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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MAGEA8
Full Name:
Melanoma-associated antigen 8
Alias:
Cancer/testis antigen 1.8;MAGE-8 antigen
Type:
Mass (Da):
35215
Number AA:
318
UniProt ID:
P43361
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
L
L
G
Q
K
S
Q
R
Y
K
A
E
E
Site 2
Y10
L
G
Q
K
S
Q
R
Y
K
A
E
E
G
L
Q
Site 3
S40
A
E
E
Q
K
A
A
S
S
S
S
T
L
I
M
Site 4
T49
S
S
T
L
I
M
G
T
L
E
E
V
T
D
S
Site 5
T54
M
G
T
L
E
E
V
T
D
S
G
S
P
S
P
Site 6
S56
T
L
E
E
V
T
D
S
G
S
P
S
P
P
Q
Site 7
S58
E
E
V
T
D
S
G
S
P
S
P
P
Q
S
P
Site 8
S60
V
T
D
S
G
S
P
S
P
P
Q
S
P
E
G
Site 9
S64
G
S
P
S
P
P
Q
S
P
E
G
A
S
S
S
Site 10
S70
Q
S
P
E
G
A
S
S
S
L
T
V
T
D
S
Site 11
S71
S
P
E
G
A
S
S
S
L
T
V
T
D
S
T
Site 12
T73
E
G
A
S
S
S
L
T
V
T
D
S
T
L
W
Site 13
T75
A
S
S
S
L
T
V
T
D
S
T
L
W
S
Q
Site 14
S77
S
S
L
T
V
T
D
S
T
L
W
S
Q
S
D
Site 15
T78
S
L
T
V
T
D
S
T
L
W
S
Q
S
D
E
Site 16
S81
V
T
D
S
T
L
W
S
Q
S
D
E
G
S
S
Site 17
S83
D
S
T
L
W
S
Q
S
D
E
G
S
S
S
N
Site 18
S87
W
S
Q
S
D
E
G
S
S
S
N
E
E
E
G
Site 19
S89
Q
S
D
E
G
S
S
S
N
E
E
E
G
P
S
Site 20
S96
S
N
E
E
E
G
P
S
T
S
P
D
P
A
H
Site 21
T97
N
E
E
E
G
P
S
T
S
P
D
P
A
H
L
Site 22
S98
E
E
E
G
P
S
T
S
P
D
P
A
H
L
E
Site 23
S106
P
D
P
A
H
L
E
S
L
F
R
E
A
L
D
Site 24
Y127
V
R
F
L
L
R
K
Y
Q
I
K
E
P
V
T
Site 25
S141
T
K
A
E
M
L
E
S
V
I
K
N
Y
K
N
Site 26
Y146
L
E
S
V
I
K
N
Y
K
N
H
F
P
D
I
Site 27
S198
G
L
L
G
D
D
Q
S
T
P
K
T
G
L
L
Site 28
T199
L
L
G
D
D
Q
S
T
P
K
T
G
L
L
I
Site 29
S229
E
A
I
W
E
A
L
S
V
M
G
L
Y
D
G
Site 30
Y234
A
L
S
V
M
G
L
Y
D
G
R
E
H
S
V
Site 31
S240
L
Y
D
G
R
E
H
S
V
Y
W
K
L
R
K
Site 32
Y242
D
G
R
E
H
S
V
Y
W
K
L
R
K
L
L
Site 33
T250
W
K
L
R
K
L
L
T
Q
E
W
V
Q
E
N
Site 34
Y258
Q
E
W
V
Q
E
N
Y
L
E
Y
R
Q
A
P
Site 35
S267
E
Y
R
Q
A
P
G
S
D
P
V
R
Y
E
F
Site 36
Y272
P
G
S
D
P
V
R
Y
E
F
L
W
G
P
R
Site 37
T284
G
P
R
A
L
A
E
T
S
Y
V
K
V
L
E
Site 38
S303
V
N
A
R
V
R
I
S
Y
P
S
L
H
E
E
Site 39
Y304
N
A
R
V
R
I
S
Y
P
S
L
H
E
E
A
Site 40
S306
R
V
R
I
S
Y
P
S
L
H
E
E
A
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation