137
P
R
R
P
P
W
S
Y
E
M
S
K
E
Q
L
Site 21
S140
P
P
W
S
Y
E
M
S
K
E
Q
L
M
S
Q
Site 22
S146
M
S
K
E
Q
L
M
S
Q
E
E
R
S
F
Q
Site 23
S151
L
M
S
Q
E
E
R
S
F
Q
D
Y
L
G
K
Site 24
Y155
E
E
R
S
F
Q
D
Y
L
G
K
I
H
G
A
Site 25
Y163
L
G
K
I
H
G
A
Y
S
S
E
K
L
S
Y
Site 26
S164
G
K
I
H
G
A
Y
S
S
E
K
L
S
Y
F
Site 27
S165
K
I
H
G
A
Y
S
S
E
K
L
S
Y
F
E
Site 28
S169
A
Y
S
S
E
K
L
S
Y
F
E
H
N
L
E
Site 29
Y170
Y
S
S
E
K
L
S
Y
F
E
H
N
L
E
T
Site 30
Y246
K
H
Y
F
H
Q
H
Y
P
Q
L
H
V
V
L
Site 31
S256
L
H
V
V
L
F
T
S
F
P
R
D
P
R
T
Site 32
T263
S
F
P
R
D
P
R
T
P
Q
D
P
S
S
V
Site 33
S268
P
R
T
P
Q
D
P
S
S
V
L
K
K
S
R
Site 34
S269
R
T
P
Q
D
P
S
S
V
L
K
K
S
R
R
Site 35
S274
P
S
S
V
L
K
K
S
R
R
R
G
R
G
W
Site 36
T282
R
R
R
G
R
G
W
T
R
A
L
G
P
E
Q
Site 37
S305
T
V
G
K
V
D
L
S
S
W
R
E
K
I
A
Site 38
S306
V
G
K
V
D
L
S
S
W
R
E
K
I
A
R
Site 39
T319
A
R
D
V
A
G
A
T
W
G
N
G
S
G
E
Site 40
S324
G
A
T
W
G
N
G
S
G
E
E
E
E
E
E
Site 41
Y356
T
G
P
T
Q
E
R
Y
K
D
G
V
V
T
I
Site 42
S387
L
V
G
R
K
V
V
S
V
S
R
T
P
G
H
Site 43
S389
G
R
K
V
V
S
V
S
R
T
P
G
H
T
R
Site 44
T391
K
V
V
S
V
S
R
T
P
G
H
T
R
Y
F
Site 45
T395
V
S
R
T
P
G
H
T
R
Y
F
Q
T
Y
F
Site 46
Y397
R
T
P
G
H
T
R
Y
F
Q
T
Y
F
L
T
Site 47
T400
G
H
T
R
Y
F
Q
T
Y
F
L
T
P
S
V
Site 48
Y401
H
T
R
Y
F
Q
T
Y
F
L
T
P
S
V
K
Site 49
T442
A
Q
I
Q
E
P
Y
T
A
V
G
Y
L
A
S
Site 50
Y488
A
W
A
E
K
R
G
Y
K
T
A
K
A
A
R
Site 51
Y499
K
A
A
R
N
D
V
Y
R
A
A
N
S
L
L
Site 52
Y523
L
C
F
H
P
P
G
Y
S
E
Q
K
G
T
W
Site 53
T529
G
Y
S
E
Q
K
G
T
W
E
S
H
P
E
T
Site 54
S532
E
Q
K
G
T
W
E
S
H
P
E
T
T
E
L
Site 55
T536
T
W
E
S
H
P
E
T
T
E
L
V
V
L
Q
Site 56
S561
E
E
E
E
E
E
L
S
S
S
C
E
E
E
G
Site 57
S562
E
E
E
E
E
L
S
S
S
C
E
E
E
G
E
Site 58
S563
E
E
E
E
L
S
S
S
C
E
E
E
G
E
E
Site 59
T584
E
G
E
G
D
E
E
T
P
T
S
A
P
G
S
Site 60
T586
E
G
D
E
E
T
P
T
S
A
P
G
S
S
L
Site 61
S587
G
D
E
E
T
P
T
S
A
P
G
S
S
L
A
Site 62
S591
T
P
T
S
A
P
G
S
S
L
A
G
R
N
P
Site 63
S592
P
T
S
A
P
G
S
S
L
A
G
R
N
P
Y
Site 64
Y599
S
L
A
G
R
N
P
Y
A
L
L
G
E
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation