KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
WNT5A
Full Name:
Protein Wnt-5a
Alias:
Type:
Mass (Da):
42339
Number AA:
380
UniProt ID:
P41221
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S76
C
S
Q
L
A
G
L
S
Q
G
Q
K
K
L
C
Site 2
Y86
Q
K
K
L
C
H
L
Y
Q
D
H
M
Q
Y
I
Site 3
T99
Y
I
G
E
G
A
K
T
G
I
K
E
C
Q
Y
Site 4
Y106
T
G
I
K
E
C
Q
Y
Q
F
R
H
R
R
W
Site 5
S116
R
H
R
R
W
N
C
S
T
V
D
N
T
S
V
Site 6
T117
H
R
R
W
N
C
S
T
V
D
N
T
S
V
F
Site 7
T121
N
C
S
T
V
D
N
T
S
V
F
G
R
V
M
Site 8
S122
C
S
T
V
D
N
T
S
V
F
G
R
V
M
Q
Site 9
T135
M
Q
I
G
S
R
E
T
A
F
T
Y
A
V
S
Site 10
T138
G
S
R
E
T
A
F
T
Y
A
V
S
A
A
G
Site 11
S151
A
G
V
V
N
A
M
S
R
A
C
R
E
G
E
Site 12
S160
A
C
R
E
G
E
L
S
T
C
G
C
S
R
A
Site 13
Y188
G
C
G
D
N
I
D
Y
G
Y
R
F
A
K
E
Site 14
Y190
G
D
N
I
D
Y
G
Y
R
F
A
K
E
F
V
Site 15
S210
E
R
I
H
A
K
G
S
Y
E
S
A
R
I
L
Site 16
Y211
R
I
H
A
K
G
S
Y
E
S
A
R
I
L
M
Site 17
S213
H
A
K
G
S
Y
E
S
A
R
I
L
M
N
L
Site 18
T229
N
N
E
A
G
R
R
T
V
Y
N
L
A
D
V
Site 19
Y231
E
A
G
R
R
T
V
Y
N
L
A
D
V
A
C
Site 20
S244
A
C
K
C
H
G
V
S
G
S
C
S
L
K
T
Site 21
S248
H
G
V
S
G
S
C
S
L
K
T
C
W
L
Q
Site 22
T251
S
G
S
C
S
L
K
T
C
W
L
Q
L
A
D
Site 23
Y270
G
D
A
L
K
E
K
Y
D
S
A
A
A
M
R
Site 24
S272
A
L
K
E
K
Y
D
S
A
A
A
M
R
L
N
Site 25
S289
G
K
L
V
Q
V
N
S
R
F
N
S
P
T
T
Site 26
S293
Q
V
N
S
R
F
N
S
P
T
T
Q
D
L
V
Site 27
T295
N
S
R
F
N
S
P
T
T
Q
D
L
V
Y
I
Site 28
T296
S
R
F
N
S
P
T
T
Q
D
L
V
Y
I
D
Site 29
Y301
P
T
T
Q
D
L
V
Y
I
D
P
S
P
D
Y
Site 30
S305
D
L
V
Y
I
D
P
S
P
D
Y
C
V
R
N
Site 31
Y308
Y
I
D
P
S
P
D
Y
C
V
R
N
E
S
T
Site 32
S314
D
Y
C
V
R
N
E
S
T
G
S
L
G
T
Q
Site 33
S317
V
R
N
E
S
T
G
S
L
G
T
Q
G
R
L
Site 34
T328
Q
G
R
L
C
N
K
T
S
E
G
M
D
G
C
Site 35
S329
G
R
L
C
N
K
T
S
E
G
M
D
G
C
E
Site 36
Y344
L
M
C
C
G
R
G
Y
D
Q
F
K
T
V
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation