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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLCO1A2
Full Name:
Solute carrier organic anion transporter family member 1A2
Alias:
OATP; OATP1; OATP1A2; OATP-A; Organic anion transporting polypeptide A; Organic anion-transporting 1; Organic anion-transporting polypeptide 1; SLC21A3; SO1A2; SO1A4; Sodium-independent organic anion transporter; Solute carrier family 21 (organic anion transporter), member 3; Solute carrier family 21 member 3; Solute carrier family 21, member 3; Solute carrier organic anion transporter family, member 1A2
Type:
Transporter
Mass (Da):
74126
Number AA:
670
UniProt ID:
P46721
International Prot ID:
IPI00008254
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0015125
GO:0008514
PhosphoSite+
KinaseNET
Biological Process:
GO:0015711
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
E
T
E
K
R
I
E
T
H
R
I
R
C
L
S
Site 2
S36
A
F
V
S
K
T
L
S
G
S
Y
M
N
S
M
Site 3
S38
V
S
K
T
L
S
G
S
Y
M
N
S
M
L
T
Site 4
S42
L
S
G
S
Y
M
N
S
M
L
T
Q
I
E
R
Site 5
Y113
P
H
F
L
M
N
Q
Y
E
Y
E
S
T
V
S
Site 6
Y115
F
L
M
N
Q
Y
E
Y
E
S
T
V
S
V
S
Site 7
S117
M
N
Q
Y
E
Y
E
S
T
V
S
V
S
G
N
Site 8
T118
N
Q
Y
E
Y
E
S
T
V
S
V
S
G
N
L
Site 9
S120
Y
E
Y
E
S
T
V
S
V
S
G
N
L
S
S
Site 10
S122
Y
E
S
T
V
S
V
S
G
N
L
S
S
N
S
Site 11
S127
S
V
S
G
N
L
S
S
N
S
F
L
C
M
E
Site 12
S129
S
G
N
L
S
S
N
S
F
L
C
M
E
N
G
Site 13
T143
G
T
Q
I
L
R
P
T
Q
D
P
S
E
C
T
Site 14
S147
L
R
P
T
Q
D
P
S
E
C
T
K
E
V
K
Site 15
Y195
K
F
E
N
S
P
L
Y
I
G
L
V
E
T
G
Site 16
T235
N
T
D
D
L
I
I
T
P
T
D
T
R
W
V
Site 17
T237
D
D
L
I
I
T
P
T
D
T
R
W
V
G
A
Site 18
T269
P
F
F
F
L
P
N
T
L
P
K
E
G
L
E
Site 19
T277
L
P
K
E
G
L
E
T
N
A
D
I
I
K
N
Site 20
Y342
M
I
S
F
M
P
K
Y
L
E
Q
Q
Y
G
I
Site 21
Y347
P
K
Y
L
E
Q
Q
Y
G
I
S
S
S
D
A
Site 22
S421
S
V
V
G
I
N
T
S
Y
E
G
I
P
Q
D
Site 23
Y430
E
G
I
P
Q
D
L
Y
V
E
N
D
I
F
A
Site 24
T489
Q
N
C
S
C
I
Q
T
S
G
N
S
S
A
V
Site 25
S545
C
M
K
S
E
E
K
S
L
G
V
G
L
H
T
Site 26
T580
S
T
C
L
H
W
G
T
L
K
C
G
E
S
G
Site 27
S586
G
T
L
K
C
G
E
S
G
A
C
R
I
Y
D
Site 28
Y592
E
S
G
A
C
R
I
Y
D
S
T
T
F
R
Y
Site 29
S634
H
L
P
G
E
N
A
S
S
G
T
E
L
I
E
Site 30
S635
L
P
G
E
N
A
S
S
G
T
E
L
I
E
T
Site 31
T642
S
G
T
E
L
I
E
T
K
V
K
G
K
E
N
Site 32
Y655
E
N
E
C
K
D
I
Y
Q
K
S
T
V
L
K
Site 33
S658
C
K
D
I
Y
Q
K
S
T
V
L
K
D
D
E
Site 34
T659
K
D
I
Y
Q
K
S
T
V
L
K
D
D
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation