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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GluR5
Full Name:
Glutamate receptor, ionotropic kainate 1
Alias:
EAA3; Excitatory amino acid receptor 3; GluR-5; Glutamate receptor 5; GRIK1
Type:
Plasma membrane, Integral plasma membrane, Synapse, Postsynaptic membrane, Cell junction protein
Mass (Da):
103981
Number AA:
918
UniProt ID:
P39086
International Prot ID:
IPI00022850
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0005887
GO:0045211
Uniprot
OncoNet
Molecular Function:
GO:0005234
GO:0015277
PhosphoSite+
KinaseNET
Biological Process:
GO:0007417
GO:0007215
GO:0006811
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T45
R
I
G
G
I
F
E
T
V
E
N
E
P
V
N
Site 2
S64
A
F
K
F
A
V
T
S
I
N
R
N
R
T
L
Site 3
T70
T
S
I
N
R
N
R
T
L
M
P
N
T
T
L
Site 4
T78
L
M
P
N
T
T
L
T
Y
D
I
Q
R
I
N
Site 5
S89
Q
R
I
N
L
F
D
S
F
E
A
S
R
R
A
Site 6
S93
L
F
D
S
F
E
A
S
R
R
A
C
D
Q
L
Site 7
S114
L
F
G
P
S
H
S
S
S
V
S
A
V
Q
S
Site 8
S115
F
G
P
S
H
S
S
S
V
S
A
V
Q
S
I
Site 9
S117
P
S
H
S
S
S
V
S
A
V
Q
S
I
C
N
Site 10
S139
Q
T
R
W
K
H
P
S
V
D
N
K
D
L
F
Site 11
Y147
V
D
N
K
D
L
F
Y
I
N
L
Y
P
D
Y
Site 12
T172
V
L
Y
Y
N
W
K
T
V
T
V
V
Y
E
D
Site 13
S194
Q
E
L
I
K
A
P
S
R
Y
N
I
K
I
K
Site 14
Y226
M
K
K
G
K
E
F
Y
V
I
F
D
C
S
H
Site 15
Y272
L
D
L
E
L
Y
R
Y
S
G
V
N
M
T
G
Site 16
S273
D
L
E
L
Y
R
Y
S
G
V
N
M
T
G
F
Site 17
S298
S
S
I
I
E
K
W
S
M
E
R
L
Q
A
P
Site 18
T310
Q
A
P
P
R
P
E
T
G
L
L
D
G
M
M
Site 19
T342
S
H
R
A
S
Q
L
T
V
S
S
L
Q
C
H
Site 20
S345
A
S
Q
L
T
V
S
S
L
Q
C
H
R
H
K
Site 21
T373
E
A
R
W
D
G
L
T
G
H
I
T
F
N
K
Site 22
T377
D
G
L
T
G
H
I
T
F
N
K
T
N
G
L
Site 23
S394
D
F
D
L
D
I
I
S
L
K
E
E
G
T
E
Site 24
Y412
G
E
V
S
K
H
L
Y
K
V
W
K
K
I
G
Site 25
T430
S
N
S
G
L
N
M
T
D
S
N
K
D
K
S
Site 26
S432
S
G
L
N
M
T
D
S
N
K
D
K
S
S
N
Site 27
S437
T
D
S
N
K
D
K
S
S
N
I
T
D
S
L
Site 28
T441
K
D
K
S
S
N
I
T
D
S
L
A
N
R
T
Site 29
S443
K
S
S
N
I
T
D
S
L
A
N
R
T
L
I
Site 30
Y459
T
T
I
L
E
E
P
Y
V
M
Y
R
K
S
D
Site 31
S465
P
Y
V
M
Y
R
K
S
D
K
P
L
Y
G
N
Site 32
Y470
R
K
S
D
K
P
L
Y
G
N
D
R
F
E
G
Site 33
S487
L
D
L
L
K
E
L
S
N
I
L
G
F
I
Y
Site 34
Y494
S
N
I
L
G
F
I
Y
D
V
K
L
V
P
D
Site 35
Y504
K
L
V
P
D
G
K
Y
G
A
Q
N
D
K
G
Site 36
S545
R
E
K
V
I
D
F
S
K
P
F
M
T
L
G
Site 37
Y557
T
L
G
I
S
I
L
Y
R
K
P
N
G
T
N
Site 38
T563
L
Y
R
K
P
N
G
T
N
P
G
V
F
S
F
Site 39
Y602
V
I
A
R
F
T
P
Y
E
W
Y
N
P
H
P
Site 40
S681
L
T
V
E
R
M
E
S
P
I
D
S
A
D
D
Site 41
S685
R
M
E
S
P
I
D
S
A
D
D
L
A
K
Q
Site 42
Y697
A
K
Q
T
K
I
E
Y
G
A
V
R
D
G
S
Site 43
S704
Y
G
A
V
R
D
G
S
T
M
T
F
F
K
K
Site 44
T705
G
A
V
R
D
G
S
T
M
T
F
F
K
K
S
Site 45
T707
V
R
D
G
S
T
M
T
F
F
K
K
S
K
I
Site 46
S712
T
M
T
F
F
K
K
S
K
I
S
T
Y
E
K
Site 47
T716
F
K
K
S
K
I
S
T
Y
E
K
M
W
A
F
Site 48
T730
F
M
S
S
R
Q
Q
T
A
L
V
R
N
S
D
Site 49
S736
Q
T
A
L
V
R
N
S
D
E
G
I
Q
R
V
Site 50
Y748
Q
R
V
L
T
T
D
Y
A
L
L
M
E
S
T
Site 51
S756
A
L
L
M
E
S
T
S
I
E
Y
V
T
Q
R
Site 52
Y759
M
E
S
T
S
I
E
Y
V
T
Q
R
N
C
N
Site 53
T761
S
T
S
I
E
Y
V
T
Q
R
N
C
N
L
T
Site 54
T768
T
Q
R
N
C
N
L
T
Q
I
G
G
L
I
D
Site 55
S776
Q
I
G
G
L
I
D
S
K
G
Y
G
V
G
T
Site 56
T783
S
K
G
Y
G
V
G
T
P
I
G
S
P
Y
R
Site 57
S787
G
V
G
T
P
I
G
S
P
Y
R
D
K
I
T
Site 58
T794
S
P
Y
R
D
K
I
T
I
A
I
L
Q
L
Q
Site 59
Y859
V
A
I
G
E
F
I
Y
K
S
R
K
N
N
D
Site 60
T882
Y
G
L
Q
C
K
Q
T
H
P
T
N
S
T
S
Site 61
T885
Q
C
K
Q
T
H
P
T
N
S
T
S
G
T
T
Site 62
S887
K
Q
T
H
P
T
N
S
T
S
G
T
T
L
S
Site 63
S889
T
H
P
T
N
S
T
S
G
T
T
L
S
T
D
Site 64
T891
P
T
N
S
T
S
G
T
T
L
S
T
D
L
E
Site 65
S894
S
T
S
G
T
T
L
S
T
D
L
E
C
G
K
Site 66
T895
T
S
G
T
T
L
S
T
D
L
E
C
G
K
L
Site 67
S913
E
R
G
I
R
K
Q
S
S
V
H
T
V
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation