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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RECQL
Full Name:
ATP-dependent DNA helicase Q1
Alias:
DNA helicase Q1-like; DNA-dependent ATPase Q1; RecQ protein-like; RECQ1; RECQL1
Type:
DNA repair; Helicase; EC 3.6.1.-
Mass (Da):
73457
Number AA:
649
UniProt ID:
P46063
International Prot ID:
IPI00178431
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004003
GO:0000739
PhosphoSite+
KinaseNET
Biological Process:
GO:0006310
GO:0000733
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
A
L
T
E
E
L
D
S
I
T
S
E
L
H
A
Site 2
T29
E
I
Q
I
Q
E
L
T
E
R
Q
Q
E
L
I
Site 3
S53
I
K
Q
C
L
E
D
S
D
A
G
A
S
N
E
Site 4
Y61
D
A
G
A
S
N
E
Y
D
S
S
P
A
A
W
Site 5
S64
A
S
N
E
Y
D
S
S
P
A
A
W
N
K
E
Site 6
S76
N
K
E
D
F
P
W
S
G
K
V
K
D
I
L
Site 7
T99
F
R
P
L
Q
L
E
T
I
N
V
T
M
A
G
Site 8
S120
M
P
T
G
G
G
K
S
L
C
Y
Q
L
P
A
Site 9
T159
K
Q
L
G
I
S
A
T
M
L
N
A
S
S
S
Site 10
S164
S
A
T
M
L
N
A
S
S
S
K
E
H
V
K
Site 11
S166
T
M
L
N
A
S
S
S
K
E
H
V
K
W
V
Site 12
Y188
N
S
E
L
K
L
I
Y
V
T
P
E
K
I
A
Site 13
T190
E
L
K
L
I
Y
V
T
P
E
K
I
A
K
S
Site 14
S197
T
P
E
K
I
A
K
S
K
M
F
M
S
R
L
Site 15
S202
A
K
S
K
M
F
M
S
R
L
E
K
A
Y
E
Site 16
Y208
M
S
R
L
E
K
A
Y
E
A
R
R
F
T
R
Site 17
T214
A
Y
E
A
R
R
F
T
R
I
A
V
D
E
V
Site 18
Y235
G
H
D
F
R
P
D
Y
K
A
L
G
I
L
K
Site 19
S249
K
R
Q
F
P
N
A
S
L
I
G
L
T
A
T
Site 20
Y287
S
F
N
R
P
N
L
Y
Y
E
V
R
Q
K
P
Site 21
Y288
F
N
R
P
N
L
Y
Y
E
V
R
Q
K
P
S
Site 22
Y312
V
K
L
I
N
G
R
Y
K
G
Q
S
G
I
I
Site 23
Y320
K
G
Q
S
G
I
I
Y
C
F
S
Q
K
D
S
Site 24
S323
S
G
I
I
Y
C
F
S
Q
K
D
S
E
Q
V
Site 25
S327
Y
C
F
S
Q
K
D
S
E
Q
V
T
V
S
L
Site 26
T331
Q
K
D
S
E
Q
V
T
V
S
L
Q
N
L
G
Site 27
S333
D
S
E
Q
V
T
V
S
L
Q
N
L
G
I
H
Site 28
Y344
L
G
I
H
A
G
A
Y
H
A
N
L
E
P
E
Site 29
T354
N
L
E
P
E
D
K
T
T
V
H
R
K
W
S
Site 30
T355
L
E
P
E
D
K
T
T
V
H
R
K
W
S
A
Site 31
Y398
M
S
K
S
M
E
N
Y
Y
Q
E
S
G
R
A
Site 32
Y399
S
K
S
M
E
N
Y
Y
Q
E
S
G
R
A
G
Site 33
Y441
N
V
G
Q
Q
K
L
Y
E
M
V
S
Y
C
Q
Site 34
Y446
K
L
Y
E
M
V
S
Y
C
Q
N
I
S
K
C
Site 35
Y492
E
R
K
N
I
T
E
Y
C
R
D
L
I
K
I
Site 36
T511
E
E
L
N
E
K
L
T
P
L
K
L
I
D
S
Site 37
Y554
A
H
F
L
I
Q
Q
Y
L
K
E
D
Y
S
F
Site 38
Y559
Q
Q
Y
L
K
E
D
Y
S
F
T
A
Y
A
T
Site 39
S560
Q
Y
L
K
E
D
Y
S
F
T
A
Y
A
T
I
Site 40
Y564
E
D
Y
S
F
T
A
Y
A
T
I
S
Y
L
K
Site 41
S593
I
T
M
Q
V
T
K
S
T
Q
N
S
F
R
A
Site 42
S597
V
T
K
S
T
Q
N
S
F
R
A
E
S
S
Q
Site 43
S602
Q
N
S
F
R
A
E
S
S
Q
T
C
H
S
E
Site 44
S603
N
S
F
R
A
E
S
S
Q
T
C
H
S
E
Q
Site 45
T605
F
R
A
E
S
S
Q
T
C
H
S
E
Q
G
D
Site 46
S634
A
A
N
M
L
Q
Q
S
G
S
K
N
T
G
A
Site 47
S636
N
M
L
Q
Q
S
G
S
K
N
T
G
A
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation