PhosphoNET

           
Protein Info 
   
Short Name:  HNF4A
Full Name:  Hepatocyte nuclear factor 4-alpha
Alias:  HNF4; HNF-4-alpha; NR2A1; TCF14; Transcription factor 14
Type:  Transcription protein
Mass (Da):  52785
Number AA:  465
UniProt ID:  P41235
International Prot ID:  IPI00216080
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0005504  GO:0010843  GO:0042803 PhosphoSite+ KinaseNET
Biological Process:  GO:0007596  GO:0055088  GO:0030308 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y15VDMDMADYSAALDPA
Site 2S16DMDMADYSAALDPAY
Site 3Y23SAALDPAYTTLEFEN
Site 4S41LTMGNDTSPSEGTNL
Site 5S43MGNDTSPSEGTNLNA
Site 6T68AICGDRATGKHYGAS
Site 7Y72DRATGKHYGASSCDG
Site 8S75TGKHYGASSCDGCKG
Site 9S76GKHYGASSCDGCKGF
Site 10S87CKGFFRRSVRKNHMY
Site 11Y94SVRKNHMYSCRFSRQ
Site 12Y114DKRNQCRYCRLKKCF
Site 13S138QNERDRISTRRSSYE
Site 14T139NERDRISTRRSSYED
Site 15S142DRISTRRSSYEDSSL
Site 16S143RISTRRSSYEDSSLP
Site 17Y144ISTRRSSYEDSSLPS
Site 18S147RRSSYEDSSLPSINA
Site 19S148RSSYEDSSLPSINAL
Site 20S151YEDSSLPSINALLQA
Site 21T166EVLSRQITSPVSGIN
Site 22S167VLSRQITSPVSGING
Site 23S170RQITSPVSGINGDIR
Site 24S190SIADVCESMKEQLLV
Site 25T233EHLLLGATKRSMVFK
Site 26Y286LQIDDNEYAYLKAII
Site 27Y288IDDNEYAYLKAIIFF
Site 28S303DPDAKGLSDPGKIKR
Site 29S313GKIKRLRSQVQVSLE
Site 30S318LRSQVQVSLEDYIND
Site 31Y322VQVSLEDYINDRQYD
Site 32Y328DYINDRQYDSRGRFG
Site 33S330INDRQYDSRGRFGEL
Site 34S378QEMLLGGSPSDAPHA
Site 35S380MLLGGSPSDAPHAHH
Site 36T429RPRGQAATPETPQPS
Site 37T432GQAATPETPQPSPPG
Site 38S436TPETPQPSPPGGSGS
Site 39S443SPPGGSGSEPYKLLP
Site 40Y446GGSGSEPYKLLPGAV
Site 41T455LLPGAVATIVKPLSA
Site 42T469AIPQPTITKQEVI__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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