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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPAR-gamma-1
Full Name:
Peroxisome proliferator-activated receptor gamma
Alias:
Nuclear receptor subfamily 1 group C member 3
Type:
Transcription protein (receptor)
Mass (Da):
57620
Number AA:
505
UniProt ID:
P37231
International Prot ID:
IPI00020897
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0050544
GO:0008144
GO:0004955
PhosphoSite+
KinaseNET
Biological Process:
GO:0045165
GO:0048469
GO:0032869
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
G
E
T
L
G
D
S
P
I
D
P
E
S
D
Site 2
S14
D
S
P
I
D
P
E
S
D
S
F
T
D
T
L
Site 3
S16
P
I
D
P
E
S
D
S
F
T
D
T
L
S
A
Site 4
T18
D
P
E
S
D
S
F
T
D
T
L
S
A
N
I
Site 5
T20
E
S
D
S
F
T
D
T
L
S
A
N
I
S
Q
Site 6
S22
D
S
F
T
D
T
L
S
A
N
I
S
Q
E
M
Site 7
S26
D
T
L
S
A
N
I
S
Q
E
M
T
M
V
D
Site 8
T30
A
N
I
S
Q
E
M
T
M
V
D
T
E
M
P
Site 9
S51
G
I
S
S
V
D
L
S
V
M
E
D
H
S
H
Site 10
S57
L
S
V
M
E
D
H
S
H
S
F
D
I
K
P
Site 11
S59
V
M
E
D
H
S
H
S
F
D
I
K
P
F
T
Site 12
S71
P
F
T
T
V
D
F
S
S
I
S
T
P
H
Y
Site 13
S72
F
T
T
V
D
F
S
S
I
S
T
P
H
Y
E
Site 14
T75
V
D
F
S
S
I
S
T
P
H
Y
E
D
I
P
Site 15
Y78
S
S
I
S
T
P
H
Y
E
D
I
P
F
T
R
Site 16
Y93
T
D
P
V
V
A
D
Y
K
Y
D
L
K
L
Q
Site 17
Y95
P
V
V
A
D
Y
K
Y
D
L
K
L
Q
E
Y
Site 18
Y102
Y
D
L
K
L
Q
E
Y
Q
S
A
I
K
V
E
Site 19
S104
L
K
L
Q
E
Y
Q
S
A
I
K
V
E
P
A
Site 20
S112
A
I
K
V
E
P
A
S
P
P
Y
Y
S
E
K
Site 21
Y115
V
E
P
A
S
P
P
Y
Y
S
E
K
T
Q
L
Site 22
Y116
E
P
A
S
P
P
Y
Y
S
E
K
T
Q
L
Y
Site 23
S117
P
A
S
P
P
Y
Y
S
E
K
T
Q
L
Y
N
Site 24
Y123
Y
S
E
K
T
Q
L
Y
N
K
P
H
E
E
P
Site 25
S131
N
K
P
H
E
E
P
S
N
S
L
M
A
I
E
Site 26
S133
P
H
E
E
P
S
N
S
L
M
A
I
E
C
R
Site 27
S147
R
V
C
G
D
K
A
S
G
F
H
Y
G
V
H
Site 28
Y151
D
K
A
S
G
F
H
Y
G
V
H
A
C
E
G
Site 29
T166
C
K
G
F
F
R
R
T
I
R
L
K
L
I
Y
Site 30
Y173
T
I
R
L
K
L
I
Y
D
R
C
D
L
N
C
Site 31
Y192
K
S
R
N
K
C
Q
Y
C
R
F
Q
K
C
L
Site 32
S226
E
K
L
L
A
E
I
S
S
D
I
D
Q
L
N
Site 33
S227
K
L
L
A
E
I
S
S
D
I
D
Q
L
N
P
Site 34
Y247
R
A
L
A
K
H
L
Y
D
S
Y
I
K
S
F
Site 35
S249
L
A
K
H
L
Y
D
S
Y
I
K
S
F
P
L
Site 36
Y250
A
K
H
L
Y
D
S
Y
I
K
S
F
P
L
T
Site 37
S253
L
Y
D
S
Y
I
K
S
F
P
L
T
K
A
K
Site 38
T257
Y
I
K
S
F
P
L
T
K
A
K
A
R
A
I
Site 39
T269
R
A
I
L
T
G
K
T
T
D
K
S
P
F
V
Site 40
S273
T
G
K
T
T
D
K
S
P
F
V
I
Y
D
M
Site 41
Y278
D
K
S
P
F
V
I
Y
D
M
N
S
L
M
M
Site 42
T296
K
I
K
F
K
H
I
T
P
L
Q
E
Q
S
K
Site 43
Y327
A
V
Q
E
I
T
E
Y
A
K
S
I
P
G
F
Site 44
T344
L
D
L
N
D
Q
V
T
L
L
K
Y
G
V
H
Site 45
S370
N
K
D
G
V
L
I
S
E
G
Q
G
F
M
T
Site 46
S383
M
T
R
E
F
L
K
S
L
R
K
P
F
G
D
Site 47
S456
L
K
L
N
H
P
E
S
S
Q
L
F
A
K
L
Site 48
T475
T
D
L
R
Q
I
V
T
E
H
V
Q
L
L
Q
Site 49
T487
L
L
Q
V
I
K
K
T
E
T
D
M
S
L
H
Site 50
S492
K
K
T
E
T
D
M
S
L
H
P
L
L
Q
E
Site 51
Y501
H
P
L
L
Q
E
I
Y
K
D
L
Y
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation