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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SERPINB5
Full Name:
Serpin B5
Alias:
Protease inhibitor 5
Type:
Mass (Da):
42082
Number AA:
375
UniProt ID:
P36952
International Prot ID:
IPI00783625
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0004857
GO:0004866
GO:0004867
PhosphoSite+
KinaseNET
Biological Process:
GO:0006928
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
D
A
L
Q
L
A
N
S
A
F
A
V
D
L
F
Site 2
T50
Q
V
G
A
K
G
D
T
A
N
E
I
G
Q
V
Site 3
T72
D
V
P
F
G
F
Q
T
V
T
S
D
V
N
K
Site 4
S75
F
G
F
Q
T
V
T
S
D
V
N
K
L
S
S
Site 5
S81
T
S
D
V
N
K
L
S
S
F
Y
S
L
K
L
Site 6
S82
S
D
V
N
K
L
S
S
F
Y
S
L
K
L
I
Site 7
S85
N
K
L
S
S
F
Y
S
L
K
L
I
K
R
L
Site 8
S97
K
R
L
Y
V
D
K
S
L
N
L
S
T
E
F
Site 9
S101
V
D
K
S
L
N
L
S
T
E
F
I
S
S
T
Site 10
T102
D
K
S
L
N
L
S
T
E
F
I
S
S
T
K
Site 11
S106
N
L
S
T
E
F
I
S
S
T
K
R
P
Y
A
Site 12
S107
L
S
T
E
F
I
S
S
T
K
R
P
Y
A
K
Site 13
T108
S
T
E
F
I
S
S
T
K
R
P
Y
A
K
E
Site 14
Y112
I
S
S
T
K
R
P
Y
A
K
E
L
E
T
V
Site 15
T118
P
Y
A
K
E
L
E
T
V
D
F
K
D
K
L
Site 16
S135
T
K
G
Q
I
N
N
S
I
K
D
L
T
D
G
Site 17
T140
N
N
S
I
K
D
L
T
D
G
H
F
E
N
I
Site 18
S152
E
N
I
L
A
D
N
S
V
N
D
Q
T
K
I
Site 19
T157
D
N
S
V
N
D
Q
T
K
I
L
V
V
N
A
Site 20
S176
G
K
W
M
K
K
F
S
E
S
E
T
K
E
C
Site 21
T180
K
K
F
S
E
S
E
T
K
E
C
P
F
R
V
Site 22
T192
F
R
V
N
K
T
D
T
K
P
V
Q
M
M
N
Site 23
S240
P
K
D
V
E
D
E
S
T
G
L
E
K
I
E
Site 24
T241
K
D
V
E
D
E
S
T
G
L
E
K
I
E
K
Site 25
S252
K
I
E
K
Q
L
N
S
E
S
L
S
Q
W
T
Site 26
S254
E
K
Q
L
N
S
E
S
L
S
Q
W
T
N
P
Site 27
S256
Q
L
N
S
E
S
L
S
Q
W
T
N
P
S
T
Site 28
T263
S
Q
W
T
N
P
S
T
M
A
N
A
K
V
K
Site 29
S298
L
G
L
K
H
I
F
S
E
D
T
S
D
F
S
Site 30
T301
K
H
I
F
S
E
D
T
S
D
F
S
G
M
S
Site 31
S302
H
I
F
S
E
D
T
S
D
F
S
G
M
S
E
Site 32
S305
S
E
D
T
S
D
F
S
G
M
S
E
T
K
G
Site 33
S308
T
S
D
F
S
G
M
S
E
T
K
G
V
A
L
Site 34
T310
D
F
S
G
M
S
E
T
K
G
V
A
L
S
N
Site 35
S316
E
T
K
G
V
A
L
S
N
V
I
H
K
V
C
Site 36
S333
I
T
E
D
G
G
D
S
I
E
V
P
G
A
R
Site 37
Y356
N
A
D
H
P
F
I
Y
I
I
R
H
N
K
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation