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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DLST
Full Name:
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
Alias:
2-oxoglutarate dehydrogenase complex component E2;Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex;E2K
Type:
Mass (Da):
48729
Number AA:
453
UniProt ID:
P36957
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
L
S
R
S
R
C
V
S
R
A
F
S
R
S
L
Site 2
S13
R
C
V
S
R
A
F
S
R
S
L
S
A
F
Q
Site 3
S15
V
S
R
A
F
S
R
S
L
S
A
F
Q
K
G
Site 4
S17
R
A
F
S
R
S
L
S
A
F
Q
K
G
N
C
Site 5
S35
R
R
S
L
P
G
V
S
L
C
Q
G
P
G
Y
Site 6
Y42
S
L
C
Q
G
P
G
Y
P
N
S
R
K
V
V
Site 7
S45
Q
G
P
G
Y
P
N
S
R
K
V
V
I
N
N
Site 8
T63
S
V
R
F
F
R
T
T
A
V
C
K
D
D
L
Site 9
S81
K
T
P
A
F
A
E
S
V
T
E
G
D
V
R
Site 10
T96
W
E
K
A
V
G
D
T
V
A
E
D
E
V
V
Site 11
T111
C
E
I
E
T
D
K
T
S
V
Q
V
P
S
P
Site 12
S112
E
I
E
T
D
K
T
S
V
Q
V
P
S
P
A
Site 13
S117
K
T
S
V
Q
V
P
S
P
A
N
G
V
I
E
Site 14
T138
G
G
K
V
E
G
G
T
P
L
F
T
L
R
K
Site 15
T142
E
G
G
T
P
L
F
T
L
R
K
T
G
A
A
Site 16
T146
P
L
F
T
L
R
K
T
G
A
A
P
A
K
A
Site 17
T182
P
P
A
A
P
I
P
T
Q
M
P
P
V
P
S
Site 18
S189
T
Q
M
P
P
V
P
S
P
S
Q
P
P
S
G
Site 19
S191
M
P
P
V
P
S
P
S
Q
P
P
S
G
K
P
Site 20
S195
P
S
P
S
Q
P
P
S
G
K
P
V
S
A
V
Site 21
S200
P
P
S
G
K
P
V
S
A
V
K
P
T
V
A
Site 22
S221
G
A
G
K
G
L
R
S
E
H
R
E
K
M
N
Site 23
T244
R
L
K
E
A
Q
N
T
C
A
M
L
T
T
F
Site 24
S282
N
L
K
L
G
F
M
S
A
F
V
K
A
S
A
Site 25
T305
V
N
A
V
I
D
D
T
T
K
E
V
V
Y
R
Site 26
T306
N
A
V
I
D
D
T
T
K
E
V
V
Y
R
D
Site 27
S318
Y
R
D
Y
I
D
I
S
V
A
V
A
T
P
R
Site 28
T348
A
D
I
E
R
T
I
T
E
L
G
E
K
A
R
Site 29
T368
I
E
D
M
D
G
G
T
F
T
I
S
N
G
G
Site 30
T434
I
D
G
R
E
A
V
T
F
L
R
K
I
K
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation