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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GluR3
Full Name:
Glutamate receptor 3
Alias:
GLR3; GLUR3; GluR-3; GLURC; GluR-C; GluR-K3; Glutamate receptor 3; Glutamate receptor ionotropic, AMPA 3; Glutamate receptor, ionotrophic, AMPA 3; GRIA3
Type:
Channel, ligand-gated
Mass (Da):
101157
Number AA:
894
UniProt ID:
P42263
International Prot ID:
IPI00298700
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0030666
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005234
PhosphoSite+
KinaseNET
Biological Process:
GO:0007215
GO:0006811
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
R
Q
K
K
M
G
Q
S
V
L
R
A
V
F
F
Site 2
T44
G
G
L
F
M
R
N
T
V
Q
E
H
S
A
F
Site 3
S49
R
N
T
V
Q
E
H
S
A
F
R
F
A
V
Q
Site 4
Y73
E
K
P
F
H
L
N
Y
H
V
D
H
L
D
S
Site 5
S80
Y
H
V
D
H
L
D
S
S
N
S
F
S
V
T
Site 6
S81
H
V
D
H
L
D
S
S
N
S
F
S
V
T
N
Site 7
S83
D
H
L
D
S
S
N
S
F
S
V
T
N
A
F
Site 8
S85
L
D
S
S
N
S
F
S
V
T
N
A
F
C
S
Site 9
T87
S
S
N
S
F
S
V
T
N
A
F
C
S
Q
F
Site 10
S92
S
V
T
N
A
F
C
S
Q
F
S
R
G
V
Y
Site 11
S128
H
T
S
F
V
T
P
S
F
P
T
D
A
D
V
Site 12
Y156
I
L
S
L
L
G
H
Y
K
W
E
K
F
V
Y
Site 13
Y163
Y
K
W
E
K
F
V
Y
L
Y
D
T
E
R
G
Site 14
Y165
W
E
K
F
V
Y
L
Y
D
T
E
R
G
F
S
Site 15
S172
Y
D
T
E
R
G
F
S
I
L
Q
A
I
M
E
Site 16
Y217
D
R
R
Q
E
K
R
Y
L
I
D
C
E
V
E
Site 17
Y243
L
G
K
H
S
R
G
Y
H
Y
M
L
A
N
L
Site 18
Y245
K
H
S
R
G
Y
H
Y
M
L
A
N
L
G
F
Site 19
Y305
A
K
N
A
P
L
K
Y
T
S
A
L
T
H
D
Site 20
Y323
V
I
A
E
A
F
R
Y
L
R
R
Q
R
V
D
Site 21
S332
R
R
Q
R
V
D
V
S
R
R
G
S
A
G
D
Site 22
S336
V
D
V
S
R
R
G
S
A
G
D
C
L
A
N
Site 23
S349
A
N
P
A
V
P
W
S
Q
G
I
D
I
E
R
Site 24
T374
T
G
N
I
Q
F
D
T
Y
G
R
R
T
N
Y
Site 25
Y375
G
N
I
Q
F
D
T
Y
G
R
R
T
N
Y
T
Site 26
Y381
T
Y
G
R
R
T
N
Y
T
I
D
V
Y
E
M
Site 27
Y386
T
N
Y
T
I
D
V
Y
E
M
K
V
S
G
S
Site 28
S391
D
V
Y
E
M
K
V
S
G
S
R
K
A
G
Y
Site 29
Y398
S
G
S
R
K
A
G
Y
W
N
E
Y
E
R
F
Site 30
Y402
K
A
G
Y
W
N
E
Y
E
R
F
V
P
F
S
Site 31
S409
Y
E
R
F
V
P
F
S
D
Q
Q
I
S
N
D
Site 32
S414
P
F
S
D
Q
Q
I
S
N
D
S
A
S
S
E
Site 33
S417
D
Q
Q
I
S
N
D
S
A
S
S
E
N
R
T
Site 34
S419
Q
I
S
N
D
S
A
S
S
E
N
R
T
I
V
Site 35
T428
E
N
R
T
I
V
V
T
T
I
L
E
S
P
Y
Site 36
Y435
T
T
I
L
E
S
P
Y
V
M
Y
K
K
N
H
Site 37
Y451
Q
L
E
G
N
E
R
Y
E
G
Y
C
V
D
L
Site 38
Y460
G
Y
C
V
D
L
A
Y
E
I
A
K
H
V
R
Site 39
Y470
A
K
H
V
R
I
K
Y
K
L
S
I
V
G
D
Site 40
S473
V
R
I
K
Y
K
L
S
I
V
G
D
G
K
Y
Site 41
Y480
S
I
V
G
D
G
K
Y
G
A
R
D
P
E
T
Site 42
Y499
G
M
V
G
E
L
V
Y
G
R
A
D
I
A
V
Site 43
S522
R
E
E
V
I
D
F
S
K
P
F
M
S
L
G
Site 44
S540
M
I
K
K
P
Q
K
S
K
P
G
V
F
S
F
Site 45
S546
K
S
K
P
G
V
F
S
F
L
D
P
L
A
Y
Site 46
Y553
S
F
L
D
P
L
A
Y
E
I
W
M
C
I
V
Site 47
S577
L
F
L
V
S
R
F
S
P
Y
E
W
H
L
E
Site 48
S595
E
E
P
R
D
P
Q
S
P
P
D
P
P
N
E
Site 49
S624
M
Q
Q
G
C
D
I
S
P
R
S
L
S
G
R
Site 50
S627
G
C
D
I
S
P
R
S
L
S
G
R
I
V
G
Site 51
S663
L
T
V
E
R
M
V
S
P
I
E
S
A
E
D
Site 52
S667
R
M
V
S
P
I
E
S
A
E
D
L
A
K
Q
Site 53
S684
I
A
Y
G
T
L
D
S
G
S
T
K
E
F
F
Site 54
S686
Y
G
T
L
D
S
G
S
T
K
E
F
F
R
R
Site 55
S694
T
K
E
F
F
R
R
S
K
I
A
V
Y
E
K
Site 56
Y699
R
R
S
K
I
A
V
Y
E
K
M
W
S
Y
M
Site 57
Y705
V
Y
E
K
M
W
S
Y
M
K
S
A
E
P
S
Site 58
S708
K
M
W
S
Y
M
K
S
A
E
P
S
V
F
T
Site 59
S712
Y
M
K
S
A
E
P
S
V
F
T
K
T
T
A
Site 60
T715
S
A
E
P
S
V
F
T
K
T
T
A
D
G
V
Site 61
T717
E
P
S
V
F
T
K
T
T
A
D
G
V
A
R
Site 62
S728
G
V
A
R
V
R
K
S
K
G
K
F
A
F
L
Site 63
T752
E
Q
R
K
P
C
D
T
M
K
V
G
G
N
L
Site 64
S761
K
V
G
G
N
L
D
S
K
G
Y
G
V
A
T
Site 65
T768
S
K
G
Y
G
V
A
T
P
K
G
S
A
L
R
Site 66
Y800
K
L
K
N
K
W
W
Y
D
K
G
E
C
G
S
Site 67
S812
C
G
S
G
G
G
D
S
K
D
K
T
S
A
L
Site 68
T816
G
G
D
S
K
D
K
T
S
A
L
S
L
S
N
Site 69
S817
G
D
S
K
D
K
T
S
A
L
S
L
S
N
V
Site 70
S820
K
D
K
T
S
A
L
S
L
S
N
V
A
G
V
Site 71
Y848
V
A
L
I
E
F
C
Y
K
S
R
A
E
S
K
Site 72
S850
L
I
E
F
C
Y
K
S
R
A
E
S
K
R
M
Site 73
S854
C
Y
K
S
R
A
E
S
K
R
M
K
L
T
K
Site 74
T874
K
P
A
P
A
T
N
T
Q
N
Y
A
T
Y
R
Site 75
Y877
P
A
T
N
T
Q
N
Y
A
T
Y
R
E
G
Y
Site 76
T879
T
N
T
Q
N
Y
A
T
Y
R
E
G
Y
N
V
Site 77
Y880
N
T
Q
N
Y
A
T
Y
R
E
G
Y
N
V
Y
Site 78
Y884
Y
A
T
Y
R
E
G
Y
N
V
Y
G
T
E
S
Site 79
Y887
Y
R
E
G
Y
N
V
Y
G
T
E
S
V
K
I
Site 80
S891
Y
N
V
Y
G
T
E
S
V
K
I
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation