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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CBX5
Full Name:
Chromobox protein homolog 5
Alias:
Antigen p25; Chromobox 5; Heterochromatin protein 1 alpha; Heterochromatin protein 1 homolog alpha; HP1; HP1 alpha; HP1A; HP1-ALPHA; HP1Hs-alpha
Type:
Transcription, coactivator/corepressor
Mass (Da):
22225
Number AA:
191
UniProt ID:
P45973
International Prot ID:
IPI00024662
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0000118
GO:0035097
Uniprot
OncoNet
Molecular Function:
GO:0019899
GO:0016565
GO:0030674
PhosphoSite+
KinaseNET
Biological Process:
GO:0006333
GO:0006333
GO:0006996
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
G
K
K
T
K
R
T
A
D
S
S
S
S
E
Site 2
S11
K
T
K
R
T
A
D
S
S
S
S
E
D
E
E
Site 3
S12
T
K
R
T
A
D
S
S
S
S
E
D
E
E
E
Site 4
S13
K
R
T
A
D
S
S
S
S
E
D
E
E
E
Y
Site 5
S14
R
T
A
D
S
S
S
S
E
D
E
E
E
Y
V
Site 6
Y20
S
S
E
D
E
E
E
Y
V
V
E
K
V
L
D
Site 7
T50
G
F
S
E
E
H
N
T
W
E
P
E
K
N
L
Site 8
Y70
I
S
E
F
M
K
K
Y
K
K
M
K
E
G
E
Site 9
S85
N
N
K
P
R
E
K
S
E
S
N
K
R
K
S
Site 10
S87
K
P
R
E
K
S
E
S
N
K
R
K
S
N
F
Site 11
S92
S
E
S
N
K
R
K
S
N
F
S
N
S
A
D
Site 12
S95
N
K
R
K
S
N
F
S
N
S
A
D
D
I
K
Site 13
S97
R
K
S
N
F
S
N
S
A
D
D
I
K
S
K
Site 14
S103
N
S
A
D
D
I
K
S
K
K
K
R
E
Q
S
Site 15
S110
S
K
K
K
R
E
Q
S
N
D
I
A
R
G
F
Site 16
T130
P
E
K
I
I
G
A
T
D
S
C
G
D
L
M
Site 17
Y168
P
Q
I
V
I
A
F
Y
E
E
R
L
T
W
H
Site 18
Y177
E
R
L
T
W
H
A
Y
P
E
D
A
E
N
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation