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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GMPR
Full Name:
GMP reductase 1
Alias:
EC 1.7.1.7; GMPR1; Guanosine 5'-monophosphate oxidoreductase 1; Guanosine monophosphate reductase; Guanosine monophosphate reductase 1
Type:
Nucleotide Metabolism - purine; EC 1.7.1.7; Oxidoreductase
Mass (Da):
37419
Number AA:
345
UniProt ID:
P36959
International Prot ID:
IPI00304803
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003920
GO:0030955
PhosphoSite+
KinaseNET
Biological Process:
GO:0009117
GO:0055114
GO:0009409
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
V
L
L
R
P
K
R
S
S
L
K
S
R
A
E
Site 2
S23
L
L
R
P
K
R
S
S
L
K
S
R
A
E
V
Site 3
S26
P
K
R
S
S
L
K
S
R
A
E
V
D
L
E
Site 4
T35
A
E
V
D
L
E
R
T
F
T
F
R
N
S
K
Site 5
T37
V
D
L
E
R
T
F
T
F
R
N
S
K
Q
T
Site 6
S41
R
T
F
T
F
R
N
S
K
Q
T
Y
S
G
I
Site 7
T44
T
F
R
N
S
K
Q
T
Y
S
G
I
P
I
I
Site 8
S81
T
A
I
H
K
H
Y
S
L
D
D
W
K
L
F
Site 9
S115
N
D
L
E
K
M
T
S
I
L
E
A
V
P
Q
Site 10
S184
K
V
G
V
G
P
G
S
V
C
T
T
R
T
K
Site 11
T187
V
G
P
G
S
V
C
T
T
R
T
K
T
G
V
Site 12
T188
G
P
G
S
V
C
T
T
R
T
K
T
G
V
G
Site 13
T192
V
C
T
T
R
T
K
T
G
V
G
Y
P
Q
L
Site 14
Y196
R
T
K
T
G
V
G
Y
P
Q
L
S
A
V
I
Site 15
Y267
G
R
K
L
K
L
F
Y
G
M
S
S
D
T
A
Site 16
S270
L
K
L
F
Y
G
M
S
S
D
T
A
M
N
K
Site 17
S271
K
L
F
Y
G
M
S
S
D
T
A
M
N
K
H
Site 18
Y285
H
A
G
G
V
A
E
Y
R
A
S
E
G
K
T
Site 19
S288
G
V
A
E
Y
R
A
S
E
G
K
T
V
E
V
Site 20
T292
Y
R
A
S
E
G
K
T
V
E
V
P
Y
K
G
Site 21
Y318
G
L
R
S
T
C
T
Y
V
G
A
A
K
L
K
Site 22
S328
A
A
K
L
K
E
L
S
R
R
A
T
F
I
R
Site 23
T332
K
E
L
S
R
R
A
T
F
I
R
V
T
Q
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation