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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PBX1
Full Name:
Pre-B-cell leukemia transcription factor 1
Alias:
Homeobox protein PBX1
Type:
Mass (Da):
46608
Number AA:
430
UniProt ID:
P40424
International Prot ID:
IPI00028415
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005730
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0003006
GO:0006139
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
E
Q
P
R
L
M
H
S
H
A
G
V
G
M
A
Site 2
S23
M
A
G
H
P
G
L
S
Q
H
L
Q
D
G
A
Site 3
T52
D
I
L
Q
Q
I
M
T
I
T
D
Q
S
L
D
Site 4
S57
I
M
T
I
T
D
Q
S
L
D
E
A
Q
A
R
Site 5
S91
I
K
E
K
T
V
L
S
I
R
G
A
Q
E
E
Site 6
T101
G
A
Q
E
E
E
P
T
D
P
Q
L
M
R
L
Site 7
S141
A
A
S
G
G
A
G
S
D
N
S
V
E
H
S
Site 8
S144
G
G
A
G
S
D
N
S
V
E
H
S
D
Y
R
Site 9
S148
S
D
N
S
V
E
H
S
D
Y
R
A
K
L
S
Site 10
Y150
N
S
V
E
H
S
D
Y
R
A
K
L
S
Q
I
Site 11
S155
S
D
Y
R
A
K
L
S
Q
I
R
Q
I
Y
H
Site 12
Y161
L
S
Q
I
R
Q
I
Y
H
T
E
L
E
K
Y
Site 13
T163
Q
I
R
Q
I
Y
H
T
E
L
E
K
Y
E
Q
Site 14
Y168
Y
H
T
E
L
E
K
Y
E
Q
A
C
N
E
F
Site 15
S187
M
N
L
L
R
E
Q
S
R
T
R
P
I
S
P
Site 16
T189
L
L
R
E
Q
S
R
T
R
P
I
S
P
K
E
Site 17
S193
Q
S
R
T
R
P
I
S
P
K
E
I
E
R
M
Site 18
S202
K
E
I
E
R
M
V
S
I
I
H
R
K
F
S
Site 19
S209
S
I
I
H
R
K
F
S
S
I
Q
M
Q
L
K
Site 20
S210
I
I
H
R
K
F
S
S
I
Q
M
Q
L
K
Q
Site 21
Y251
A
T
E
I
L
N
E
Y
F
Y
S
H
L
S
N
Site 22
Y253
E
I
L
N
E
Y
F
Y
S
H
L
S
N
P
Y
Site 23
S257
E
Y
F
Y
S
H
L
S
N
P
Y
P
S
E
E
Site 24
Y260
Y
S
H
L
S
N
P
Y
P
S
E
E
A
K
E
Site 25
Y291
F
G
N
K
R
I
R
Y
K
K
N
I
G
K
F
Site 26
Y305
F
Q
E
E
A
N
I
Y
A
A
K
T
A
V
T
Site 27
S317
A
V
T
A
T
N
V
S
A
H
G
S
Q
A
N
Site 28
S321
T
N
V
S
A
H
G
S
Q
A
N
S
P
S
T
Site 29
S325
A
H
G
S
Q
A
N
S
P
S
T
P
N
S
A
Site 30
S327
G
S
Q
A
N
S
P
S
T
P
N
S
A
G
S
Site 31
T328
S
Q
A
N
S
P
S
T
P
N
S
A
G
S
S
Site 32
S331
N
S
P
S
T
P
N
S
A
G
S
S
S
S
F
Site 33
S334
S
T
P
N
S
A
G
S
S
S
S
F
N
M
S
Site 34
S335
T
P
N
S
A
G
S
S
S
S
F
N
M
S
N
Site 35
S336
P
N
S
A
G
S
S
S
S
F
N
M
S
N
S
Site 36
S337
N
S
A
G
S
S
S
S
F
N
M
S
N
S
G
Site 37
S341
S
S
S
S
F
N
M
S
N
S
G
D
L
F
M
Site 38
S343
S
S
F
N
M
S
N
S
G
D
L
F
M
S
V
Site 39
S349
N
S
G
D
L
F
M
S
V
Q
S
L
N
G
D
Site 40
S352
D
L
F
M
S
V
Q
S
L
N
G
D
S
Y
Q
Site 41
S357
V
Q
S
L
N
G
D
S
Y
Q
G
A
Q
V
G
Site 42
Y358
Q
S
L
N
G
D
S
Y
Q
G
A
Q
V
G
A
Site 43
S369
Q
V
G
A
N
V
Q
S
Q
V
D
T
L
R
H
Site 44
T373
N
V
Q
S
Q
V
D
T
L
R
H
V
I
S
Q
Site 45
S379
D
T
L
R
H
V
I
S
Q
T
G
G
Y
S
D
Site 46
T381
L
R
H
V
I
S
Q
T
G
G
Y
S
D
G
L
Site 47
S391
Y
S
D
G
L
A
A
S
Q
M
Y
S
P
Q
G
Site 48
S395
L
A
A
S
Q
M
Y
S
P
Q
G
I
S
A
N
Site 49
T409
N
G
G
W
Q
D
A
T
T
P
S
S
V
T
S
Site 50
T410
G
G
W
Q
D
A
T
T
P
S
S
V
T
S
P
Site 51
S412
W
Q
D
A
T
T
P
S
S
V
T
S
P
T
E
Site 52
S413
Q
D
A
T
T
P
S
S
V
T
S
P
T
E
G
Site 53
S416
T
T
P
S
S
V
T
S
P
T
E
G
P
G
S
Site 54
T418
P
S
S
V
T
S
P
T
E
G
P
G
S
V
H
Site 55
S423
S
P
T
E
G
P
G
S
V
H
S
D
T
S
N
Site 56
S426
E
G
P
G
S
V
H
S
D
T
S
N
_
_
_
Site 57
S429
G
S
V
H
S
D
T
S
N
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation