PhosphoNET

           
Protein Info 
   
Short Name:  PTGER2
Full Name:  Prostaglandin E2 receptor EP2 subtype
Alias:  Prostanoid EP2 receptor
Type: 
Mass (Da):  39761
Number AA:  358
UniProt ID:  P43116
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MGNASNDSQSEDCET
Site 2S10NASNDSQSEDCETRQ
Site 3T15SQSEDCETRQWLPPG
Site 4S24QWLPPGESPAISSVM
Site 5S33AISSVMFSAGVLGNL
Site 6S57WRGDVGCSAGRRSSL
Site 7S62GCSAGRRSSLSLFHV
Site 8T98ASYARNQTLVALAPE
Site 9Y142YLSIGHPYFYQRRVS
Site 10Y144SIGHPYFYQRRVSRS
Site 11S149YFYQRRVSRSGGLAV
Site 12S151YQRRVSRSGGLAVLP
Site 13Y178PLLDYGQYVQYCPGT
Site 14Y196IRHGRTAYLQLYATL
Site 15S229LIRMHRRSRRSRCGP
Site 16S232MHRRSRRSRCGPSLG
Site 17S237RRSRCGPSLGSGRGG
Site 18S240RCGPSLGSGRGGPGA
Site 19S255RRRGERVSMAEETDH
Site 20Y285LPFTIFAYMNETSSR
Site 21T338CCRISLRTQDATQTS
Site 22T342SLRTQDATQTSCSTQ
Site 23T344RTQDATQTSCSTQSD
Site 24S345TQDATQTSCSTQSDA
Site 25S350QTSCSTQSDASKQAD
Site 26S353CSTQSDASKQADL__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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