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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ETV4
Full Name:
ETS translocation variant 4
Alias:
Adenovirus E1A enhancer-binding protein; E1AF; E1A-F
Type:
Transcription protein
Mass (Da):
53938
Number AA:
484
UniProt ID:
P43268
International Prot ID:
IPI00017382
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0005730
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0016563
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
E
R
R
M
K
A
G
Y
L
D
Q
Q
V
P
Y
Site 2
Y16
Y
L
D
Q
Q
V
P
Y
T
F
S
S
K
S
P
Site 3
T17
L
D
Q
Q
V
P
Y
T
F
S
S
K
S
P
G
Site 4
S19
Q
Q
V
P
Y
T
F
S
S
K
S
P
G
N
G
Site 5
S20
Q
V
P
Y
T
F
S
S
K
S
P
G
N
G
S
Site 6
S22
P
Y
T
F
S
S
K
S
P
G
N
G
S
L
R
Site 7
S27
S
K
S
P
G
N
G
S
L
R
E
A
L
I
G
Site 8
S44
G
K
L
M
D
P
G
S
L
P
P
L
D
S
E
Site 9
S50
G
S
L
P
P
L
D
S
E
D
L
F
Q
D
L
Site 10
S73
A
E
A
Q
V
P
D
S
D
E
Q
F
V
P
D
Site 11
S83
Q
F
V
P
D
F
H
S
E
N
L
A
F
H
S
Site 12
S90
S
E
N
L
A
F
H
S
P
T
T
R
I
K
K
Site 13
S101
R
I
K
K
E
P
Q
S
P
R
T
D
P
A
L
Site 14
T104
K
E
P
Q
S
P
R
T
D
P
A
L
S
C
S
Site 15
S109
P
R
T
D
P
A
L
S
C
S
R
K
P
P
L
Site 16
S111
T
D
P
A
L
S
C
S
R
K
P
P
L
P
Y
Site 17
Y118
S
R
K
P
P
L
P
Y
H
H
G
E
Q
C
L
Site 18
Y126
H
H
G
E
Q
C
L
Y
S
S
A
Y
D
P
P
Site 19
S127
H
G
E
Q
C
L
Y
S
S
A
Y
D
P
P
R
Site 20
S128
G
E
Q
C
L
Y
S
S
A
Y
D
P
P
R
Q
Site 21
Y130
Q
C
L
Y
S
S
A
Y
D
P
P
R
Q
I
A
Site 22
S140
P
R
Q
I
A
I
K
S
P
A
P
G
A
L
G
Site 23
S149
A
P
G
A
L
G
Q
S
P
L
Q
P
F
P
R
Site 24
S165
E
Q
R
N
F
L
R
S
S
G
T
S
Q
P
H
Site 25
S166
Q
R
N
F
L
R
S
S
G
T
S
Q
P
H
P
Site 26
T168
N
F
L
R
S
S
G
T
S
Q
P
H
P
G
H
Site 27
S169
F
L
R
S
S
G
T
S
Q
P
H
P
G
H
G
Site 28
Y177
Q
P
H
P
G
H
G
Y
L
G
E
H
S
S
V
Site 29
S183
G
Y
L
G
E
H
S
S
V
F
Q
Q
P
L
D
Site 30
S194
Q
P
L
D
I
C
H
S
F
T
S
Q
G
G
G
Site 31
S197
D
I
C
H
S
F
T
S
Q
G
G
G
R
E
P
Site 32
S214
A
P
Y
Q
H
Q
L
S
E
P
C
P
P
Y
P
Site 33
Y220
L
S
E
P
C
P
P
Y
P
Q
Q
S
F
K
Q
Site 34
Y229
Q
Q
S
F
K
Q
E
Y
H
D
P
L
Y
E
Q
Site 35
Y234
Q
E
Y
H
D
P
L
Y
E
Q
A
G
Q
P
A
Site 36
Y268
Q
E
Q
T
D
F
A
Y
D
S
D
V
T
G
C
Site 37
S270
Q
T
D
F
A
Y
D
S
D
V
T
G
C
A
S
Site 38
T282
C
A
S
M
Y
L
H
T
E
G
F
S
G
P
S
Site 39
S289
T
E
G
F
S
G
P
S
P
G
D
G
A
M
G
Site 40
Y297
P
G
D
G
A
M
G
Y
G
Y
E
K
P
L
R
Site 41
Y299
D
G
A
M
G
Y
G
Y
E
K
P
L
R
P
F
Site 42
Y335
A
F
R
E
G
P
P
Y
Q
R
R
G
A
L
Q
Site 43
Y392
K
N
R
P
A
M
N
Y
D
K
L
S
R
S
L
Site 44
S398
N
Y
D
K
L
S
R
S
L
R
Y
Y
Y
E
K
Site 45
Y402
L
S
R
S
L
R
Y
Y
Y
E
K
G
I
M
Q
Site 46
Y403
S
R
S
L
R
Y
Y
Y
E
K
G
I
M
Q
K
Site 47
Y416
Q
K
V
A
G
E
R
Y
V
Y
K
F
V
C
E
Site 48
Y418
V
A
G
E
R
Y
V
Y
K
F
V
C
E
P
E
Site 49
S429
C
E
P
E
A
L
F
S
L
A
F
P
D
N
Q
Site 50
S449
A
E
F
D
R
P
V
S
E
E
D
T
V
P
L
Site 51
T453
R
P
V
S
E
E
D
T
V
P
L
S
H
L
D
Site 52
S457
E
E
D
T
V
P
L
S
H
L
D
E
S
P
A
Site 53
S462
P
L
S
H
L
D
E
S
P
A
Y
L
P
E
L
Site 54
Y465
H
L
D
E
S
P
A
Y
L
P
E
L
A
G
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation