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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GLT1
Full Name:
Excitatory amino acid transporter 2
Alias:
EAA2; EAAT2; GLT-1; Glutamate/aspartate transporter II; SLC1A2; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 (glial high affinity glutamate transporter) member 2; Solute carrier family 1 member 2
Type:
Transport protein
Mass (Da):
62104
Number AA:
574
UniProt ID:
P43004
International Prot ID:
IPI00300020
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0017153
PhosphoSite+
KinaseNET
Biological Process:
GO:0070779
GO:0051938
GO:0006835
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
T
E
G
A
N
N
M
Site 2
T4
_
_
_
_
M
A
S
T
E
G
A
N
N
M
P
Site 3
S21
V
E
V
R
M
H
D
S
H
L
G
S
E
E
P
Site 4
S25
M
H
D
S
H
L
G
S
E
E
P
K
H
R
H
Site 5
S99
L
I
L
P
L
I
I
S
S
L
I
T
G
L
S
Site 6
S100
I
L
P
L
I
I
S
S
L
I
T
G
L
S
G
Site 7
S113
S
G
L
D
A
K
A
S
G
R
L
G
T
R
A
Site 8
T118
K
A
S
G
R
L
G
T
R
A
M
V
Y
Y
M
Site 9
Y123
L
G
T
R
A
M
V
Y
Y
M
S
T
T
I
I
Site 10
Y124
G
T
R
A
M
V
Y
Y
M
S
T
T
I
I
A
Site 11
T371
S
A
G
T
L
P
V
T
F
R
C
L
E
E
N
Site 12
Y404
N
M
D
G
T
A
L
Y
E
A
V
A
A
I
F
Site 13
T479
W
L
L
D
R
M
R
T
S
V
N
V
V
G
D
Site 14
S480
L
L
D
R
M
R
T
S
V
N
V
V
G
D
S
Site 15
S487
S
V
N
V
V
G
D
S
F
G
A
G
I
V
Y
Site 16
Y494
S
F
G
A
G
I
V
Y
H
L
S
K
S
E
L
Site 17
S497
A
G
I
V
Y
H
L
S
K
S
E
L
D
T
I
Site 18
S499
I
V
Y
H
L
S
K
S
E
L
D
T
I
D
S
Site 19
T503
L
S
K
S
E
L
D
T
I
D
S
Q
H
R
V
Site 20
S506
S
E
L
D
T
I
D
S
Q
H
R
V
H
E
D
Site 21
T519
E
D
I
E
M
T
K
T
Q
S
I
Y
D
D
M
Site 22
S521
I
E
M
T
K
T
Q
S
I
Y
D
D
M
K
N
Site 23
Y523
M
T
K
T
Q
S
I
Y
D
D
M
K
N
H
R
Site 24
Y539
S
N
S
N
Q
C
V
Y
A
A
H
N
S
V
I
Site 25
S544
C
V
Y
A
A
H
N
S
V
I
V
D
E
C
K
Site 26
S560
T
L
A
A
N
G
K
S
A
D
C
S
V
E
E
Site 27
S564
N
G
K
S
A
D
C
S
V
E
E
E
P
W
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation