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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPP1R2
Full Name:
Protein phosphatase inhibitor 2
Alias:
I-2; Inhibitor 2; IPP2; IPP-2; Protein phosphatase 1, regulatory (inhibitor) subunit 2
Type:
Inhibitor protein; Protein phosphatase, regulatory subunit
Mass (Da):
23015
Number AA:
205
UniProt ID:
P41236
International Prot ID:
IPI00220402
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004865
PhosphoSite+
KinaseNET
Biological Process:
GO:0005977
GO:0043666
GO:0009966
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
A
S
T
A
S
H
R
P
I
K
G
I
Site 2
T19
K
G
I
L
K
N
K
T
S
T
T
S
S
M
V
Site 3
S20
G
I
L
K
N
K
T
S
T
T
S
S
M
V
A
Site 4
S23
K
N
K
T
S
T
T
S
S
M
V
A
S
A
E
Site 5
S24
N
K
T
S
T
T
S
S
M
V
A
S
A
E
Q
Site 6
S28
T
T
S
S
M
V
A
S
A
E
Q
P
R
G
N
Site 7
S41
G
N
V
D
E
E
L
S
K
K
S
Q
K
W
D
Site 8
S44
D
E
E
L
S
K
K
S
Q
K
W
D
E
M
N
Site 9
T55
D
E
M
N
I
L
A
T
Y
H
P
A
D
K
D
Site 10
Y56
E
M
N
I
L
A
T
Y
H
P
A
D
K
D
Y
Site 11
Y63
Y
H
P
A
D
K
D
Y
G
L
M
K
I
D
E
Site 12
S72
L
M
K
I
D
E
P
S
T
P
Y
H
S
M
M
Site 13
T73
M
K
I
D
E
P
S
T
P
Y
H
S
M
M
G
Site 14
Y75
I
D
E
P
S
T
P
Y
H
S
M
M
G
D
D
Site 15
S77
E
P
S
T
P
Y
H
S
M
M
G
D
D
E
D
Site 16
S87
G
D
D
E
D
A
C
S
D
T
E
A
T
E
A
Site 17
T89
D
E
D
A
C
S
D
T
E
A
T
E
A
M
A
Site 18
T92
A
C
S
D
T
E
A
T
E
A
M
A
P
D
I
Site 19
Y114
A
E
G
L
E
P
K
Y
R
I
Q
E
Q
E
S
Site 20
S121
Y
R
I
Q
E
Q
E
S
S
G
E
E
D
S
D
Site 21
S122
R
I
Q
E
Q
E
S
S
G
E
E
D
S
D
L
Site 22
S127
E
S
S
G
E
E
D
S
D
L
S
P
E
E
R
Site 23
S130
G
E
E
D
S
D
L
S
P
E
E
R
E
K
K
Site 24
Y148
E
M
K
R
K
L
H
Y
N
E
G
L
N
I
K
Site 25
T177
E
D
E
E
M
L
E
T
A
D
G
E
S
M
N
Site 26
T185
A
D
G
E
S
M
N
T
E
E
S
N
Q
G
S
Site 27
S188
E
S
M
N
T
E
E
S
N
Q
G
S
T
P
S
Site 28
S192
T
E
E
S
N
Q
G
S
T
P
S
D
Q
Q
Q
Site 29
T193
E
E
S
N
Q
G
S
T
P
S
D
Q
Q
Q
N
Site 30
S195
S
N
Q
G
S
T
P
S
D
Q
Q
Q
N
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation