PhosphoNET

           
Protein Info 
   
Short Name:  MAGEA2
Full Name:  Melanoma-associated antigen 2
Alias:  MAGE-2 antigen
Type: 
Mass (Da):  35037
Number AA:  314
UniProt ID:  P43356
International Prot ID:  IPI00018038
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S7_MPLEQRSQHCKPEE
Site 2T33VGAQAPATEEQQTAS
Site 3T38PATEEQQTASSSSTL
Site 4S40TEEQQTASSSSTLVE
Site 5S58GEVPAADSPSPPHSP
Site 6S60VPAADSPSPPHSPQG
Site 7S64DSPSPPHSPQGASSF
Site 8S70HSPQGASSFSTTINY
Site 9T73QGASSFSTTINYTLW
Site 10T74GASSFSTTINYTLWR
Site 11Y77SFSTTINYTLWRQSD
Site 12S83NYTLWRQSDEGSSNQ
Site 13S87WRQSDEGSSNQEEEG
Site 14S103RMFPDLESEFQAAIS
Site 15T131YRAREPVTKAEMLES
Site 16S138TKAEMLESVLRNCQD
Site 17S226EKIWEELSMLEVFEG
Site 18S237VFEGREDSVFAHPRK
Site 19Y255QDLVQENYLEYRQVP
Site 20Y258VQENYLEYRQVPGSD
Site 21S264EYRQVPGSDPACYEF
Site 22Y269PGSDPACYEFLWGPR
Site 23S282PRALIETSYVKVLHH
Site 24Y283RALIETSYVKVLHHT
Site 25S300IGGEPHISYPPLHER
Site 26Y301GGEPHISYPPLHERA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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