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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RFC3
Full Name:
Replication factor C subunit 3
Alias:
A1 38 kDa subunit; MGC5276; Replication factor C (activator 1) 3; Replication factor C 38 kDa; RFC, 38 kD subunit; RFC38
Type:
DNA replication protein
Mass (Da):
40556
Number AA:
356
UniProt ID:
P40938
International Prot ID:
IPI00031521
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005663
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0003689
GO:0000166
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006271
GO:0000731
GO:0006297
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
S
L
W
V
D
K
Y
R
P
C
S
L
G
R
Site 2
S12
V
D
K
Y
R
P
C
S
L
G
R
L
D
Y
H
Site 3
Y18
C
S
L
G
R
L
D
Y
H
K
E
Q
A
A
Q
Site 4
Y41
D
F
P
H
L
L
V
Y
G
P
S
G
A
G
K
Site 5
S44
H
L
L
V
Y
G
P
S
G
A
G
K
K
T
R
Site 6
Y60
M
C
I
L
R
E
L
Y
G
V
G
V
E
K
L
Site 7
T73
K
L
R
I
E
H
Q
T
I
T
T
P
S
K
K
Site 8
T76
I
E
H
Q
T
I
T
T
P
S
K
K
K
I
E
Site 9
S85
S
K
K
K
I
E
I
S
T
I
A
S
N
Y
H
Site 10
Y91
I
S
T
I
A
S
N
Y
H
L
E
V
N
P
S
Site 11
S98
Y
H
L
E
V
N
P
S
D
A
G
N
S
D
R
Site 12
T114
V
I
Q
E
M
L
K
T
V
A
Q
S
Q
Q
L
Site 13
T123
A
Q
S
Q
Q
L
E
T
N
S
Q
R
D
F
K
Site 14
S125
S
Q
Q
L
E
T
N
S
Q
R
D
F
K
V
V
Site 15
T151
A
Q
H
A
L
R
R
T
M
E
K
Y
M
S
T
Site 16
Y155
L
R
R
T
M
E
K
Y
M
S
T
C
R
L
I
Site 17
S209
K
E
G
L
N
L
P
S
Q
L
A
H
R
L
A
Site 18
S219
A
H
R
L
A
E
K
S
C
R
N
L
R
K
A
Site 19
Y238
E
A
C
R
V
Q
Q
Y
P
F
T
A
D
Q
E
Site 20
T249
A
D
Q
E
I
P
E
T
D
W
E
V
Y
L
R
Site 21
Y254
P
E
T
D
W
E
V
Y
L
R
E
T
A
N
A
Site 22
T258
W
E
V
Y
L
R
E
T
A
N
A
I
V
S
Q
Site 23
T267
N
A
I
V
S
Q
Q
T
P
Q
R
L
L
E
V
Site 24
Y317
E
V
A
Q
M
A
A
Y
Y
E
H
R
L
Q
L
Site 25
Y318
V
A
Q
M
A
A
Y
Y
E
H
R
L
Q
L
G
Site 26
S326
E
H
R
L
Q
L
G
S
K
A
I
Y
H
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation