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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DPP6
Full Name:
Dipeptidyl aminopeptidase-like protein 6
Alias:
Dipeptidyl aminopeptidase-related; Dipeptidyl peptidase IV-like; Dipeptidylpeptidase 6; Dipeptidylpeptidase VI; DPPX
Type:
Membrane, Integral membrane protein
Mass (Da):
97588
Number AA:
865
UniProt ID:
P42658
International Prot ID:
IPI00252731
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008239
GO:0008236
PhosphoSite+
KinaseNET
Biological Process:
GO:0008219
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
S
L
Y
Q
R
F
T
G
K
I
N
T
S
R
Site 2
T14
R
F
T
G
K
I
N
T
S
R
S
F
P
A
P
Site 3
S17
G
K
I
N
T
S
R
S
F
P
A
P
P
E
A
Site 4
Y71
G
G
R
P
R
F
Q
Y
Q
A
R
S
D
G
D
Site 5
S86
E
E
D
E
L
V
G
S
N
P
P
Q
R
N
W
Site 6
S238
S
L
D
P
P
E
V
S
N
A
K
L
Q
Y
A
Site 7
Y263
F
I
F
E
N
N
I
Y
Y
C
A
H
V
G
K
Site 8
Y264
I
F
E
N
N
I
Y
Y
C
A
H
V
G
K
Q
Site 9
S277
K
Q
A
I
R
V
V
S
T
G
K
E
G
V
I
Site 10
T278
Q
A
I
R
V
V
S
T
G
K
E
G
V
I
Y
Site 11
S529
N
F
N
R
Q
C
L
S
C
D
L
V
E
N
C
Site 12
T563
G
P
G
V
P
M
V
T
V
H
N
T
T
D
K
Site 13
T567
P
M
V
T
V
H
N
T
T
D
K
K
K
M
F
Site 14
Y700
R
T
M
L
K
E
Q
Y
I
D
R
T
R
V
A
Site 15
Y713
V
A
V
F
G
K
D
Y
G
G
Y
L
S
T
Y
Site 16
Y716
F
G
K
D
Y
G
G
Y
L
S
T
Y
I
L
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation