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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GATA4
Full Name:
Transcription factor GATA-4
Alias:
DNA binding protein GATA-GT2; GAT4; GATA binding factor-4; GATA binding protein 4; GATA-4
Type:
Transcription protein
Mass (Da):
44627
Number AA:
442
UniProt ID:
P43694
International Prot ID:
IPI00020064
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003704
GO:0033613
PhosphoSite+
KinaseNET
Biological Process:
GO:0007267
GO:0048617
GO:0035054
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
H
G
P
P
P
G
A
Y
E
A
G
G
P
G
A
Site 2
S35
H
G
A
G
A
A
S
S
P
V
Y
V
P
T
P
Site 3
Y38
G
A
A
S
S
P
V
Y
V
P
T
P
R
V
P
Site 4
T41
S
S
P
V
Y
V
P
T
P
R
V
P
S
S
V
Site 5
S61
L
Q
G
G
G
A
G
S
A
S
G
G
A
S
G
Site 6
S63
G
G
G
A
G
S
A
S
G
G
A
S
G
G
S
Site 7
S67
G
S
A
S
G
G
A
S
G
G
S
S
G
G
A
Site 8
S70
S
G
G
A
S
G
G
S
S
G
G
A
A
S
G
Site 9
S71
G
G
A
S
G
G
S
S
G
G
A
A
S
G
A
Site 10
S76
G
S
S
G
G
A
A
S
G
A
G
P
G
T
Q
Site 11
T82
A
S
G
A
G
P
G
T
Q
Q
G
S
P
G
W
Site 12
S86
G
P
G
T
Q
Q
G
S
P
G
W
S
Q
A
G
Site 13
S90
Q
Q
G
S
P
G
W
S
Q
A
G
A
D
G
A
Site 14
Y99
A
G
A
D
G
A
A
Y
T
P
P
P
V
S
P
Site 15
T100
G
A
D
G
A
A
Y
T
P
P
P
V
S
P
R
Site 16
S105
A
Y
T
P
P
P
V
S
P
R
F
S
F
P
G
Site 17
S109
P
P
V
S
P
R
F
S
F
P
G
T
T
G
S
Site 18
Y132
A
A
R
E
A
A
A
Y
S
S
G
G
G
A
A
Site 19
Y149
G
L
A
G
R
E
Q
Y
G
R
A
G
F
A
G
Site 20
S157
G
R
A
G
F
A
G
S
Y
S
S
P
Y
P
A
Site 21
Y158
R
A
G
F
A
G
S
Y
S
S
P
Y
P
A
Y
Site 22
S159
A
G
F
A
G
S
Y
S
S
P
Y
P
A
Y
M
Site 23
S160
G
F
A
G
S
Y
S
S
P
Y
P
A
Y
M
A
Site 24
Y162
A
G
S
Y
S
S
P
Y
P
A
Y
M
A
D
V
Site 25
Y165
Y
S
S
P
Y
P
A
Y
M
A
D
V
G
A
S
Site 26
S191
F
D
S
P
V
L
H
S
L
P
G
R
A
N
P
Site 27
T225
V
N
C
G
A
M
S
T
P
L
W
R
R
D
G
Site 28
T233
P
L
W
R
R
D
G
T
G
H
Y
L
C
N
A
Site 29
Y236
R
R
D
G
T
G
H
Y
L
C
N
A
C
G
L
Site 30
Y244
L
C
N
A
C
G
L
Y
H
K
M
N
G
I
N
Site 31
S262
I
K
P
Q
R
R
L
S
A
S
R
R
V
G
L
Site 32
S264
P
Q
R
R
L
S
A
S
R
R
V
G
L
S
C
Site 33
S270
A
S
R
R
V
G
L
S
C
A
N
C
Q
T
T
Site 34
T317
M
R
K
E
G
I
Q
T
R
K
R
K
P
K
N
Site 35
S328
K
P
K
N
L
N
K
S
K
T
P
A
A
P
S
Site 36
T330
K
N
L
N
K
S
K
T
P
A
A
P
S
G
S
Site 37
S335
S
K
T
P
A
A
P
S
G
S
E
S
L
P
P
Site 38
S337
T
P
A
A
P
S
G
S
E
S
L
P
P
A
S
Site 39
S339
A
A
P
S
G
S
E
S
L
P
P
A
S
G
A
Site 40
S344
S
E
S
L
P
P
A
S
G
A
S
S
N
S
S
Site 41
S347
L
P
P
A
S
G
A
S
S
N
S
S
N
A
T
Site 42
S348
P
P
A
S
G
A
S
S
N
S
S
N
A
T
T
Site 43
S350
A
S
G
A
S
S
N
S
S
N
A
T
T
S
S
Site 44
S351
S
G
A
S
S
N
S
S
N
A
T
T
S
S
S
Site 45
T354
S
S
N
S
S
N
A
T
T
S
S
S
E
E
M
Site 46
T355
S
N
S
S
N
A
T
T
S
S
S
E
E
M
R
Site 47
S357
S
S
N
A
T
T
S
S
S
E
E
M
R
P
I
Site 48
S358
S
N
A
T
T
S
S
S
E
E
M
R
P
I
K
Site 49
T366
E
E
M
R
P
I
K
T
E
P
G
L
S
S
H
Site 50
S371
I
K
T
E
P
G
L
S
S
H
Y
G
H
S
S
Site 51
S372
K
T
E
P
G
L
S
S
H
Y
G
H
S
S
S
Site 52
Y374
E
P
G
L
S
S
H
Y
G
H
S
S
S
V
S
Site 53
S377
L
S
S
H
Y
G
H
S
S
S
V
S
Q
T
F
Site 54
S378
S
S
H
Y
G
H
S
S
S
V
S
Q
T
F
S
Site 55
S379
S
H
Y
G
H
S
S
S
V
S
Q
T
F
S
V
Site 56
S381
Y
G
H
S
S
S
V
S
Q
T
F
S
V
S
A
Site 57
T383
H
S
S
S
V
S
Q
T
F
S
V
S
A
M
S
Site 58
S385
S
S
V
S
Q
T
F
S
V
S
A
M
S
G
H
Site 59
S387
V
S
Q
T
F
S
V
S
A
M
S
G
H
G
P
Site 60
S390
T
F
S
V
S
A
M
S
G
H
G
P
S
I
H
Site 61
Y410
L
K
L
S
P
Q
G
Y
A
S
P
V
S
Q
S
Site 62
S412
L
S
P
Q
G
Y
A
S
P
V
S
Q
S
P
Q
Site 63
S415
Q
G
Y
A
S
P
V
S
Q
S
P
Q
T
S
S
Site 64
S417
Y
A
S
P
V
S
Q
S
P
Q
T
S
S
K
Q
Site 65
T420
P
V
S
Q
S
P
Q
T
S
S
K
Q
D
S
W
Site 66
S421
V
S
Q
S
P
Q
T
S
S
K
Q
D
S
W
N
Site 67
S422
S
Q
S
P
Q
T
S
S
K
Q
D
S
W
N
S
Site 68
S426
Q
T
S
S
K
Q
D
S
W
N
S
L
V
L
A
Site 69
S429
S
K
Q
D
S
W
N
S
L
V
L
A
D
S
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation