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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IGHMBP2
Full Name:
DNA-binding protein SMUBP-2
Alias:
ATP-dependent helicase IGHMBP2; Cardiac transcription factor 1; CATF1; DNA-binding protein SMUBP-2; EC 3.6.1.-; GF-1; Glial factor 1; HCSA; HMN6; Immunoglobulin mu binding protein 2; SMARD1; SMBP2; SMUBP2; SMUBP-2
Type:
EC 3.6.1.-; Helicase
Mass (Da):
109123
Number AA:
993
UniProt ID:
P38935
International Prot ID:
IPI00009379
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030424
GO:0005737
GO:0030426
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0043141
GO:0032575
PhosphoSite+
KinaseNET
Biological Process:
GO:0006310
GO:0006281
GO:0006260
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
A
E
V
E
E
R
R
S
W
Q
E
N
I
S
L
Site 2
S36
R
S
W
Q
E
N
I
S
L
K
E
L
Q
S
R
Site 3
S54
L
L
K
L
Q
V
S
S
Q
R
T
G
L
Y
G
Site 4
Y60
S
S
Q
R
T
G
L
Y
G
R
L
L
V
T
F
Site 5
T66
L
Y
G
R
L
L
V
T
F
E
P
R
R
Y
G
Site 6
Y72
V
T
F
E
P
R
R
Y
G
S
A
A
A
L
P
Site 7
S74
F
E
P
R
R
Y
G
S
A
A
A
L
P
S
N
Site 8
S80
G
S
A
A
A
L
P
S
N
S
F
T
S
G
D
Site 9
Y92
S
G
D
I
V
G
L
Y
D
A
A
N
E
G
S
Site 10
S113
L
T
R
V
T
Q
K
S
V
T
V
A
F
D
E
Site 11
S127
E
S
H
D
F
Q
L
S
L
D
R
E
N
S
Y
Site 12
S133
L
S
L
D
R
E
N
S
Y
R
L
L
K
L
A
Site 13
T144
L
K
L
A
N
D
V
T
Y
R
R
L
K
K
A
Site 14
Y145
K
L
A
N
D
V
T
Y
R
R
L
K
K
A
L
Site 15
Y158
A
L
I
A
L
K
K
Y
H
S
G
P
A
S
S
Site 16
S177
L
F
G
R
S
A
P
S
P
A
S
E
I
H
P
Site 17
S180
R
S
A
P
S
P
A
S
E
I
H
P
L
T
F
Site 18
T190
H
P
L
T
F
F
N
T
C
L
D
T
S
Q
K
Site 19
S195
F
N
T
C
L
D
T
S
Q
K
E
A
V
S
F
Site 20
S201
T
S
Q
K
E
A
V
S
F
A
L
S
Q
K
E
Site 21
T218
I
I
H
G
P
P
G
T
G
K
T
T
T
V
V
Site 22
S274
H
P
A
R
L
L
E
S
I
Q
Q
H
S
L
D
Site 23
S279
L
E
S
I
Q
Q
H
S
L
D
A
V
L
A
R
Site 24
S317
T
Q
D
K
R
E
K
S
N
F
R
N
E
I
K
Site 25
T408
H
K
Q
L
P
P
T
T
V
S
H
K
A
A
L
Site 26
S410
Q
L
P
P
T
T
V
S
H
K
A
A
L
A
G
Site 27
Y430
M
E
R
L
A
E
E
Y
G
A
R
V
V
R
T
Site 28
T439
A
R
V
V
R
T
L
T
V
Q
Y
R
M
H
Q
Site 29
Y457
R
W
A
S
D
T
M
Y
L
G
Q
L
T
A
H
Site 30
T462
T
M
Y
L
G
Q
L
T
A
H
S
S
V
A
R
Site 31
S466
G
Q
L
T
A
H
S
S
V
A
R
H
L
L
R
Site 32
S508
L
E
E
E
D
E
Q
S
K
G
N
P
G
E
V
Site 33
S551
Q
V
D
L
L
R
Q
S
L
V
H
R
H
P
E
Site 34
S563
H
P
E
L
E
I
K
S
V
D
G
F
Q
G
R
Site 35
S578
E
K
E
A
V
I
L
S
F
V
R
S
N
R
K
Site 36
S582
V
I
L
S
F
V
R
S
N
R
K
G
E
V
G
Site 37
Y642
E
V
R
T
A
F
E
Y
L
D
D
I
V
P
E
Site 38
S652
D
I
V
P
E
N
Y
S
H
E
N
S
Q
G
S
Site 39
S656
E
N
Y
S
H
E
N
S
Q
G
S
S
H
A
A
Site 40
S660
H
E
N
S
Q
G
S
S
H
A
A
T
K
P
Q
Site 41
T664
Q
G
S
S
H
A
A
T
K
P
Q
G
P
A
T
Site 42
T671
T
K
P
Q
G
P
A
T
S
T
R
T
G
S
Q
Site 43
S672
K
P
Q
G
P
A
T
S
T
R
T
G
S
Q
R
Site 44
T673
P
Q
G
P
A
T
S
T
R
T
G
S
Q
R
Q
Site 45
T675
G
P
A
T
S
T
R
T
G
S
Q
R
Q
E
G
Site 46
S677
A
T
S
T
R
T
G
S
Q
R
Q
E
G
G
Q
Site 47
S701
R
K
K
P
A
G
K
S
L
A
S
E
A
P
S
Site 48
S704
P
A
G
K
S
L
A
S
E
A
P
S
Q
P
S
Site 49
S708
S
L
A
S
E
A
P
S
Q
P
S
L
N
G
G
Site 50
S711
S
E
A
P
S
Q
P
S
L
N
G
G
S
P
E
Site 51
S716
Q
P
S
L
N
G
G
S
P
E
G
V
E
S
Q
Site 52
S722
G
S
P
E
G
V
E
S
Q
D
G
V
D
H
F
Site 53
S749
M
Q
L
E
F
P
P
S
L
N
S
H
D
R
L
Site 54
S752
E
F
P
P
S
L
N
S
H
D
R
L
R
V
H
Site 55
S771
E
H
G
L
R
H
D
S
S
G
E
G
K
R
R
Site 56
S772
H
G
L
R
H
D
S
S
G
E
G
K
R
R
F
Site 57
T781
E
G
K
R
R
F
I
T
V
S
K
R
A
P
R
Site 58
S783
K
R
R
F
I
T
V
S
K
R
A
P
R
P
R
Site 59
T811
P
L
Q
P
V
P
P
T
P
A
Q
T
E
Q
P
Site 60
T832
P
D
Q
P
D
L
R
T
L
H
L
E
R
L
Q
Site 61
S843
E
R
L
Q
R
V
R
S
A
Q
G
Q
P
A
S
Site 62
S850
S
A
Q
G
Q
P
A
S
K
E
Q
Q
A
S
G
Site 63
S856
A
S
K
E
Q
Q
A
S
G
Q
Q
K
L
P
E
Site 64
T875
K
A
K
G
H
P
A
T
D
L
P
T
E
E
D
Site 65
T879
H
P
A
T
D
L
P
T
E
E
D
F
E
A
L
Site 66
S888
E
D
F
E
A
L
V
S
A
A
V
K
A
D
N
Site 67
Y920
C
Q
L
C
S
R
R
Y
C
L
S
H
H
L
P
Site 68
S945
A
H
A
R
Q
R
I
S
R
E
G
V
L
Y
A
Site 69
Y951
I
S
R
E
G
V
L
Y
A
G
S
G
T
K
N
Site 70
S954
E
G
V
L
Y
A
G
S
G
T
K
N
G
S
L
Site 71
T956
V
L
Y
A
G
S
G
T
K
N
G
S
L
D
P
Site 72
S960
G
S
G
T
K
N
G
S
L
D
P
A
K
R
A
Site 73
S978
R
R
L
D
K
K
L
S
E
L
S
N
Q
R
T
Site 74
S981
D
K
K
L
S
E
L
S
N
Q
R
T
S
R
R
Site 75
T985
S
E
L
S
N
Q
R
T
S
R
R
K
E
R
G
Site 76
S986
E
L
S
N
Q
R
T
S
R
R
K
E
R
G
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation