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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSMB10
Full Name:
Proteasome subunit beta type-10
Alias:
Beta2i; EC 3.4.25.1; LMP10; Macropain subunit MECl-1; MECL1; MGC1665; Multicatalytic endopeptidase complex subunit MECl-1; Proteasome (prosome, macropain) subunit, beta type, 10; Proteasome MECl-1; PSB10
Type:
Protease; Proteasome complex; EC 3.4.25.1
Mass (Da):
28936
Number AA:
273
UniProt ID:
P40306
International Prot ID:
IPI00027933
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0005839
Uniprot
OncoNet
Molecular Function:
GO:0004298
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0006959
GO:0051436
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
L
E
P
R
G
G
F
S
F
E
N
C
Q
R
N
Site 2
S22
E
N
C
Q
R
N
A
S
L
E
R
V
L
P
G
Site 3
T38
K
V
P
H
A
R
K
T
G
T
T
I
A
G
L
Site 4
T60
L
G
A
D
T
R
A
T
N
D
S
V
V
A
D
Site 5
S63
D
T
R
A
T
N
D
S
V
V
A
D
K
S
C
Site 6
S69
D
S
V
V
A
D
K
S
C
E
K
I
H
F
I
Site 7
Y81
H
F
I
A
P
K
I
Y
C
C
G
A
G
V
A
Site 8
S108
K
M
E
L
H
A
L
S
T
G
R
E
P
R
V
Site 9
T117
G
R
E
P
R
V
A
T
V
T
R
I
L
R
Q
Site 10
T119
E
P
R
V
A
T
V
T
R
I
L
R
Q
T
L
Site 11
T125
V
T
R
I
L
R
Q
T
L
F
R
Y
Q
G
H
Site 12
Y129
L
R
Q
T
L
F
R
Y
Q
G
H
V
G
A
S
Site 13
Y150
D
L
T
G
P
Q
L
Y
G
V
H
P
H
G
S
Site 14
S157
Y
G
V
H
P
H
G
S
Y
S
R
L
P
F
T
Site 15
Y158
G
V
H
P
H
G
S
Y
S
R
L
P
F
T
A
Site 16
S159
V
H
P
H
G
S
Y
S
R
L
P
F
T
A
L
Site 17
T164
S
Y
S
R
L
P
F
T
A
L
G
S
G
Q
D
Site 18
T227
T
G
A
K
L
L
R
T
L
S
S
P
T
E
P
Site 19
S229
A
K
L
L
R
T
L
S
S
P
T
E
P
V
K
Site 20
S230
K
L
L
R
T
L
S
S
P
T
E
P
V
K
R
Site 21
S238
P
T
E
P
V
K
R
S
G
R
Y
H
F
V
P
Site 22
T247
R
Y
H
F
V
P
G
T
T
A
V
L
T
Q
T
Site 23
T259
T
Q
T
V
K
P
L
T
L
E
L
V
E
E
T
Site 24
T266
T
L
E
L
V
E
E
T
V
Q
A
M
E
V
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation