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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HSPA9
Full Name:
Stress-70 protein, mitochondrial
Alias:
75 kDa glucose regulated protein; CSA; GRP 75; GRP75; Heat shock 70kDa protein 9; Mortalin; MOT; MOT2; Mot-2; Mthsp75; PBP74; Peptide-binding protein 74; Stress-70 protein, mitochondrial
Type:
Chaperone protein
Mass (Da):
73680
Number AA:
679
UniProt ID:
P38646
International Prot ID:
IPI00007765
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0042645
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0006457
Phosida
TranscriptoNet
STRING
Kinexus Products
Stress-70 protein, mitochondrial pan-specific antibody AB-NN047-2#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN047-2
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
I
S
A
S
R
A
A
A
A
Site 2
S5
_
_
_
M
I
S
A
S
R
A
A
A
A
R
L
Site 3
T22
A
A
A
S
R
G
P
T
A
A
R
H
Q
D
S
Site 4
S29
T
A
A
R
H
Q
D
S
W
N
G
L
S
H
E
Site 5
S42
H
E
A
F
R
L
V
S
R
R
D
Y
A
S
E
Site 6
Y46
R
L
V
S
R
R
D
Y
A
S
E
A
I
K
G
Site 7
S48
V
S
R
R
D
Y
A
S
E
A
I
K
G
A
V
Site 8
T62
V
V
G
I
D
L
G
T
T
N
S
C
V
A
V
Site 9
T63
V
G
I
D
L
G
T
T
N
S
C
V
A
V
M
Site 10
S65
I
D
L
G
T
T
N
S
C
V
A
V
M
E
G
Site 11
T86
E
N
A
E
G
A
R
T
T
P
S
V
V
A
F
Site 12
T87
N
A
E
G
A
R
T
T
P
S
V
V
A
F
T
Site 13
S89
E
G
A
R
T
T
P
S
V
V
A
F
T
A
D
Site 14
T111
P
A
K
R
Q
A
V
T
N
P
N
N
T
F
Y
Site 15
T116
A
V
T
N
P
N
N
T
F
Y
A
T
K
R
L
Site 16
Y118
T
N
P
N
N
T
F
Y
A
T
K
R
L
I
G
Site 17
T120
P
N
N
T
F
Y
A
T
K
R
L
I
G
R
R
Site 18
Y128
K
R
L
I
G
R
R
Y
D
D
P
E
V
Q
K
Site 19
S148
P
F
K
I
V
R
A
S
N
G
D
A
W
V
E
Site 20
Y161
V
E
A
H
G
K
L
Y
S
P
S
Q
I
G
A
Site 21
S162
E
A
H
G
K
L
Y
S
P
S
Q
I
G
A
F
Site 22
T177
V
L
M
K
M
K
E
T
A
E
N
Y
L
G
H
Site 23
Y196
A
V
I
T
V
P
A
Y
F
N
D
S
Q
R
Q
Site 24
S200
V
P
A
Y
F
N
D
S
Q
R
Q
A
T
K
D
Site 25
T205
N
D
S
Q
R
Q
A
T
K
D
A
G
Q
I
S
Site 26
S212
T
K
D
A
G
Q
I
S
G
L
N
V
L
R
V
Site 27
S253
G
G
G
T
F
D
I
S
I
L
E
I
Q
K
G
Site 28
S266
K
G
V
F
E
V
K
S
T
N
G
D
T
F
L
Site 29
T267
G
V
F
E
V
K
S
T
N
G
D
T
F
L
G
Site 30
T271
V
K
S
T
N
G
D
T
F
L
G
G
E
D
F
Site 31
T294
V
K
E
F
K
R
E
T
G
V
D
L
T
K
D
Site 32
T299
R
E
T
G
V
D
L
T
K
D
N
M
A
L
Q
Site 33
S320
E
K
A
K
C
E
L
S
S
S
V
Q
T
D
I
Site 34
S322
A
K
C
E
L
S
S
S
V
Q
T
D
I
N
L
Site 35
T325
E
L
S
S
S
V
Q
T
D
I
N
L
P
Y
L
Site 36
Y331
Q
T
D
I
N
L
P
Y
L
T
M
D
S
S
G
Site 37
T333
D
I
N
L
P
Y
L
T
M
D
S
S
G
P
K
Site 38
S336
L
P
Y
L
T
M
D
S
S
G
P
K
H
L
N
Site 39
S337
P
Y
L
T
M
D
S
S
G
P
K
H
L
N
M
Site 40
T347
K
H
L
N
M
K
L
T
R
A
Q
F
E
G
I
Site 41
T356
A
Q
F
E
G
I
V
T
D
L
I
R
R
T
I
Site 42
T362
V
T
D
L
I
R
R
T
I
A
P
C
Q
K
A
Site 43
S378
Q
D
A
E
V
S
K
S
D
I
G
E
V
I
L
Site 44
T390
V
I
L
V
G
G
M
T
R
M
P
K
V
Q
Q
Site 45
T398
R
M
P
K
V
Q
Q
T
V
Q
D
L
F
G
R
Site 46
S408
D
L
F
G
R
A
P
S
K
A
V
N
P
D
E
Site 47
T462
T
K
L
I
N
R
N
T
T
I
P
T
K
K
S
Site 48
T463
K
L
I
N
R
N
T
T
I
P
T
K
K
S
Q
Site 49
S469
T
T
I
P
T
K
K
S
Q
V
F
S
T
A
A
Site 50
S473
T
K
K
S
Q
V
F
S
T
A
A
D
G
Q
T
Site 51
T504
N
K
L
L
G
Q
F
T
L
I
G
I
P
P
A
Site 52
S533
A
N
G
I
V
H
V
S
A
K
D
K
G
T
G
Site 53
T539
V
S
A
K
D
K
G
T
G
R
E
Q
Q
I
V
Site 54
S549
E
Q
Q
I
V
I
Q
S
S
G
G
L
S
K
D
Site 55
S554
I
Q
S
S
G
G
L
S
K
D
D
I
E
N
M
Site 56
Y568
M
V
K
N
A
E
K
Y
A
E
E
D
R
R
K
Site 57
T592
A
E
G
I
I
H
D
T
E
T
K
M
E
E
F
Site 58
T594
G
I
I
H
D
T
E
T
K
M
E
E
F
K
D
Site 59
S616
N
K
L
K
E
E
I
S
K
M
R
E
L
L
A
Site 60
S627
E
L
L
A
R
K
D
S
E
T
G
E
N
I
R
Site 61
T629
L
A
R
K
D
S
E
T
G
E
N
I
R
Q
A
Site 62
S638
E
N
I
R
Q
A
A
S
S
L
Q
Q
A
S
L
Site 63
S639
N
I
R
Q
A
A
S
S
L
Q
Q
A
S
L
K
Site 64
Y652
L
K
L
F
E
M
A
Y
K
K
M
A
S
E
R
Site 65
S657
M
A
Y
K
K
M
A
S
E
R
E
G
S
G
S
Site 66
S662
M
A
S
E
R
E
G
S
G
S
S
G
T
G
E
Site 67
S664
S
E
R
E
G
S
G
S
S
G
T
G
E
Q
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation