PhosphoNET

           
Protein Info 
   
Short Name:  PPIC
Full Name:  Peptidyl-prolyl cis-trans isomerase C
Alias:  Cyclophilin C
Type: 
Mass (Da):  22745
Number AA:  212
UniProt ID:  P45877
International Prot ID:  IPI00024129
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0044424  GO:0044464 Uniprot OncoNet
Molecular Function:  GO:0003755  GO:0003824  GO:0005488 PhosphoSite+ KinaseNET
Biological Process:  GO:0006457  GO:0007154  GO:0007165 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S35GFRKRGPSVTAKVFF
Site 2T37RKRGPSVTAKVFFDV
Site 3Y82TGEKGYGYKGSKFHR
Site 4S85KGYGYKGSKFHRVIK
Site 5T102MIQGGDITTGDGTGG
Site 6T103IQGGDITTGDGTGGV
Site 7T107DITTGDGTGGVSIYG
Site 8S111GDGTGGVSIYGETFP
Site 9Y113GTGGVSIYGETFPDE
Site 10T116GVSIYGETFPDENFK
Site 11Y127ENFKLKHYGIGWVSM
Site 12T141MANAGPDTNGSQFFI
Site 13S144AGPDTNGSQFFITLT
Site 14T149NGSQFFITLTKPTWL
Site 15T151SQFFITLTKPTWLDG
Site 16T181HSIELQATDGHDRPL
Site 17T189DGHDRPLTNCSIINS
Site 18S192DRPLTNCSIINSGKI
Site 19S196TNCSIINSGKIDVKT
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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