PhosphoNET

           
Protein Info 
   
Short Name:  ATP6V1A
Full Name:  V-type proton ATPase catalytic subunit A
Alias:  ATP6A1; ATP6V1A1; ATPase, H+ transporting, lysosomal 70kD, V1 subunit A, isoform 1; ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A, isoform 1; ATPase, H+ transporting, lysosomal, alpha polypeptide, 70kD, isoform 1; ATPase, H+ transporting, lysosomal, subunit A1; EC 3.6.3.14; H(+)-transporting two-sector ATPase, subunit A; H+-transporting ATPase chain A, vacuolar (VA68 type); HO68; VA68; Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform; Vacuolar ATPase isoform VA68; Vacuolar proton pump alpha subunit 1; VATA; VATA1; V-ATPase 69 kDa subunit 1; V-ATPase A subunit 1; Vma1; VPP2
Type:  Enzyme, hydrolase, energy metabolism group, oxidative phosphorylation family
Mass (Da):  68304
Number AA:  617
UniProt ID:  P38606
International Prot ID:  IPI00007682
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005887  GO:0033180 Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0046933  GO:0046961 PhosphoSite+ KinaseNET
Biological Process:  GO:0015986     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S16ILDEDKESTFGYVHG
Site 2T17LDEDKESTFGYVHGV
Site 3Y20DKESTFGYVHGVSGP
Site 4Y67DMATIQVYEETSGVS
Site 5T82VGDPVLRTGKPLSVE
Site 6S107DGIQRPLSDISSQTQ
Site 7S111RPLSDISSQTQSIYI
Site 8S115DISSQTQSIYIPRGV
Site 9Y117SSQTQSIYIPRGVNV
Site 10S125IPRGVNVSALSRDIK
Site 11S128GVNVSALSRDIKWDF
Site 12T136RDIKWDFTPCKNLRV
Site 13S145CKNLRVGSHITGGDI
Site 14T148LRVGSHITGGDIYGI
Site 15Y153HITGGDIYGIVSENS
Site 16S160YGIVSENSLIKHKIM
Site 17T175LPPRNRGTVTYIAPP
Site 18T177PRNRGTVTYIAPPGN
Site 19Y178RNRGTVTYIAPPGNY
Site 20T187APPGNYDTSDVVLEL
Site 21S188PPGNYDTSDVVLELE
Site 22T218VRQVRPVTEKLPANH
Site 23T229PANHPLLTGQRVLDA
Site 24S260GCGKTVISQSLSKYS
Site 25S262GKTVISQSLSKYSNS
Site 26S264TVISQSLSKYSNSDV
Site 27Y266ISQSLSKYSNSDVII
Site 28S267SQSLSKYSNSDVIIY
Site 29Y274SNSDVIIYVGCGERG
Site 30S285GERGNEMSEVLRDFP
Site 31T295LRDFPELTMEVDGKV
Site 32S304EVDGKVESIMKRTAL
Site 33S316TALVANTSNMPVAAR
Site 34Y328AAREASIYTGITLSE
Site 35Y336TGITLSEYFRDMGYH
Site 36Y342EYFRDMGYHVSMMAD
Site 37S350HVSMMADSTSRWAEA
Site 38T351VSMMADSTSRWAEAL
Site 39S352SMMADSTSRWAEALR
Site 40S362AEALREISGRLAEMP
Site 41S372LAEMPADSGYPAYLG
Site 42Y374EMPADSGYPAYLGAR
Site 43Y377ADSGYPAYLGARLAS
Site 44S384YLGARLASFYERAGR
Site 45Y386GARLASFYERAGRVK
Site 46S403GNPEREGSVSIVGAV
Site 47S405PEREGSVSIVGAVSP
Site 48S418SPPGGDFSDPVTSAT
Site 49Y454SVNWLISYSKYMRAL
Site 50Y457WLISYSKYMRALDEY
Site 51Y464YMRALDEYYDKHFTE
Site 52Y465MRALDEYYDKHFTEF
Site 53T504GKASLAETDKITLEV
Site 54Y525DFLQQNGYTPYDRFC
Site 55Y528QQNGYTPYDRFCPFY
Site 56Y535YDRFCPFYKTVGMLS
Site 57T557MARRAVETTAQSDNK
Site 58Y579EHMGDILYKLSSMKF
Site 59S582GDILYKLSSMKFKDP
Site 60S583DILYKLSSMKFKDPL
Site 61S599DGEAKIKSDYAQLLE
Site 62Y601EAKIKSDYAQLLEDM
Site 63S614DMQNAFRSLED____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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