PhosphoNET

           
Protein Info 
   
Short Name:  SOX3
Full Name:  Transcription factor SOX-3
Alias:  ghdx; mrgh; otthump00000024166; php; phpx; sox3; soxb; sry (sex determining region y)-box 3; transcription factor sox-3
Type:  Transcription factor; DNA binding protein
Mass (Da):  45210
Number AA:  446
UniProt ID:  P41225
International Prot ID:  IPI00240510
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0003677     PhosphoSite+ KinaseNET
Biological Process:  GO:0045449  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MRPVRENSSGARSPR
Site 2S9RPVRENSSGARSPRV
Site 3S13ENSSGARSPRVPADL
Site 4S34SLPFPPDSLAHRPPS
Site 5S41SLAHRPPSSAPTESQ
Site 6S42LAHRPPSSAPTESQG
Site 7T45RPPSSAPTESQGLFT
Site 8S47PSSAPTESQGLFTVA
Site 9S62APAPGAPSPPATLAH
Site 10T82AMYSLLETELKNPVG
Site 11T90ELKNPVGTPTQAAGT
Site 12S109APGGAGKSSANAAGG
Site 13S110PGGAGKSSANAAGGA
Site 14S119NAAGGANSGGGSSGG
Site 15S123GANSGGGSSGGASGG
Site 16S124ANSGGGSSGGASGGG
Site 17S128GGSSGGASGGGGGTD
Site 18S167ENPKMHNSEISKRLG
Site 19S170KMHNSEISKRLGADW
Site 20T181GADWKLLTDAEKRPF
Site 21Y203RAVHMKEYPDYKYRP
Site 22Y206HMKEYPDYKYRPRRK
Site 23Y208KEYPDYKYRPRRKTK
Site 24T214KYRPRRKTKTLLKKD
Site 25T216RPRRKTKTLLKKDKY
Site 26Y223TLLKKDKYSLPSGLL
Site 27S224LLKKDKYSLPSGLLP
Site 28T260GVGQRLDTYTHVNGW
Site 29Y261VGQRLDTYTHVNGWA
Site 30Y272NGWANGAYSLVQEQL
Site 31S273GWANGAYSLVQEQLG
Site 32Y281LVQEQLGYAQPPSMS
Site 33S286LGYAQPPSMSSPPPP
Site 34S288YAQPPSMSSPPPPPA
Site 35S289AQPPSMSSPPPPPAL
Site 36Y302ALPPMHRYDMAGLQY
Site 37S310DMAGLQYSPMMPPGA
Site 38S372MSLGPMGSVVKSEPS
Site 39S376PMGSVVKSEPSSPPP
Site 40S379SVVKSEPSSPPPAIA
Site 41S380VVKSEPSSPPPAIAS
Site 42S387SPPPAIASHSQRACL
Site 43S389PPAIASHSQRACLGD
Site 44S402GDLRDMISMYLPPGG
Site 45Y404LRDMISMYLPPGGDA
Site 46S416GDAADAASPLPGGRL
Site 47Y430LHGVHQHYQGAGTAV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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