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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WASP
Full Name:
Wiskott-Aldrich syndrome protein
Alias:
Type:
Adapter/scaffold protein
Mass (Da):
52781
Number AA:
502
UniProt ID:
P42768
International Prot ID:
IPI00001545
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015629
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0005083
PhosphoSite+
KinaseNET
Biological Process:
GO:0007596
GO:0006952
GO:0008544
Phosida
TranscriptoNet
STRING
Kinexus Products
Wiskott-Aldrich syndrome protein Y291 phosphosite-specific antibody AB-PN545#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN545#Wiskott-Aldrich syndrome protein (K288-I294, human) pY291 phosphopeptide - Powder PE-04AFC99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AFC99
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y83
K
D
N
P
Q
K
S
Y
F
I
R
L
Y
G
L
Site 2
Y88
K
S
Y
F
I
R
L
Y
G
L
Q
A
G
R
L
Site 3
Y102
L
L
W
E
Q
E
L
Y
S
Q
L
V
Y
S
T
Site 4
S103
L
W
E
Q
E
L
Y
S
Q
L
V
Y
S
T
P
Site 5
Y107
E
L
Y
S
Q
L
V
Y
S
T
P
T
P
F
F
Site 6
T109
Y
S
Q
L
V
Y
S
T
P
T
P
F
F
H
T
Site 7
T116
T
P
T
P
F
F
H
T
F
A
G
D
D
C
Q
Site 8
S153
Q
K
R
N
Q
R
Q
S
G
D
R
R
Q
L
P
Site 9
T164
R
Q
L
P
P
P
P
T
P
A
N
E
E
R
R
Site 10
T208
D
I
Q
N
P
D
I
T
S
S
R
Y
R
G
L
Site 11
S209
I
Q
N
P
D
I
T
S
S
R
Y
R
G
L
P
Site 12
S221
G
L
P
A
P
G
P
S
P
A
D
K
K
R
S
Site 13
S234
R
S
G
K
K
K
I
S
K
A
D
I
G
A
P
Site 14
S242
K
A
D
I
G
A
P
S
G
F
K
H
V
S
H
Site 15
S248
P
S
G
F
K
H
V
S
H
V
G
W
D
P
Q
Site 16
S269
N
L
D
P
D
L
R
S
L
F
S
R
A
G
I
Site 17
S272
P
D
L
R
S
L
F
S
R
A
G
I
S
E
A
Site 18
S277
L
F
S
R
A
G
I
S
E
A
Q
L
T
D
A
Site 19
T282
G
I
S
E
A
Q
L
T
D
A
E
T
S
K
L
Site 20
T286
A
Q
L
T
D
A
E
T
S
K
L
I
Y
D
F
Site 21
S287
Q
L
T
D
A
E
T
S
K
L
I
Y
D
F
I
Site 22
Y291
A
E
T
S
K
L
I
Y
D
F
I
E
D
Q
G
Wiskott-Aldrich syndrome protein Y291 phosphosite-specific antibody AB-PN545#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN545#Wiskott-Aldrich syndrome protein (K288-I294, human) pY291 phosphopeptide - Powder PE-04AFC99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AFC99
Site 23
S320
L
P
P
P
P
P
P
S
R
G
G
N
Q
L
P
Site 24
S339
V
G
G
N
K
G
R
S
G
P
L
P
P
V
P
Site 25
T355
G
I
A
P
P
P
P
T
P
R
G
P
P
P
P
Site 26
T375
P
P
P
P
P
P
A
T
G
R
S
G
P
L
P
Site 27
S378
P
P
P
A
T
G
R
S
G
P
L
P
P
P
P
Site 28
S405
P
P
P
P
P
P
P
S
S
G
N
G
P
A
P
Site 29
S406
P
P
P
P
P
P
S
S
G
N
G
P
A
P
P
Site 30
T447
Q
G
I
Q
L
N
K
T
P
G
A
P
E
S
S
Site 31
S453
K
T
P
G
A
P
E
S
S
A
L
Q
P
P
P
Site 32
S462
A
L
Q
P
P
P
Q
S
S
E
G
L
V
G
A
Site 33
S463
L
Q
P
P
P
Q
S
S
E
G
L
V
G
A
L
Site 34
S483
K
R
S
R
A
I
H
S
S
D
E
G
E
D
Q
Site 35
S484
R
S
R
A
I
H
S
S
D
E
G
E
D
Q
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation