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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VDAC-2
Full Name:
Voltage-dependent anion-selective channel protein 2
Alias:
Outer mitochondrial membrane porin 2; Outer mitochondrial membrane protein porin 2; Putative uncharacterized protein ENSP00000367226; Voltage-dependent anion channel 2
Type:
Membrane, Mitochondrial outer membrane, Mitochondrion, Integral membrane protein
Mass (Da):
31567
Number AA:
294
UniProt ID:
P45880
International Prot ID:
IPI00024145
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0042645
GO:0005741
GO:0046930
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005515
GO:0008308
PhosphoSite+
KinaseNET
Biological Process:
GO:0006820
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
R
P
M
C
I
P
P
S
Y
A
D
L
G
K
A
Site 2
T44
L
V
K
L
D
V
K
T
K
S
C
S
G
V
E
Site 3
S46
K
L
D
V
K
T
K
S
C
S
G
V
E
F
S
Site 4
S48
D
V
K
T
K
S
C
S
G
V
E
F
S
T
S
Site 5
S53
S
C
S
G
V
E
F
S
T
S
G
S
S
N
T
Site 6
S55
S
G
V
E
F
S
T
S
G
S
S
N
T
D
T
Site 7
S57
V
E
F
S
T
S
G
S
S
N
T
D
T
G
K
Site 8
T62
S
G
S
S
N
T
D
T
G
K
V
T
G
T
L
Site 9
T66
N
T
D
T
G
K
V
T
G
T
L
E
T
K
Y
Site 10
T68
D
T
G
K
V
T
G
T
L
E
T
K
Y
K
W
Site 11
Y73
T
G
T
L
E
T
K
Y
K
W
C
E
Y
G
L
Site 12
Y78
T
K
Y
K
W
C
E
Y
G
L
T
F
T
E
K
Site 13
T88
T
F
T
E
K
W
N
T
D
N
T
L
G
T
E
Site 14
T91
E
K
W
N
T
D
N
T
L
G
T
E
I
A
I
Site 15
T112
G
L
K
L
T
F
D
T
T
F
S
P
N
T
G
Site 16
T113
L
K
L
T
F
D
T
T
F
S
P
N
T
G
K
Site 17
S115
L
T
F
D
T
T
F
S
P
N
T
G
K
K
S
Site 18
T118
D
T
T
F
S
P
N
T
G
K
K
S
G
K
I
Site 19
S122
S
P
N
T
G
K
K
S
G
K
I
K
S
S
Y
Site 20
S127
K
K
S
G
K
I
K
S
S
Y
K
R
E
C
I
Site 21
S128
K
S
G
K
I
K
S
S
Y
K
R
E
C
I
N
Site 22
Y129
S
G
K
I
K
S
S
Y
K
R
E
C
I
N
L
Site 23
Y164
Y
E
G
W
L
A
G
Y
Q
M
T
F
D
S
A
Site 24
T167
W
L
A
G
Y
Q
M
T
F
D
S
A
K
S
K
Site 25
S170
G
Y
Q
M
T
F
D
S
A
K
S
K
L
T
R
Site 26
S173
M
T
F
D
S
A
K
S
K
L
T
R
N
N
F
Site 27
Y184
R
N
N
F
A
V
G
Y
R
T
G
D
F
Q
L
Site 28
T193
T
G
D
F
Q
L
H
T
N
V
N
D
G
T
E
Site 29
T199
H
T
N
V
N
D
G
T
E
F
G
G
S
I
Y
Site 30
S204
D
G
T
E
F
G
G
S
I
Y
Q
K
V
C
E
Site 31
Y206
T
E
F
G
G
S
I
Y
Q
K
V
C
E
D
L
Site 32
T215
K
V
C
E
D
L
D
T
S
V
N
L
A
W
T
Site 33
Y236
R
F
G
I
A
A
K
Y
Q
L
D
P
T
A
S
Site 34
T241
A
K
Y
Q
L
D
P
T
A
S
I
S
A
K
V
Site 35
S243
Y
Q
L
D
P
T
A
S
I
S
A
K
V
N
N
Site 36
S245
L
D
P
T
A
S
I
S
A
K
V
N
N
S
S
Site 37
S251
I
S
A
K
V
N
N
S
S
L
I
G
V
G
Y
Site 38
S252
S
A
K
V
N
N
S
S
L
I
G
V
G
Y
T
Site 39
Y258
S
S
L
I
G
V
G
Y
T
Q
T
L
R
P
G
Site 40
T261
I
G
V
G
Y
T
Q
T
L
R
P
G
V
K
L
Site 41
S278
S
A
L
V
D
G
K
S
I
N
A
G
G
H
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation