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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MATR3
Full Name:
Matrin-3
Alias:
KIAA0723; MAT3; MGC9105
Type:
RNA binding protein; RNA processing
Mass (Da):
94623
Number AA:
847
UniProt ID:
P43243
International Prot ID:
IPI00017297
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005637
GO:0016363
GO:0005637
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
S
K
S
F
Q
Q
S
S
L
S
Site 2
S8
M
S
K
S
F
Q
Q
S
S
L
S
R
D
S
Q
Site 3
S9
S
K
S
F
Q
Q
S
S
L
S
R
D
S
Q
G
Site 4
S11
S
F
Q
Q
S
S
L
S
R
D
S
Q
G
H
G
Site 5
S14
Q
S
S
L
S
R
D
S
Q
G
H
G
R
D
L
Site 6
S22
Q
G
H
G
R
D
L
S
A
A
G
I
G
L
L
Site 7
S41
Q
S
L
S
M
P
A
S
L
G
R
M
N
Q
G
Site 8
T49
L
G
R
M
N
Q
G
T
A
R
L
A
S
L
M
Site 9
S54
Q
G
T
A
R
L
A
S
L
M
N
L
G
M
S
Site 10
S63
M
N
L
G
M
S
S
S
L
N
Q
Q
G
A
H
Site 11
S71
L
N
Q
Q
G
A
H
S
A
L
S
S
A
S
T
Site 12
S74
Q
G
A
H
S
A
L
S
S
A
S
T
S
S
H
Site 13
S75
G
A
H
S
A
L
S
S
A
S
T
S
S
H
N
Site 14
S77
H
S
A
L
S
S
A
S
T
S
S
H
N
L
Q
Site 15
T78
S
A
L
S
S
A
S
T
S
S
H
N
L
Q
S
Site 16
S79
A
L
S
S
A
S
T
S
S
H
N
L
Q
S
I
Site 17
S80
L
S
S
A
S
T
S
S
H
N
L
Q
S
I
F
Site 18
S85
T
S
S
H
N
L
Q
S
I
F
N
I
G
S
R
Site 19
S91
Q
S
I
F
N
I
G
S
R
G
P
L
P
L
S
Site 20
S98
S
R
G
P
L
P
L
S
S
Q
H
R
G
D
A
Site 21
S99
R
G
P
L
P
L
S
S
Q
H
R
G
D
A
D
Site 22
S109
R
G
D
A
D
Q
A
S
N
I
L
A
S
F
G
Site 23
S114
Q
A
S
N
I
L
A
S
F
G
L
S
A
R
D
Site 24
S118
I
L
A
S
F
G
L
S
A
R
D
L
D
E
L
Site 25
S126
A
R
D
L
D
E
L
S
R
Y
P
E
D
K
I
Site 26
Y128
D
L
D
E
L
S
R
Y
P
E
D
K
I
T
P
Site 27
T134
R
Y
P
E
D
K
I
T
P
E
N
L
P
Q
I
Site 28
T150
L
Q
L
K
R
R
R
T
E
E
G
P
T
L
S
Site 29
T155
R
R
T
E
E
G
P
T
L
S
Y
G
R
D
G
Site 30
S157
T
E
E
G
P
T
L
S
Y
G
R
D
G
R
S
Site 31
Y158
E
E
G
P
T
L
S
Y
G
R
D
G
R
S
A
Site 32
S164
S
Y
G
R
D
G
R
S
A
T
R
E
P
P
Y
Site 33
T166
G
R
D
G
R
S
A
T
R
E
P
P
Y
R
V
Site 34
Y171
S
A
T
R
E
P
P
Y
R
V
P
R
D
D
W
Site 35
S188
K
R
H
F
R
R
D
S
F
D
D
R
G
P
S
Site 36
S195
S
F
D
D
R
G
P
S
L
N
P
V
L
D
Y
Site 37
Y202
S
L
N
P
V
L
D
Y
D
H
G
S
R
S
Q
Site 38
S206
V
L
D
Y
D
H
G
S
R
S
Q
E
S
G
Y
Site 39
S208
D
Y
D
H
G
S
R
S
Q
E
S
G
Y
Y
D
Site 40
S211
H
G
S
R
S
Q
E
S
G
Y
Y
D
R
M
D
Site 41
Y213
S
R
S
Q
E
S
G
Y
Y
D
R
M
D
Y
E
Site 42
Y214
R
S
Q
E
S
G
Y
Y
D
R
M
D
Y
E
D
Site 43
Y219
G
Y
Y
D
R
M
D
Y
E
D
D
R
L
R
D
Site 44
S234
G
E
R
C
R
D
D
S
F
F
G
E
T
S
H
Site 45
T239
D
D
S
F
F
G
E
T
S
H
N
Y
H
K
F
Site 46
S240
D
S
F
F
G
E
T
S
H
N
Y
H
K
F
D
Site 47
Y243
F
G
E
T
S
H
N
Y
H
K
F
D
S
E
Y
Site 48
S248
H
N
Y
H
K
F
D
S
E
Y
E
R
M
G
R
Site 49
Y250
Y
H
K
F
D
S
E
Y
E
R
M
G
R
G
P
Site 50
S264
P
G
P
L
Q
E
R
S
L
F
E
K
K
R
G
Site 51
S275
K
K
R
G
A
P
P
S
S
N
I
E
D
F
H
Site 52
S276
K
R
G
A
P
P
S
S
N
I
E
D
F
H
G
Site 53
S314
S
Q
H
I
N
G
A
S
H
S
R
R
C
Q
L
Site 54
S316
H
I
N
G
A
S
H
S
R
R
C
Q
L
L
L
Site 55
Y326
C
Q
L
L
L
E
I
Y
P
E
W
N
P
D
N
Site 56
S348
D
P
F
M
L
Q
Q
S
T
N
P
A
P
G
I
Site 57
T396
M
Q
K
G
R
V
E
T
S
R
V
V
H
I
M
Site 58
S397
Q
K
G
R
V
E
T
S
R
V
V
H
I
M
D
Site 59
Y453
D
A
Q
A
A
V
D
Y
Y
T
T
T
P
A
L
Site 60
S471
K
P
V
R
V
H
L
S
Q
K
Y
K
R
I
K
Site 61
Y474
R
V
H
L
S
Q
K
Y
K
R
I
K
K
P
E
Site 62
S501
L
G
R
V
I
H
L
S
N
L
P
H
S
G
Y
Site 63
S506
H
L
S
N
L
P
H
S
G
Y
S
D
S
A
V
Site 64
Y508
S
N
L
P
H
S
G
Y
S
D
S
A
V
L
K
Site 65
S509
N
L
P
H
S
G
Y
S
D
S
A
V
L
K
L
Site 66
S511
P
H
S
G
Y
S
D
S
A
V
L
K
L
A
E
Site 67
Y520
V
L
K
L
A
E
P
Y
G
K
I
K
N
Y
I
Site 68
Y526
P
Y
G
K
I
K
N
Y
I
L
M
R
M
K
S
Site 69
S533
Y
I
L
M
R
M
K
S
Q
A
F
I
E
M
E
Site 70
S569
R
C
V
K
V
D
L
S
E
K
Y
K
K
L
V
Site 71
S592
D
L
L
K
K
D
K
S
R
K
R
S
Y
S
P
Site 72
S596
K
D
K
S
R
K
R
S
Y
S
P
D
G
K
E
Site 73
Y597
D
K
S
R
K
R
S
Y
S
P
D
G
K
E
S
Site 74
S598
K
S
R
K
R
S
Y
S
P
D
G
K
E
S
P
Site 75
S604
Y
S
P
D
G
K
E
S
P
S
D
K
K
S
K
Site 76
S606
P
D
G
K
E
S
P
S
D
K
K
S
K
T
D
Site 77
S610
E
S
P
S
D
K
K
S
K
T
D
G
S
Q
K
Site 78
T612
P
S
D
K
K
S
K
T
D
G
S
Q
K
T
E
Site 79
S615
K
K
S
K
T
D
G
S
Q
K
T
E
S
S
T
Site 80
T618
K
T
D
G
S
Q
K
T
E
S
S
T
E
G
K
Site 81
S620
D
G
S
Q
K
T
E
S
S
T
E
G
K
E
Q
Site 82
S621
G
S
Q
K
T
E
S
S
T
E
G
K
E
Q
E
Site 83
T622
S
Q
K
T
E
S
S
T
E
G
K
E
Q
E
E
Site 84
S631
G
K
E
Q
E
E
K
S
G
E
D
G
E
K
D
Site 85
T639
G
E
D
G
E
K
D
T
K
D
D
Q
T
E
Q
Site 86
T644
K
D
T
K
D
D
Q
T
E
Q
E
P
N
M
L
Site 87
S654
E
P
N
M
L
L
E
S
E
D
E
L
L
V
D
Site 88
S671
E
A
A
A
L
L
E
S
G
S
S
V
G
D
E
Site 89
S673
A
A
L
L
E
S
G
S
S
V
G
D
E
T
D
Site 90
S674
A
L
L
E
S
G
S
S
V
G
D
E
T
D
L
Site 91
T679
G
S
S
V
G
D
E
T
D
L
A
N
L
G
D
Site 92
S689
A
N
L
G
D
V
A
S
D
G
K
K
E
P
S
Site 93
S696
S
D
G
K
K
E
P
S
D
K
A
V
K
K
D
Site 94
T741
G
I
K
N
E
E
N
T
E
P
G
A
E
S
S
Site 95
S747
N
T
E
P
G
A
E
S
S
E
N
A
D
D
P
Site 96
S748
T
E
P
G
A
E
S
S
E
N
A
D
D
P
N
Site 97
S766
S
E
N
A
D
G
Q
S
D
E
N
K
D
D
Y
Site 98
Y773
S
D
E
N
K
D
D
Y
T
I
P
D
E
Y
R
Site 99
T774
D
E
N
K
D
D
Y
T
I
P
D
E
Y
R
I
Site 100
Y779
D
Y
T
I
P
D
E
Y
R
I
G
P
Y
Q
P
Site 101
Y784
D
E
Y
R
I
G
P
Y
Q
P
N
V
P
V
G
Site 102
Y794
N
V
P
V
G
I
D
Y
V
I
P
K
T
G
F
Site 103
Y802
V
I
P
K
T
G
F
Y
C
K
L
C
S
L
F
Site 104
T811
K
L
C
S
L
F
Y
T
N
E
E
V
A
K
N
Site 105
T819
N
E
E
V
A
K
N
T
H
C
S
S
L
P
H
Site 106
S823
A
K
N
T
H
C
S
S
L
P
H
Y
Q
K
L
Site 107
Y827
H
C
S
S
L
P
H
Y
Q
K
L
K
K
F
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation