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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RANGAP1
Full Name:
Ran GTPase-activating protein 1
Alias:
Fug1; KIAA1835; RAN GTPase activating protein 1; RanGAP1; RGP1; SD
Type:
GTPase-activating protein for Ran
Mass (Da):
63542
Number AA:
587
UniProt ID:
P46060
International Prot ID:
IPI00294879
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000777
GO:0005643
GO:0005625
Uniprot
OncoNet
Molecular Function:
GO:0005098
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
Q
V
A
G
G
Q
L
S
F
K
G
K
S
L
K
Site 2
S29
Q
L
S
F
K
G
K
S
L
K
L
N
T
A
E
Site 3
S50
K
E
I
E
D
F
D
S
L
E
A
L
R
L
E
Site 4
T60
A
L
R
L
E
G
N
T
V
G
V
E
A
A
R
Site 5
S77
A
K
A
L
E
K
K
S
E
L
K
R
C
H
W
Site 6
S120
Q
L
V
E
L
D
L
S
D
N
A
F
G
P
D
Site 7
T143
L
K
S
S
A
C
F
T
L
Q
E
L
K
L
N
Site 8
T167
K
I
L
A
A
A
L
T
E
C
H
R
K
S
S
Site 9
S173
L
T
E
C
H
R
K
S
S
A
Q
G
K
P
L
Site 10
S174
T
E
C
H
R
K
S
S
A
Q
G
K
P
L
A
Site 11
T247
V
I
N
L
N
D
N
T
F
T
E
K
G
A
V
Site 12
S301
K
L
K
E
L
N
L
S
F
C
E
I
K
R
D
Site 13
S356
N
M
A
K
V
L
A
S
L
S
D
D
E
D
E
Site 14
S358
A
K
V
L
A
S
L
S
D
D
E
D
E
E
E
Site 15
S407
Q
R
G
Q
G
E
K
S
A
T
P
S
R
K
I
Site 16
T409
G
Q
G
E
K
S
A
T
P
S
R
K
I
L
D
Site 17
S411
G
E
K
S
A
T
P
S
R
K
I
L
D
P
N
Site 18
T419
R
K
I
L
D
P
N
T
G
E
P
A
P
V
L
Site 19
S427
G
E
P
A
P
V
L
S
S
P
P
P
A
D
V
Site 20
S428
E
P
A
P
V
L
S
S
P
P
P
A
D
V
S
Site 21
S435
S
P
P
P
A
D
V
S
T
F
L
A
F
P
S
Site 22
T436
P
P
P
A
D
V
S
T
F
L
A
F
P
S
P
Site 23
S442
S
T
F
L
A
F
P
S
P
E
K
L
L
R
L
Site 24
T461
S
V
L
I
A
Q
Q
T
D
T
S
D
P
E
K
Site 25
T463
L
I
A
Q
Q
T
D
T
S
D
P
E
K
V
V
Site 26
S464
I
A
Q
Q
T
D
T
S
D
P
E
K
V
V
S
Site 27
S471
S
D
P
E
K
V
V
S
A
F
L
K
V
S
S
Site 28
S478
S
A
F
L
K
V
S
S
V
F
K
D
E
A
T
Site 29
T485
S
V
F
K
D
E
A
T
V
R
M
A
V
Q
D
Site 30
S504
L
M
Q
K
A
F
N
S
S
S
F
N
S
N
T
Site 31
S506
Q
K
A
F
N
S
S
S
F
N
S
N
T
F
L
Site 32
S509
F
N
S
S
S
F
N
S
N
T
F
L
T
R
L
Site 33
S525
V
H
M
G
L
L
K
S
E
D
K
V
K
A
I
Site 34
Y550
N
H
M
V
Q
Q
D
Y
F
P
K
A
L
A
P
Site 35
S572
K
P
N
S
A
L
E
S
C
S
F
A
R
H
S
Site 36
S574
N
S
A
L
E
S
C
S
F
A
R
H
S
L
L
Site 37
S579
S
C
S
F
A
R
H
S
L
L
Q
T
L
Y
K
Site 38
T583
A
R
H
S
L
L
Q
T
L
Y
K
V
_
_
_
Site 39
Y585
H
S
L
L
Q
T
L
Y
K
V
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation