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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC1A1
Full Name:
Excitatory amino acid transporter 3
Alias:
EAA3; EAAC1; EAAT3; Excitatory amino-acid carrier 1; Neuronal and epithelial glutamate transporter; Sodium-dependent glutamate/aspartate transporter 3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag) member 1
Type:
Membrane protein, integral; Transporter
Mass (Da):
57100
Number AA:
524
UniProt ID:
P43005
International Prot ID:
IPI00015475
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0017153
PhosphoSite+
KinaseNET
Biological Process:
GO:0070779
GO:0051938
GO:0006835
Phosida
TranscriptoNet
STRING
Kinexus Products
Excitatory amino acid transporter 3 pan-specific antibody AB-NN244-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN244-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S42
G
V
L
V
R
E
H
S
N
L
S
T
L
E
K
Site 2
S45
V
R
E
H
S
N
L
S
T
L
E
K
F
Y
F
Site 3
T46
R
E
H
S
N
L
S
T
L
E
K
F
Y
F
A
Site 4
Y51
L
S
T
L
E
K
F
Y
F
A
F
P
G
E
I
Site 5
Y162
V
Q
A
C
F
Q
Q
Y
K
T
K
R
E
E
V
Site 6
S193
A
V
M
T
T
A
I
S
K
N
K
T
K
E
Y
Site 7
T340
S
S
A
T
L
P
V
T
F
R
C
A
E
E
N
Site 8
T355
N
Q
V
D
K
R
I
T
R
F
V
L
P
V
G
Site 9
S466
T
G
I
V
E
K
L
S
K
K
E
L
E
Q
M
Site 10
S476
E
L
E
Q
M
D
V
S
S
E
V
N
I
V
N
Site 11
S477
L
E
Q
M
D
V
S
S
E
V
N
I
V
N
P
Site 12
S497
T
I
L
D
N
E
D
S
D
T
K
K
S
Y
V
Site 13
T499
L
D
N
E
D
S
D
T
K
K
S
Y
V
N
G
Site 14
S502
E
D
S
D
T
K
K
S
Y
V
N
G
G
F
A
Site 15
Y503
D
S
D
T
K
K
S
Y
V
N
G
G
F
A
V
Site 16
S513
G
G
F
A
V
D
K
S
D
T
I
S
F
T
Q
Site 17
T515
F
A
V
D
K
S
D
T
I
S
F
T
Q
T
S
Site 18
S517
V
D
K
S
D
T
I
S
F
T
Q
T
S
Q
F
Site 19
T519
K
S
D
T
I
S
F
T
Q
T
S
Q
F
_
_
Site 20
S522
T
I
S
F
T
Q
T
S
Q
F
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation