KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
GluR2
Full Name:
Glutamate receptor 2
Alias:
GluR-2; GluR-B; GluR-K2; Glutamate receptor ionotropic, AMPA 2; GRIA2
Type:
Channel protein; Ion channel, ligand-gated, calcium
Mass (Da):
98821
Number AA:
883
UniProt ID:
P42262
International Prot ID:
IPI00030882
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0030666
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004971
GO:0005234
GO:0015277
PhosphoSite+
KinaseNET
Biological Process:
GO:0006811
GO:0007165
GO:0007268
Phosida
TranscriptoNet
STRING
Kinexus Products
Glutamate receptor 2 (K844-S858, human) A849-Q853 deleted peptide - Powder PE-01ABL90#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01ABL90
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y41
P
R
G
A
D
Q
E
Y
S
A
F
R
V
G
M
Site 2
S42
R
G
A
D
Q
E
Y
S
A
F
R
V
G
M
V
Site 3
S54
G
M
V
Q
F
S
T
S
E
F
R
L
T
P
H
Site 4
T59
S
T
S
E
F
R
L
T
P
H
I
D
N
L
E
Site 5
Y92
V
Y
A
I
F
G
F
Y
D
K
K
S
V
N
T
Site 6
S115
H
V
S
F
I
T
P
S
F
P
T
D
G
T
H
Site 7
T121
P
S
F
P
T
D
G
T
H
P
F
V
I
Q
M
Site 8
Y143
L
L
S
L
I
E
Y
Y
Q
W
D
K
F
A
Y
Site 9
Y150
Y
Q
W
D
K
F
A
Y
L
Y
D
S
D
R
G
Site 10
Y152
W
D
K
F
A
Y
L
Y
D
S
D
R
G
L
S
Site 11
S154
K
F
A
Y
L
Y
D
S
D
R
G
L
S
T
L
Site 12
S159
Y
D
S
D
R
G
L
S
T
L
Q
A
V
L
D
Site 13
T160
D
S
D
R
G
L
S
T
L
Q
A
V
L
D
S
Site 14
S167
T
L
Q
A
V
L
D
S
A
A
E
K
K
W
Q
Site 15
Y192
N
D
K
K
D
E
M
Y
R
S
L
F
Q
D
L
Site 16
S194
K
K
D
E
M
Y
R
S
L
F
Q
D
L
E
L
Site 17
Y235
K
H
V
K
G
Y
H
Y
I
I
A
N
L
G
F
Site 18
Y265
S
G
F
Q
I
V
D
Y
D
D
S
L
V
S
K
Site 19
S268
Q
I
V
D
Y
D
D
S
L
V
S
K
F
I
E
Site 20
S278
S
K
F
I
E
R
W
S
T
L
E
E
K
E
Y
Site 21
T279
K
F
I
E
R
W
S
T
L
E
E
K
E
Y
P
Site 22
Y285
S
T
L
E
E
K
E
Y
P
G
A
H
T
T
T
Site 23
T291
E
Y
P
G
A
H
T
T
T
I
K
Y
T
S
A
Site 24
T292
Y
P
G
A
H
T
T
T
I
K
Y
T
S
A
L
Site 25
Y295
A
H
T
T
T
I
K
Y
T
S
A
L
T
Y
D
Site 26
Y301
K
Y
T
S
A
L
T
Y
D
A
V
Q
V
M
T
Site 27
S322
R
K
Q
R
I
E
I
S
R
R
G
N
A
G
D
Site 28
Y371
Q
N
G
K
R
I
N
Y
T
I
N
I
M
E
L
Site 29
T372
N
G
K
R
I
N
Y
T
I
N
I
M
E
L
K
Site 30
Y388
N
G
P
R
K
I
G
Y
W
S
E
V
D
K
M
Site 31
T400
D
K
M
V
V
T
L
T
E
L
P
S
G
N
D
Site 32
S404
V
T
L
T
E
L
P
S
G
N
D
T
S
G
L
Site 33
T408
E
L
P
S
G
N
D
T
S
G
L
E
N
K
T
Site 34
Y426
T
T
I
L
E
S
P
Y
V
M
M
K
K
N
H
Site 35
Y461
A
K
H
C
G
F
K
Y
K
L
T
I
V
G
D
Site 36
T464
C
G
F
K
Y
K
L
T
I
V
G
D
G
K
Y
Site 37
Y471
T
I
V
G
D
G
K
Y
G
A
R
D
A
D
T
Site 38
Y490
G
M
V
G
E
L
V
Y
G
K
A
D
I
A
I
Site 39
S513
R
E
E
V
I
D
F
S
K
P
F
M
S
L
G
Site 40
S531
M
I
K
K
P
Q
K
S
K
P
G
V
F
S
F
Site 41
S537
K
S
K
P
G
V
F
S
F
L
D
P
L
A
Y
Site 42
S568
L
F
L
V
S
R
F
S
P
Y
E
W
H
T
E
Site 43
T583
E
F
E
D
G
R
E
T
Q
S
S
E
S
T
N
Site 44
S585
E
D
G
R
E
T
Q
S
S
E
S
T
N
E
F
Site 45
S586
D
G
R
E
T
Q
S
S
E
S
T
N
E
F
G
Site 46
T589
E
T
Q
S
S
E
S
T
N
E
F
G
I
F
N
Site 47
S613
M
Q
Q
G
C
D
I
S
P
R
S
L
S
G
R
Site 48
S616
G
C
D
I
S
P
R
S
L
S
G
R
I
V
G
Site 49
S652
L
T
V
E
R
M
V
S
P
I
E
S
A
E
D
Site 50
S656
R
M
V
S
P
I
E
S
A
E
D
L
S
K
Q
Site 51
S673
I
A
Y
G
T
L
D
S
G
S
T
K
E
F
F
Site 52
S675
Y
G
T
L
D
S
G
S
T
K
E
F
F
R
R
Site 53
S683
T
K
E
F
F
R
R
S
K
I
A
V
F
D
K
Site 54
Y694
V
F
D
K
M
W
T
Y
M
R
S
A
E
P
S
Site 55
S701
Y
M
R
S
A
E
P
S
V
F
V
R
T
T
A
Site 56
S717
G
V
A
R
V
R
K
S
K
G
K
Y
A
Y
L
Site 57
Y721
V
R
K
S
K
G
K
Y
A
Y
L
L
E
S
T
Site 58
Y723
K
S
K
G
K
Y
A
Y
L
L
E
S
T
M
N
Site 59
T741
E
Q
R
K
P
C
D
T
M
K
V
G
G
N
L
Site 60
S750
K
V
G
G
N
L
D
S
K
G
Y
G
I
A
T
Site 61
T757
S
K
G
Y
G
I
A
T
P
K
G
S
S
L
R
Site 62
S762
I
A
T
P
K
G
S
S
L
R
N
A
V
N
L
Site 63
Y789
K
L
K
N
K
W
W
Y
D
K
G
E
C
G
S
Site 64
S801
C
G
S
G
G
G
D
S
K
E
K
T
S
A
L
Site 65
T805
G
G
D
S
K
E
K
T
S
A
L
S
L
S
N
Site 66
S806
G
D
S
K
E
K
T
S
A
L
S
L
S
N
V
Site 67
S809
K
E
K
T
S
A
L
S
L
S
N
V
A
G
V
Site 68
S839
L
I
E
F
C
Y
K
S
R
A
E
A
K
R
M
Site 69
S858
N
A
Q
N
I
N
P
S
S
S
Q
N
S
Q
N
Site 70
S859
A
Q
N
I
N
P
S
S
S
Q
N
S
Q
N
F
Site 71
S860
Q
N
I
N
P
S
S
S
Q
N
S
Q
N
F
A
Site 72
S863
N
P
S
S
S
Q
N
S
Q
N
F
A
T
Y
K
Site 73
Y869
N
S
Q
N
F
A
T
Y
K
E
G
Y
N
V
Y
Site 74
Y876
Y
K
E
G
Y
N
V
Y
G
I
E
S
V
K
I
Site 75
S880
Y
N
V
Y
G
I
E
S
V
K
I
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation