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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCNF
Full Name:
Cyclin-F
Alias:
F-box only protein 1
Type:
Mass (Da):
87640
Number AA:
786
UniProt ID:
P41002
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T31
R
R
R
P
R
N
L
T
I
L
S
L
P
E
D
Site 2
S77
A
S
V
W
A
C
A
S
F
Q
E
L
W
P
S
Site 3
S84
S
F
Q
E
L
W
P
S
P
G
N
L
K
L
F
Site 4
S117
Y
L
Y
N
E
G
L
S
V
S
D
E
A
R
A
Site 5
S119
Y
N
E
G
L
S
V
S
D
E
A
R
A
E
V
Site 6
S132
E
V
N
G
L
K
A
S
R
F
F
S
L
A
E
Site 7
S185
L
Q
R
T
H
K
A
S
I
L
H
C
L
G
R
Site 8
S195
H
C
L
G
R
V
L
S
L
F
E
D
E
E
K
Site 9
S221
A
H
Q
G
C
L
T
S
S
Y
L
L
W
E
S
Site 10
S222
H
Q
G
C
L
T
S
S
Y
L
L
W
E
S
D
Site 11
Y223
Q
G
C
L
T
S
S
Y
L
L
W
E
S
D
R
Site 12
S228
S
S
Y
L
L
W
E
S
D
R
R
T
D
V
S
Site 13
T232
L
W
E
S
D
R
R
T
D
V
S
D
P
G
R
Site 14
S235
S
D
R
R
T
D
V
S
D
P
G
R
C
L
H
Site 15
S243
D
P
G
R
C
L
H
S
F
R
K
L
R
D
Y
Site 16
Y250
S
F
R
K
L
R
D
Y
A
A
K
G
C
W
E
Site 17
S290
V
C
Q
L
F
Q
A
S
Q
A
V
S
K
Q
Q
Site 18
S294
F
Q
A
S
Q
A
V
S
K
Q
Q
V
F
S
V
Site 19
T308
V
Q
K
G
L
N
D
T
M
R
Y
I
L
I
D
Site 20
Y341
T
V
E
C
V
D
R
Y
L
R
R
R
L
V
P
Site 21
Y350
R
R
R
L
V
P
R
Y
R
L
Q
L
L
G
I
Site 22
Y385
V
W
L
T
D
N
T
Y
K
Y
E
D
L
V
R
Site 23
Y387
L
T
D
N
T
Y
K
Y
E
D
L
V
R
M
M
Site 24
S399
R
M
M
G
E
I
V
S
A
L
E
G
K
I
R
Site 25
T409
E
G
K
I
R
V
P
T
V
V
D
Y
K
E
V
Site 26
T463
A
L
L
L
A
R
L
T
H
G
Q
T
Q
P
W
Site 27
T478
T
T
Q
L
W
D
L
T
G
F
S
Y
E
D
L
Site 28
Y505
H
D
D
A
P
K
D
Y
R
Q
V
S
L
T
A
Site 29
S509
P
K
D
Y
R
Q
V
S
L
T
A
V
K
Q
R
Site 30
T511
D
Y
R
Q
V
S
L
T
A
V
K
Q
R
F
E
Site 31
Y522
Q
R
F
E
D
K
R
Y
G
E
I
S
Q
E
E
Site 32
S526
D
K
R
Y
G
E
I
S
Q
E
E
V
L
S
Y
Site 33
S546
A
L
G
V
T
Q
D
S
P
D
P
P
T
F
L
Site 34
T551
Q
D
S
P
D
P
P
T
F
L
S
T
G
E
I
Site 35
S554
P
D
P
P
T
F
L
S
T
G
E
I
H
A
F
Site 36
S563
G
E
I
H
A
F
L
S
S
P
S
G
R
R
T
Site 37
S564
E
I
H
A
F
L
S
S
P
S
G
R
R
T
K
Site 38
S566
H
A
F
L
S
S
P
S
G
R
R
T
K
R
K
Site 39
T570
S
S
P
S
G
R
R
T
K
R
K
R
E
N
S
Site 40
S577
T
K
R
K
R
E
N
S
L
Q
E
D
R
G
S
Site 41
S584
S
L
Q
E
D
R
G
S
F
V
T
T
P
T
A
Site 42
T587
E
D
R
G
S
F
V
T
T
P
T
A
E
L
S
Site 43
T588
D
R
G
S
F
V
T
T
P
T
A
E
L
S
S
Site 44
T590
G
S
F
V
T
T
P
T
A
E
L
S
S
Q
E
Site 45
S594
T
T
P
T
A
E
L
S
S
Q
E
E
T
L
L
Site 46
S595
T
P
T
A
E
L
S
S
Q
E
E
T
L
L
G
Site 47
T599
E
L
S
S
Q
E
E
T
L
L
G
S
F
L
D
Site 48
S603
Q
E
E
T
L
L
G
S
F
L
D
W
S
L
D
Site 49
Y615
S
L
D
C
C
S
G
Y
E
G
D
Q
E
S
E
Site 50
S621
G
Y
E
G
D
Q
E
S
E
G
E
K
E
G
D
Site 51
T630
G
E
K
E
G
D
V
T
A
P
S
G
I
L
D
Site 52
T675
P
Q
A
L
A
L
D
T
Q
I
P
A
T
P
G
Site 53
T680
L
D
T
Q
I
P
A
T
P
G
P
K
P
L
V
Site 54
S690
P
K
P
L
V
R
T
S
R
E
P
G
K
D
V
Site 55
T698
R
E
P
G
K
D
V
T
T
S
G
Y
S
S
V
Site 56
T699
E
P
G
K
D
V
T
T
S
G
Y
S
S
V
S
Site 57
S700
P
G
K
D
V
T
T
S
G
Y
S
S
V
S
T
Site 58
Y702
K
D
V
T
T
S
G
Y
S
S
V
S
T
A
S
Site 59
S704
V
T
T
S
G
Y
S
S
V
S
T
A
S
P
T
Site 60
S706
T
S
G
Y
S
S
V
S
T
A
S
P
T
S
S
Site 61
T707
S
G
Y
S
S
V
S
T
A
S
P
T
S
S
V
Site 62
S709
Y
S
S
V
S
T
A
S
P
T
S
S
V
D
G
Site 63
S712
V
S
T
A
S
P
T
S
S
V
D
G
G
L
G
Site 64
S713
S
T
A
S
P
T
S
S
V
D
G
G
L
G
A
Site 65
S726
G
A
L
P
Q
P
T
S
V
L
S
L
D
S
D
Site 66
S729
P
Q
P
T
S
V
L
S
L
D
S
D
S
H
T
Site 67
S732
T
S
V
L
S
L
D
S
D
S
H
T
Q
P
C
Site 68
S734
V
L
S
L
D
S
D
S
H
T
Q
P
C
H
H
Site 69
T736
S
L
D
S
D
S
H
T
Q
P
C
H
H
Q
A
Site 70
S754
C
L
Q
C
R
P
P
S
P
P
E
S
S
V
P
Site 71
S758
R
P
P
S
P
P
E
S
S
V
P
Q
Q
Q
V
Site 72
S759
P
P
S
P
P
E
S
S
V
P
Q
Q
Q
V
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation