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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LGTN
Full Name:
Ligatin
Alias:
Hepatocellular carcinoma-associated antigen 56
Type:
Mass (Da):
64706
Number AA:
584
UniProt ID:
P41214
International Prot ID:
IPI00013160
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0019898
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0005515
GO:0004872
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
GO:0006413
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
K
A
F
R
V
K
S
N
T
A
I
K
G
S
Site 2
T12
A
F
R
V
K
S
N
T
A
I
K
G
S
D
R
Site 3
S17
S
N
T
A
I
K
G
S
D
R
R
K
L
R
A
Site 4
T27
R
K
L
R
A
D
V
T
T
A
F
P
T
L
G
Site 5
T62
A
H
K
G
D
A
V
T
V
Y
V
S
G
G
N
Site 6
Y80
F
E
L
E
K
N
L
Y
P
T
V
Y
T
L
W
Site 7
T82
L
E
K
N
L
Y
P
T
V
Y
T
L
W
S
Y
Site 8
Y84
K
N
L
Y
P
T
V
Y
T
L
W
S
Y
P
D
Site 9
T85
N
L
Y
P
T
V
Y
T
L
W
S
Y
P
D
L
Site 10
S88
P
T
V
Y
T
L
W
S
Y
P
D
L
L
P
T
Site 11
S159
S
T
A
E
M
L
T
S
G
L
K
G
R
G
F
Site 12
S167
G
L
K
G
R
G
F
S
V
L
H
T
Y
Q
D
Site 13
T171
R
G
F
S
V
L
H
T
Y
Q
D
H
L
W
R
Site 14
Y172
G
F
S
V
L
H
T
Y
Q
D
H
L
W
R
S
Site 15
S179
Y
Q
D
H
L
W
R
S
G
N
K
S
S
P
P
Site 16
S183
L
W
R
S
G
N
K
S
S
P
P
S
I
A
P
Site 17
S184
W
R
S
G
N
K
S
S
P
P
S
I
A
P
L
Site 18
S187
G
N
K
S
S
P
P
S
I
A
P
L
A
L
D
Site 19
S195
I
A
P
L
A
L
D
S
A
D
L
S
E
E
K
Site 20
S199
A
L
D
S
A
D
L
S
E
E
K
G
S
V
Q
Site 21
S204
D
L
S
E
E
K
G
S
V
Q
M
D
S
T
L
Site 22
S209
K
G
S
V
Q
M
D
S
T
L
Q
G
D
M
R
Site 23
T210
G
S
V
Q
M
D
S
T
L
Q
G
D
M
R
H
Site 24
T219
Q
G
D
M
R
H
M
T
L
E
G
E
E
E
N
Site 25
S237
H
Q
A
R
E
D
K
S
L
S
E
A
P
E
D
Site 26
S239
A
R
E
D
K
S
L
S
E
A
P
E
D
T
S
Site 27
S246
S
E
A
P
E
D
T
S
T
R
G
L
N
Q
D
Site 28
T247
E
A
P
E
D
T
S
T
R
G
L
N
Q
D
S
Site 29
S254
T
R
G
L
N
Q
D
S
T
D
S
K
T
L
Q
Site 30
T255
R
G
L
N
Q
D
S
T
D
S
K
T
L
Q
E
Site 31
S257
L
N
Q
D
S
T
D
S
K
T
L
Q
E
Q
M
Site 32
S312
R
Q
L
D
I
K
K
S
S
Y
K
K
L
S
K
Site 33
Y314
L
D
I
K
K
S
S
Y
K
K
L
S
K
F
L
Site 34
S318
K
S
S
Y
K
K
L
S
K
F
L
Q
Q
M
Q
Site 35
T353
D
W
K
H
P
R
I
T
S
F
V
I
P
E
P
Site 36
S354
W
K
H
P
R
I
T
S
F
V
I
P
E
P
S
Site 37
S361
S
F
V
I
P
E
P
S
P
T
S
Q
T
I
Q
Site 38
T363
V
I
P
E
P
S
P
T
S
Q
T
I
Q
E
G
Site 39
S364
I
P
E
P
S
P
T
S
Q
T
I
Q
E
G
S
Site 40
Y376
E
G
S
R
E
Q
P
Y
H
P
P
D
I
K
P
Site 41
S398
M
T
L
L
F
Q
E
S
G
H
K
K
G
S
F
Site 42
S404
E
S
G
H
K
K
G
S
F
L
E
G
S
E
V
Site 43
T413
L
E
G
S
E
V
R
T
I
V
I
N
Y
A
K
Site 44
S459
V
M
K
L
P
W
D
S
L
L
T
R
C
L
E
Site 45
Y472
L
E
K
L
Q
P
A
Y
Q
V
T
L
P
G
Q
Site 46
T494
R
I
C
P
I
D
I
T
L
A
Q
R
A
S
N
Site 47
T505
R
A
S
N
K
K
V
T
V
V
R
N
L
E
A
Site 48
S531
L
Q
Q
R
C
Q
A
S
T
T
V
N
P
A
P
Site 49
T532
Q
Q
R
C
Q
A
S
T
T
V
N
P
A
P
G
Site 50
T533
Q
R
C
Q
A
S
T
T
V
N
P
A
P
G
A
Site 51
S543
P
A
P
G
A
K
D
S
L
Q
V
Q
I
Q
G
Site 52
Y564
G
W
L
L
L
E
E
Y
Q
L
P
R
K
H
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation